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Tumor-Associated Fibroblasts Promote HER2-Targeted Therapy Resistance through FGFR2 Activation

Clinical cancer research, 2020-03, Vol.26 (6), p.1432-1448

2020

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FGFR genetic alterations predict for sensitivity to NVP-BGJ398, a selective pan-FGFR inhibitor

Cancer discovery, 2012-12, Vol.2 (12), p.1118-1133

2012

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ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer

Oncotarget, 2015-04, Vol.6 (11), p.9173-9188

2015

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Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (11), p.E1026-E1034

2013

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To Grow or Go: TMEM16A Expression as a Switch between Tumor Growth and Metastasis in SCCHN

Clinical cancer research, 2014-09, Vol.20 (17), p.4673-4688

2014

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CUB-domain-containing protein 1 overexpression in solid cancers promotes cancer cell growth by activating Src family kinases

Oncogene, 2015-10, Vol.34 (44), p.5593-5598

2015

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Class III Phosphatidylinositol 4-Kinase Alpha and Beta Are Novel Host Factor Regulators of Hepatitis C Virus Replication

Journal of Virology, 2009-10, Vol.83 (19), p.10058-10074

2009

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TMEM16A/ANO1 suppression improves response to antibody‐mediated targeted therapy of EGFR and HER2/ERBB2

Genes chromosomes & cancer, 2017-06, Vol.56 (6), p.460-471

2017

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Quantitative Proteomic Verification of Membrane Proteins as Potential Therapeutic Targets Located in the 11q13 Amplicon in Cancers

Journal of proteome research, 2015-09, Vol.14 (9), p.3670-3679

2015

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The pseudophosphatase MK-STYX physically and genetically interacts with the mitochondrial phosphatase PTPMT1

PloS one, 2014-04, Vol.9 (4), p.e93896-e93896

2014

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Protein Kinase D3 Sensitizes RAF Inhibitor RAF265 in Melanoma Cells by Preventing Reactivation of MAPK Signaling

Cancer research (Chicago, Ill.), 2011-06, Vol.71 (12), p.4280-4291

2011

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MK-STYX, a Catalytically Inactive Phosphatase Regulating Mitochondrially Dependent Apoptosis

Molecular and Cellular Biology, 2011-04, Vol.31 (7), p.1357-1368

2011

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Multiple cyclophilins involved in different cellular pathways mediate HCV replication

Virology (New York, N.Y.), 2010-02, Vol.397 (1), p.43-55

2010

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Genome-Wide Characterization of the Zap1p Zinc-Responsive Regulon in Yeast

Proceedings of the National Academy of Sciences - PNAS, 2000-07, Vol.97 (14), p.7957-7962

2000

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High throughput mutagenesis for identification of residues regulating human prostacyclin (hIP) receptor expression and function

PloS one, 2014-06, Vol.9 (6), p.e97973

2014

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Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer

Journal of medicinal chemistry, 2018-04, Vol.61 (7), p.2837-2864

2018

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Down-Regulation of Class II Phosphoinositide 3-Kinase α Expression below a Critical Threshold Induces Apoptotic Cell Death

Molecular cancer research, 2008-04, Vol.6 (4), p.614-623

2008

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Small molecule-facilitated degradation of ANO1 protein: a new targeting approach for anticancer therapeutics

The Journal of biological chemistry, 2014-04, Vol.289 (16), p.11029-11041

2014

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Cholesterol biosynthesis modulation regulates dengue viral replication

Virology (New York, N.Y.), 2009, Vol.389 (1), p.8-19

2009

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Eukaryotic zinc transporters and their regulation

Biometals, 2001-09, Vol.14 (3-4), p.251-270

2001

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The Human ZIP1 Transporter Mediates Zinc Uptake in Human K562 Erythroleukemia Cells

The Journal of biological chemistry, 2001-06, Vol.276 (25), p.22258-22264

2001

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Functional Expression of the Human hZIP2 Zinc Transporter

The Journal of biological chemistry, 2000-02, Vol.275 (8), p.5560-5564

2000

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Variomics Screen Identifies the Re-entrant Loop of the Calcium-activated Chloride Channel ANO1 That Facilitates Channel Activation

The Journal of biological chemistry, 2015-01, Vol.290 (2), p.889-903

2015

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Chemogenomics approaches to novel target discovery

Expert review of proteomics, 2007-06, Vol.4 (3), p.411-419

Gaither, L Alex

2007

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Optimization procedure for small interfering RNA transfection in a 384-well format

Journal of biomolecular screening, 2007-06, Vol.12 (4), p.546-559

2007

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Tumor-Associated Fibroblasts Promote HER2-Targeted Therapy Resistance through FGFR2 Activation

FGFR genetic alterations predict for sensitivity to NVP-BGJ398, a selective pan-FGFR inhibitor

ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer

Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling

To Grow or Go: TMEM16A Expression as a Switch between Tumor Growth and Metastasis in SCCHN

CUB-domain-containing protein 1 overexpression in solid cancers promotes cancer cell growth by activating Src family kinases

Class III Phosphatidylinositol 4-Kinase Alpha and Beta Are Novel Host Factor Regulators of Hepatitis C Virus Replication

TMEM16A/ANO1 suppression improves response to antibody‐mediated targeted therapy of EGFR and HER2/ERBB2

Quantitative Proteomic Verification of Membrane Proteins as Potential Therapeutic Targets Located in the 11q13 Amplicon in Cancers

The pseudophosphatase MK-STYX physically and genetically interacts with the mitochondrial phosphatase PTPMT1

Protein Kinase D3 Sensitizes RAF Inhibitor RAF265 in Melanoma Cells by Preventing Reactivation of MAPK Signaling

MK-STYX, a Catalytically Inactive Phosphatase Regulating Mitochondrially Dependent Apoptosis

Multiple cyclophilins involved in different cellular pathways mediate HCV replication

Genome-Wide Characterization of the Zap1p Zinc-Responsive Regulon in Yeast

High throughput mutagenesis for identification of residues regulating human prostacyclin (hIP) receptor expression and function

Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer

Down-Regulation of Class II Phosphoinositide 3-Kinase α Expression below a Critical Threshold Induces Apoptotic Cell Death

Small molecule-facilitated degradation of ANO1 protein: a new targeting approach for anticancer therapeutics

Cholesterol biosynthesis modulation regulates dengue viral replication

Eukaryotic zinc transporters and their regulation

The Human ZIP1 Transporter Mediates Zinc Uptake in Human K562 Erythroleukemia Cells

Functional Expression of the Human hZIP2 Zinc Transporter

Variomics Screen Identifies the Re-entrant Loop of the Calcium-activated Chloride Channel ANO1 That Facilitates Channel Activation

Chemogenomics approaches to novel target discovery

Optimization procedure for small interfering RNA transfection in a 384-well format

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