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Microtubules, microtubule-interfering agents and apoptosis

Apoptosis (London), 2003-10, Vol.8 (5), p.413-450

2003

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Involvement of mitochondria and recruitment of Fas CD95 signaling in lipid rafts in resveratrol-mediated antimyeloma and antileukemia actions

Oncogene, 2009-09, Vol.28 (36), p.3221-3234

2009

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Fas/CD95 death receptor and lipid rafts: New targets for apoptosis-directed cancer therapy

Drug resistance updates, 2006-02, Vol.9 (1), p.51-73

2006

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Antitumor alkyl-lysophospholipid analog edelfosine induces apoptosis in pancreatic cancer by targeting endoplasmic reticulum

Oncogene, 2012-05, Vol.31 (21), p.2627-2639

2012

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Lipid raft-targeted therapy in multiple myeloma

Oncogene, 2010-07, Vol.29 (26), p.3748-3757

2010

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Proapoptotic role of Hsp90 by its interaction with c-Jun N-terminal kinase in lipid rafts in edelfosine-mediated antileukemic therapy

Oncogene, 2008-03, Vol.27 (12), p.1779-1787

2008

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Involvement of lipid rafts in the localization and dysfunction effect of the antitumor ether phospholipid edelfosine in mitochondria

Cell death & disease, 2011-05, Vol.2 (5), p.e158-e158

2011

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Cytoskeleton-mediated Death Receptor and Ligand Concentration in Lipid Rafts Forms Apoptosis-promoting Clusters in Cancer Chemotherapy

The Journal of biological chemistry, 2005-03, Vol.280 (12), p.11641-11647

2005

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The antitumor ether lipid ET-18-OCH3 induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells

Blood, 2001-12, Vol.98 (13), p.3860-3863

2001

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Apoptotic mechanisms are involved in the death of Strongyloides venezuelensis after triggering of nitric oxide

Parasite immunology, 2012-12, Vol.34 (12), p.570-580

2012

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Biological Activities, Mechanisms of Action and Biomedical Prospect of the Antitumor Ether Phospholipid ET-18-OCH3 (Edelfosine), A Proapoptotic Agent in Tumor Cells

Current drug metabolism, 2002-10, Vol.3 (5), p.491-525

2002

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ET-18-OCH3 (edelfosine): a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 death receptor

Current medicinal chemistry, 2004-12, Vol.11 (24), p.3163-3184

2004

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Intracellular triggering of Fas aggregation and recruitment of apoptotic molecules into Fas-enriched rafts in selective tumor cell apoptosis

The Journal of experimental medicine, 2004-08, Vol.200 (3), p.353-365

2004

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Rapid and Selective Apoptosis in Human Leukemic Cells Induced by Aplidine through a Fas/CD95- and Mitochondrial-mediated Mechanism

Clinical cancer research, 2003-04, Vol.9 (4), p.1535-1545

2003

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Differential gene expression patterns coupled to commitment and acquisition of phenotypic hallmarks during neutrophil differentiation of human leukaemia HL-60 cells

Gene, 2008-08, Vol.419 (1), p.16-26

2008

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Further Naphthylcombretastatins. An Investigation on the Role of the Naphthalene Moiety

Journal of medicinal chemistry, 2005-01, Vol.48 (2), p.556-568

2005

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Cytotoxicity of an Anti-cancer Lysophospholipid through Selective Modification of Lipid Raft Composition

The Journal of biological chemistry, 2005-11, Vol.280 (45), p.38047-38058

2005

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Differential cytostatic and apoptotic effects of ecteinascidin-743 in cancer cells. Transcription-dependent cell cycle arrest and transcription-independent JNK and mitochondrial mediated apoptosis

The Journal of biological chemistry, 2002-11, Vol.277 (44), p.41580-41589

2002

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Involvement of mitochondrial and B-RAF/ERK signaling pathways in berberine-induced apoptosis in human melanoma cells

Anti-cancer drugs, 2011-07, Vol.22 (6), p.507-518

2011

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Novel anti-inflammatory action of edelfosine lacking toxicity with protective effect in experimental colitis

The Journal of pharmacology and experimental therapeutics, 2009-05, Vol.329 (2), p.439-449

2009

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The ether lipid 1-octadecyl-2-methyl-rac-glycero-3-phosphocholine induces expression of fos and jun proto-oncogenes and activates AP-1 transcription factor in human leukaemic cells

Biochemical journal, 1994-09, Vol.302 (2), p.325-329

1994

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Differences in expression of transcription factor AP-1 in human promyelocytic HL-60 cells during differentiation towards macrophages versus granulocytes

Biochemical journal, 1993-08, Vol.294 (1), p.137-144

1993

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Physiological activation of human neutrophils down-regulates CD53 cell surface antigen

Journal of leukocyte biology, 1998-06, Vol.63 (6), p.699-706

1998

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Apoptotic mechanisms are involved in the death of S trongyloides venezuelensis after triggering of nitric oxide

Parasite immunology, 2012-12, Vol.34 (12), p.570-580

2012

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Intracellular triggering of Fas, independently of FasL, as a new mechanism of antitumor ether lipid‐induced apoptosis

International journal of cancer, 2000-03, Vol.85 (5), p.674-682

2000

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Microtubules, microtubule-interfering agents and apoptosis

Involvement of mitochondria and recruitment of Fas CD95 signaling in lipid rafts in resveratrol-mediated antimyeloma and antileukemia actions

Fas/CD95 death receptor and lipid rafts: New targets for apoptosis-directed cancer therapy

Antitumor alkyl-lysophospholipid analog edelfosine induces apoptosis in pancreatic cancer by targeting endoplasmic reticulum

Lipid raft-targeted therapy in multiple myeloma

Proapoptotic role of Hsp90 by its interaction with c-Jun N-terminal kinase in lipid rafts in edelfosine-mediated antileukemic therapy

Involvement of lipid rafts in the localization and dysfunction effect of the antitumor ether phospholipid edelfosine in mitochondria

Cytoskeleton-mediated Death Receptor and Ligand Concentration in Lipid Rafts Forms Apoptosis-promoting Clusters in Cancer Chemotherapy

The antitumor ether lipid ET-18-OCH3 induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells

Apoptotic mechanisms are involved in the death of Strongyloides venezuelensis after triggering of nitric oxide

Biological Activities, Mechanisms of Action and Biomedical Prospect of the Antitumor Ether Phospholipid ET-18-OCH3 (Edelfosine), A Proapoptotic Agent in Tumor Cells

ET-18-OCH3 (edelfosine): a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 death receptor

Intracellular triggering of Fas aggregation and recruitment of apoptotic molecules into Fas-enriched rafts in selective tumor cell apoptosis

Rapid and Selective Apoptosis in Human Leukemic Cells Induced by Aplidine through a Fas/CD95- and Mitochondrial-mediated Mechanism

Differential gene expression patterns coupled to commitment and acquisition of phenotypic hallmarks during neutrophil differentiation of human leukaemia HL-60 cells

Further Naphthylcombretastatins. An Investigation on the Role of the Naphthalene Moiety

Cytotoxicity of an Anti-cancer Lysophospholipid through Selective Modification of Lipid Raft Composition

Differential cytostatic and apoptotic effects of ecteinascidin-743 in cancer cells. Transcription-dependent cell cycle arrest and transcription-independent JNK and mitochondrial mediated apoptosis

Involvement of mitochondrial and B-RAF/ERK signaling pathways in berberine-induced apoptosis in human melanoma cells

Novel anti-inflammatory action of edelfosine lacking toxicity with protective effect in experimental colitis

The ether lipid 1-octadecyl-2-methyl-rac-glycero-3-phosphocholine induces expression of fos and jun proto-oncogenes and activates AP-1 transcription factor in human leukaemic cells

Differences in expression of transcription factor AP-1 in human promyelocytic HL-60 cells during differentiation towards macrophages versus granulocytes

Physiological activation of human neutrophils down-regulates CD53 cell surface antigen

Apoptotic mechanisms are involved in the death of S trongyloides venezuelensis after triggering of nitric oxide

Intracellular triggering of Fas, independently of FasL, as a new mechanism of antitumor ether lipid‐induced apoptosis

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