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Fenfluramine in the treatment of Dravet syndrome: Results of a third randomized, placebo-controlled clinical trial

Epilepsia (Copenhagen), 2023-10, Vol.64 (10), p.2653-2666

2023

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An Emerging Role for Sigma-1 Receptors in the Treatment of Developmental and Epileptic Encephalopathies

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8416

2021

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Fenfluramine increases survival and reduces markers of neurodegeneration in a mouse model of Dravet syndrome

Epilepsia open, 2024-02, Vol.9 (1), p.300-313

2024

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Safety and Tolerability of the Lidocaine Patch 5%, a Targeted Peripheral Analgesic: A Review of the Literature

Journal of clinical pharmacology, 2003-02, Vol.43 (2), p.111-117

2003

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A pilot, open‐label study of the effectiveness and tolerability of low‐dose ZX008 (fenfluramine HCl) in Lennox‐Gastaut syndrome

Epilepsia (Copenhagen), 2018-10, Vol.59 (10), p.1881-1888

2018

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Fenfluramine treatment for dravet syndrome: Real-world benefits on quality of life from the caregiver perspective

Epilepsy research, 2022-09, Vol.185, p.106976-106976, Article 106976

2022

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Efficacy and Safety of Fenfluramine for the Treatment of Seizures Associated With Lennox-Gastaut Syndrome: A Randomized Clinical Trial

JAMA neurology, 2022-06, Vol.79 (6), p.554

2022

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Fenfluramine significantly reduces day‐to‐day seizure burden by increasing number of seizure‐free days and time between seizures in patients with Dravet syndrome: A time‐to‐event analysis

Epilepsia (Copenhagen), 2022-01, Vol.63 (1), p.130-138

2022

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Fenfluramine treatment for Dravet syndrome: Caregiver- and clinician-reported benefits on the quality of life of patients, caregivers, and families living in Germany, Spain, Italy, and the United Kingdom

Epilepsy research, 2023-02, Vol.190, p.107091-107091, Article 107091

2023

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Impact of fenfluramine on the expected SUDEP mortality rates in patients with Dravet syndrome

Seizure (London, England), 2021-12, Vol.93, p.154-159

2021

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Improved everyday executive functioning following profound reduction in seizure frequency with fenfluramine: Analysis from a phase 3 long-term extension study in children/young adults with Dravet syndrome

Epilepsy & behavior, 2021-08, Vol.121 (Pt A), p.108024, Article 108024

2021

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Life impact of caregiving for severe childhood epilepsy: Results of expert panels and caregiver focus groups

Epilepsy & behavior, 2017-09, Vol.74, p.135-143

2017

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The impact of TK2 deficiency syndrome and its treatment by nucleoside therapy on quality of life

Mitochondrion, 2023-01, Vol.68, p.1-9

2023

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Fenfluramine treatment is associated with improvement in everyday executive function in preschool-aged children (<5 years) with Dravet syndrome: A critical period for early neurodevelopment

Epilepsy & behavior, 2023-01, Vol.138, p.108994, Article 108994

2023

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Fenfluramine provides clinically meaningful reduction in frequency of drop seizures in patients with Lennox–Gastaut syndrome: Interim analysis of an open‐label extension study

Epilepsia (Copenhagen), 2023-01, Vol.64 (1), p.139-151

2023

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Comparison of the effectiveness and tolerability of lidocaine patch 5% versus celecoxib for osteoarthritis-related knee pain: Post hoc analysis of a 12 week, prospective, randomized, active-controlled, open-label, parallel-group trial in adults

Clinical therapeutics, 2008-12, Vol.30 (12), p.2366-2377

2008

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Psychosocial impact on siblings of patients with developmental and epileptic encephalopathies

Epilepsy & behavior, 2020-11, Vol.112, p.107377-107377, Article 107377

2020

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Long-term cardiovascular safety of fenfluramine in patients with Dravet syndrome treated for up to 3 years: Findings from serial echocardiographic assessments

European journal of paediatric neurology, 2022-07, Vol.39, p.35-39

2022

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The humanistic and economic burden of Dravet syndrome on caregivers and families: Implications for future research

Epilepsy & behavior, 2017-05, Vol.70 (Pt A), p.104-109

2017

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Development and validation of the University of Washington caregiver stress and benefit scales for caregivers of children with or without serious health conditions

Quality of life research, 2020-05, Vol.29 (5), p.1361-1371

2020

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Characterizing Pain Flares From the Perspective of Individuals With Symptomatic Knee Osteoarthritis

Arthritis care & research (2010), 2015-08, Vol.67 (8), p.1103-1111

2015

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The words patients use to describe chronic pain: Implications for measuring pain quality

Pain (Amsterdam), 2013-12, Vol.154 (12), p.2722-2728

2013

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Clinical Application of Opioid Equianalgesic Data

The Clinical journal of pain, 2003-09, Vol.19 (5), p.286-297

2003

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Pharmacokinetics and safety of continuously applied lidocaine patches 5

American journal of health-system pharmacy, 2002-11, Vol.59 (22), p.2215-2220

2002

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The Pain Quality Assessment Scale: Assessment of Pain Quality in Carpal Tunnel Syndrome

The journal of pain, 2006-11, Vol.7 (11), p.823-832

2006

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Fenfluramine in the treatment of Dravet syndrome: Results of a third randomized, placebo-controlled clinical trial

An Emerging Role for Sigma-1 Receptors in the Treatment of Developmental and Epileptic Encephalopathies

Fenfluramine increases survival and reduces markers of neurodegeneration in a mouse model of Dravet syndrome

Safety and Tolerability of the Lidocaine Patch 5%, a Targeted Peripheral Analgesic: A Review of the Literature

A pilot, open‐label study of the effectiveness and tolerability of low‐dose ZX008 (fenfluramine HCl) in Lennox‐Gastaut syndrome

Fenfluramine treatment for dravet syndrome: Real-world benefits on quality of life from the caregiver perspective

Efficacy and Safety of Fenfluramine for the Treatment of Seizures Associated With Lennox-Gastaut Syndrome: A Randomized Clinical Trial

Fenfluramine significantly reduces day‐to‐day seizure burden by increasing number of seizure‐free days and time between seizures in patients with Dravet syndrome: A time‐to‐event analysis

Fenfluramine treatment for Dravet syndrome: Caregiver- and clinician-reported benefits on the quality of life of patients, caregivers, and families living in Germany, Spain, Italy, and the United Kingdom

Impact of fenfluramine on the expected SUDEP mortality rates in patients with Dravet syndrome

Improved everyday executive functioning following profound reduction in seizure frequency with fenfluramine: Analysis from a phase 3 long-term extension study in children/young adults with Dravet syndrome

Life impact of caregiving for severe childhood epilepsy: Results of expert panels and caregiver focus groups

The impact of TK2 deficiency syndrome and its treatment by nucleoside therapy on quality of life

Fenfluramine treatment is associated with improvement in everyday executive function in preschool-aged children (<5 years) with Dravet syndrome: A critical period for early neurodevelopment

Fenfluramine provides clinically meaningful reduction in frequency of drop seizures in patients with Lennox–Gastaut syndrome: Interim analysis of an open‐label extension study

Comparison of the effectiveness and tolerability of lidocaine patch 5% versus celecoxib for osteoarthritis-related knee pain: Post hoc analysis of a 12 week, prospective, randomized, active-controlled, open-label, parallel-group trial in adults

Psychosocial impact on siblings of patients with developmental and epileptic encephalopathies

Long-term cardiovascular safety of fenfluramine in patients with Dravet syndrome treated for up to 3 years: Findings from serial echocardiographic assessments

The humanistic and economic burden of Dravet syndrome on caregivers and families: Implications for future research

Development and validation of the University of Washington caregiver stress and benefit scales for caregivers of children with or without serious health conditions

Characterizing Pain Flares From the Perspective of Individuals With Symptomatic Knee Osteoarthritis

The words patients use to describe chronic pain: Implications for measuring pain quality

Clinical Application of Opioid Equianalgesic Data

Pharmacokinetics and safety of continuously applied lidocaine patches 5

The Pain Quality Assessment Scale: Assessment of Pain Quality in Carpal Tunnel Syndrome

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