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Continuing Education Course #2: Current Understanding of Hemostasis

Toxicologic Pathology, 2011-01, Vol.39 (1), p.273-280

Gale, Andrew J.

2011

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Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis

The Journal of clinical investigation, 2013-07, Vol.123 (7), p.3074-3083

2013

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Selective factor VIII activation by the tissue factor–factor VIIa–factor Xa complex

Blood, 2017-10, Vol.130 (14), p.1661-1670

2017

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Sensitive in vivo Visualization of Breast Cancer Using Ratiometric Protease-activatable Fluorescent Imaging Agent, AVB-620

Theranostics, 2017-01, Vol.7 (13), p.3369-3386

2017

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The anticoagulant function of coagulation factor V

Thrombosis and haemostasis, 2012-01, Vol.107 (1), p.15

2012

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An engineered factor Va prevents bleeding induced by anticoagulant wt activated protein C

PloS one, 2014-08, Vol.9 (8), p.e104304

2014

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Detailed Mechanisms of the Inactivation of Factor VIIIa by Activated Protein C in the Presence of Its Cofactors, Protein S and Factor V

The Journal of biological chemistry, 2008-06, Vol.283 (24), p.16355-16362

2008

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Cathepsin G, a leukocyte protease, activates coagulation factor VIII

Thrombosis and haemostasis, 2008-01, Vol.99 (1), p.44

2008

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Molecular Characterization of an Extended Binding Site for Coagulation Factor Va in the Positive Exosite of Activated Protein C

The Journal of biological chemistry, 2002-08, Vol.277 (32), p.28836-28840

2002

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Characterization of a Factor Xa Binding Site on Factor Va near the Arg-506 Activated Protein C Cleavage Site

The Journal of biological chemistry, 2007-07, Vol.282 (30), p.21848-21855

2007

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Augmentation of Human Monocyte Responses to Lipopolysaccharide by the Protein S and Mer/Tyro3 Receptor Tyrosine Kinase Axis

The Journal of immunology (1950), 2018-11, Vol.201 (9), p.2602-2611

2018

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Prothrombin amino terminal region helps protect coagulation factor Va from proteolytic inactivation by activated protein C

Thrombosis and haemostasis, 2009-01, Vol.101 (1), p.55

2009

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Safety, Stability and Pharmacokinetic Properties of (super)Factor Va, a Novel Engineered Coagulation Factor V for Treatment of Severe Bleeding

Pharmaceutical research, 2016-06, Vol.33 (6), p.1517-1526

2016

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Phosphorylation of protein S by platelet kinases enhances its activated protein C cofactor activity

The FASEB journal, 2013-07, Vol.27 (7), p.2918-2925

2013

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Heparin Binding to an Engineered Virus-like Nanoparticle Antagonist

Biomacromolecules, 2017-12, Vol.18 (12), p.4113-4120

2017

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Platelet protein S directly inhibits procoagulant activity on platelets and microparticles

Thrombosis and haemostasis, 2013-02, Vol.109 (2), p.229

2013

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Activated protein C variants with normal cytoprotective but reduced anticoagulant activity

Blood, 2004-09, Vol.104 (6), p.1740-1744

2004

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Three-dimensional model of coagulation factor Va bound to activated protein C

Thrombosis and haemostasis, 2000, Vol.84 (5), p.849

2000

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Interdomain engineered disulfide bond permitting elucidation of mechanisms of inactivation of coagulation factor Va by activated protein C

Protein science, 2002-09, Vol.11 (9), p.2091-2101

2002

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Improved coagulation and haemostasis in haemophilia with inhibitors by combinations of superFactor Va and Factor VIIa

Thrombosis and haemostasis, 2016-03, Vol.115 (3), p.551

2016

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Activation-resistant homozygous protein C R229W mutation causing familial perinatal intracranial hemorrhage and delayed onset of thrombosis

Thrombosis research, 2016-07, Vol.143, p.17-21

2016

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An engineered factor Va prevents bleeding induced by direct-acting oral anticoagulants by different mechanisms

Blood advances, 2020-08, Vol.4 (15), p.3716-3727

2020

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Function of the activated protein C (APC) autolysis loop in activated FVIII inactivation

British journal of haematology, 2011-06, Vol.153 (5), p.644-654

2011

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Heparin Antagonism by Polyvalent Display of Cationic Motifs on Virus-Like Particles

Chembiochem : a European journal of chemical biology, 2009-02, Vol.10 (3), p.503-510

2009

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Engineered virus-like nanoparticles reverse heparin anticoagulation more consistently than protamine in plasma from heparin-treated patients

Thrombosis research, 2011-10, Vol.128 (4), p.e9-e13

2011

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Continuing Education Course #2: Current Understanding of Hemostasis

Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis

Selective factor VIII activation by the tissue factor–factor VIIa–factor Xa complex

Sensitive in vivo Visualization of Breast Cancer Using Ratiometric Protease-activatable Fluorescent Imaging Agent, AVB-620

The anticoagulant function of coagulation factor V

An engineered factor Va prevents bleeding induced by anticoagulant wt activated protein C

Detailed Mechanisms of the Inactivation of Factor VIIIa by Activated Protein C in the Presence of Its Cofactors, Protein S and Factor V

Cathepsin G, a leukocyte protease, activates coagulation factor VIII

Molecular Characterization of an Extended Binding Site for Coagulation Factor Va in the Positive Exosite of Activated Protein C

Characterization of a Factor Xa Binding Site on Factor Va near the Arg-506 Activated Protein C Cleavage Site

Augmentation of Human Monocyte Responses to Lipopolysaccharide by the Protein S and Mer/Tyro3 Receptor Tyrosine Kinase Axis

Prothrombin amino terminal region helps protect coagulation factor Va from proteolytic inactivation by activated protein C

Safety, Stability and Pharmacokinetic Properties of (super)Factor Va, a Novel Engineered Coagulation Factor V for Treatment of Severe Bleeding

Phosphorylation of protein S by platelet kinases enhances its activated protein C cofactor activity

Heparin Binding to an Engineered Virus-like Nanoparticle Antagonist

Platelet protein S directly inhibits procoagulant activity on platelets and microparticles

Activated protein C variants with normal cytoprotective but reduced anticoagulant activity

Three-dimensional model of coagulation factor Va bound to activated protein C

Interdomain engineered disulfide bond permitting elucidation of mechanisms of inactivation of coagulation factor Va by activated protein C

Improved coagulation and haemostasis in haemophilia with inhibitors by combinations of superFactor Va and Factor VIIa

Activation-resistant homozygous protein C R229W mutation causing familial perinatal intracranial hemorrhage and delayed onset of thrombosis

An engineered factor Va prevents bleeding induced by direct-acting oral anticoagulants by different mechanisms

Function of the activated protein C (APC) autolysis loop in activated FVIII inactivation

Heparin Antagonism by Polyvalent Display of Cationic Motifs on Virus-Like Particles

Engineered virus-like nanoparticles reverse heparin anticoagulation more consistently than protamine in plasma from heparin-treated patients

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