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The amino terminus of tau inhibits kinesin-dependent axonal transport: Implications for filament toxicity

Journal of neuroscience research, 2009-02, Vol.87 (2), p.440-451

2009

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Inhibition of GSK-3 induces differentiation and impaired glucose metabolism in renal cancer

Molecular cancer therapeutics, 2014-02, Vol.13 (2), p.285-296

2014

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Characterization of Maleimide-Based Glycogen Synthase Kinase‑3 (GSK-3) Inhibitors as Stimulators of Steroidogenesis

Journal of medicinal chemistry, 2013-06, Vol.56 (12), p.5115-5129

2013

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Identification of HDAC6-Selective Inhibitors of Low Cancer Cell Cytotoxicity

ChemMedChem, 2016-01, Vol.11 (1), p.81-92

2016

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Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease

The Journal of neuroscience, 2016-06, Vol.36 (23), p.6332-6351

2016

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Structure-Activity Relationships and Transcriptomic Analysis of Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors

Antioxidants, 2022-01, Vol.11 (2), p.220

2022

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Identification of a novel inhibitor targeting influenza A virus group 2 hemagglutinins

Antiviral research, 2021-02, Vol.186, p.105013-105013, Article 105013

2021

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Bioactive Flavonoids and Catechols as Hif1 and Nrf2 Protein Stabilizers - Implications for Parkinson's Disease

Aging and disease, 2016-12, Vol.7 (6), p.745-762

2016

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Synthesis, Optimization, and Structure–Activity Relationships of Imidazo[1,2‑a]pyrimidines as Inhibitors of Group 2 Influenza A Viruses

Journal of medicinal chemistry, 2022-10, Vol.65 (20), p.14104-14120

2022

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Optimization of 4‑Aminopiperidines as Inhibitors of Influenza A Viral Entry That Are Synergistic with Oseltamivir

Journal of medicinal chemistry, 2020-03, Vol.63 (6), p.3120-3130

2020

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Soluble guanylyl cyclase is a critical regulator of migraine-associated pain

Cephalalgia, 2018-07, Vol.38 (8), p.1471-1484

2018

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Discovery and Structural Optimization of 4‑(Aminomethyl)benzamides as Potent Entry Inhibitors of Ebola and Marburg Virus Infections

Journal of medicinal chemistry, 2020-07, Vol.63 (13), p.7211-7225

2020

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Synthesis of α‐Ketoamide‐Based Stereoselective Calpain‐1 Inhibitors as Neuroprotective Agents

ChemMedChem, 2020-12, Vol.15 (23), p.2280-2285

2020

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Identification of a potent Nrf2 displacement activator among aspirin-containing prodrugs

Neurochemistry international, 2021-10, Vol.149, p.105148-105148, Article 105148

2021

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GSK-3β Governs Inflammation-Induced NFATc2 Signaling Hubs to Promote Pancreatic Cancer Progression

Molecular cancer therapeutics, 2016-03, Vol.15 (3), p.491-502

2016

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L-ascorbic acid: A true substrate for HIF prolyl hydroxylase?

Biochimie, 2018-04, Vol.147, p.46-54

2018

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A recombinant Cedar virus based high-throughput screening assay for henipavirus antiviral discovery

Antiviral research, 2021-09, Vol.193, p.105084-105084, Article 105084

2021

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From a Natural Product Lead to the Identification of Potent and Selective Benzofuran-3-yl-(indol-3-yl)maleimides as Glycogen Synthase Kinase 3β Inhibitors That Suppress Proliferation and Survival of Pancreatic Cancer Cells

Journal of medicinal chemistry, 2009-04, Vol.52 (7), p.1853-1863

2009

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Activation of Nrf2 and Hypoxic Adaptive Response Contribute to Neuroprotection Elicited by Phenylhydroxamic Acid Selective HDAC6 Inhibitors

ACS chemical neuroscience, 2018-05, Vol.9 (5), p.894-900

2018

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Structure of avian influenza hemagglutinin in complex with a small molecule entry inhibitor

Life science alliance, 2020-08, Vol.3 (8), p.e202000724

2020

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Glycogen synthase kinase 3β inhibitors induce apoptosis in ovarian cancer cells and inhibit in-vivo tumor growth

Anti-cancer drugs, 2011-11, Vol.22 (10), p.978-985

2011

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Structure-Based Design Leads to the Identification of Lithium Mimetics That Block Mania-like Effects in Rodents. Possible New GSK-3β Therapies for Bipolar Disorders

Journal of the American Chemical Society, 2007-07, Vol.129 (26), p.8328-8332

2007

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Identification of a Glycogen Synthase Kinase-3β Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice

ChemMedChem, 2011-09, Vol.6 (9), p.1593-1602

2011

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Identification of a Maleimide-Based Glycogen Synthase Kinase-3 (GSK-3) Inhibitor, BIP-135, That Prolongs the Median Survival Time of Δ7 SMA KO Mouse Model of Spinal Muscular Atrophy

ACS chemical neuroscience, 2012-01, Vol.3 (1), p.5-11

2012

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Structure-Guided Design of a Highly Selective Glycogen Synthase Kinase-3β Inhibitor: a Superior Neuroprotective Pyrazolone Showing Antimania Effects

ChemMedChem, 2011-09, Vol.6 (9), p.1587-1592

2011

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The amino terminus of tau inhibits kinesin-dependent axonal transport: Implications for filament toxicity

Inhibition of GSK-3 induces differentiation and impaired glucose metabolism in renal cancer

Characterization of Maleimide-Based Glycogen Synthase Kinase‑3 (GSK-3) Inhibitors as Stimulators of Steroidogenesis

Identification of HDAC6-Selective Inhibitors of Low Cancer Cell Cytotoxicity

Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease

Structure-Activity Relationships and Transcriptomic Analysis of Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors

Identification of a novel inhibitor targeting influenza A virus group 2 hemagglutinins

Bioactive Flavonoids and Catechols as Hif1 and Nrf2 Protein Stabilizers - Implications for Parkinson's Disease

Synthesis, Optimization, and Structure–Activity Relationships of Imidazo[1,2‑a]pyrimidines as Inhibitors of Group 2 Influenza A Viruses

Optimization of 4‑Aminopiperidines as Inhibitors of Influenza A Viral Entry That Are Synergistic with Oseltamivir

Soluble guanylyl cyclase is a critical regulator of migraine-associated pain

Discovery and Structural Optimization of 4‑(Aminomethyl)benzamides as Potent Entry Inhibitors of Ebola and Marburg Virus Infections

Synthesis of α‐Ketoamide‐Based Stereoselective Calpain‐1 Inhibitors as Neuroprotective Agents

Identification of a potent Nrf2 displacement activator among aspirin-containing prodrugs

GSK-3β Governs Inflammation-Induced NFATc2 Signaling Hubs to Promote Pancreatic Cancer Progression

L-ascorbic acid: A true substrate for HIF prolyl hydroxylase?

A recombinant Cedar virus based high-throughput screening assay for henipavirus antiviral discovery

From a Natural Product Lead to the Identification of Potent and Selective Benzofuran-3-yl-(indol-3-yl)maleimides as Glycogen Synthase Kinase 3β Inhibitors That Suppress Proliferation and Survival of Pancreatic Cancer Cells

Activation of Nrf2 and Hypoxic Adaptive Response Contribute to Neuroprotection Elicited by Phenylhydroxamic Acid Selective HDAC6 Inhibitors

Structure of avian influenza hemagglutinin in complex with a small molecule entry inhibitor

Glycogen synthase kinase 3β inhibitors induce apoptosis in ovarian cancer cells and inhibit in-vivo tumor growth

Structure-Based Design Leads to the Identification of Lithium Mimetics That Block Mania-like Effects in Rodents. Possible New GSK-3β Therapies for Bipolar Disorders

Identification of a Glycogen Synthase Kinase-3β Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice

Identification of a Maleimide-Based Glycogen Synthase Kinase-3 (GSK-3) Inhibitor, BIP-135, That Prolongs the Median Survival Time of Δ7 SMA KO Mouse Model of Spinal Muscular Atrophy

Structure-Guided Design of a Highly Selective Glycogen Synthase Kinase-3β Inhibitor: a Superior Neuroprotective Pyrazolone Showing Antimania Effects

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