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Physiology of SLC12 transporters: lessons from inherited human genetic mutations and genetically engineered mouse knockouts

American Journal of Physiology: Cell Physiology, 2013-04, Vol.304 (8), p.C693-C714

2013

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Molecular physiology of SPAK and OSR1: two Ste20-related protein kinases regulating ion transport

Physiological reviews, 2012-10, Vol.92 (4), p.1577-1617

2012

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Sodium Transporters in Human Health and Disease

Frontiers in physiology, 2021-02, Vol.11, p.588664-588664

2021

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Water Homeostasis and Cell Volume Maintenance and Regulation

Current topics in membranes, 2018, Vol.81, p.3-52

2018

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SPAK and OSR1: STE20 kinases involved in the regulation of ion homoeostasis and volume control in mammalian cells

Biochemical journal, 2008-01, Vol.409 (2), p.321-331

2008

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Volume sensitivity of cation-Cl- cotransporters is modulated by the interaction of two kinases: Ste20-related proline-alanine-rich kinase and WNK4

American Journal of Physiology: Cell Physiology, 2006-01, Vol.290 (1), p.C134-C142

2006

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Calcium-binding protein 39 facilitates molecular interaction between Ste20p proline alanine-rich kinase and oxidative stress response 1 monomers

American Journal of Physiology: Cell Physiology, 2012-12, Vol.303 (11), p.C1198-C1205

2012

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High-grade Glioma Motility Reduced by Genetic Knockdown of KCC3

Cellular physiology and biochemistry, 2012-01, Vol.30 (2), p.466-476

Gagnon, Kenneth B.

2012

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Characterization of SPAK and OSR1, Regulatory Kinases of the Na-K-2Cl Cotransporter

Molecular and Cellular Biology, 2006-01, Vol.26 (2), p.689-698

2006

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Elusive role of the Na-K-2Cl cotransporter in the choroid plexus

American Journal of Physiology: Cell Physiology, 2019-04, Vol.316 (4), p.C522-C524

2019

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WNK4 kinase is a negative regulator of K+-Cl- cotransporters

American journal of physiology. Renal physiology, 2007-04, Vol.292 (4), p.F1197-F1207

2007

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Apoptosis-associated tyrosine kinase scaffolding of protein phosphatase 1 and SPAK reveals a novel pathway for Na-K-2C1 cotransporter regulation

American Journal of Physiology: Cell Physiology, 2007-05, Vol.292 (5), p.C1809-C1815

2007

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Genome-wide analysis of SPAK/OSR1 binding motifs

Physiological genomics, 2007-01, Vol.28 (2), p.223-231

2007

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A Molecular Analysis of the Na+-Independent Cation Chloride Cotransporters

Cellular physiology and biochemistry, 2013-01, Vol.32 (Suppl 1), p.14-31

2013

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Na+‐K+‐2Cl− Cotransporter (NKCC) Physiological Function in Nonpolarized Cells and Transporting Epithelia

Comprehensive Physiology, 2018-03, Vol.8 (2), p.871-901

2018

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Na/H Exchange Regulatory Factor 1 Deficient Mice Show Evidence of Oxidative Stress and Altered Cisplatin Pharmacokinetics

Antioxidants, 2021-06, Vol.10 (7), p.1036

2021

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NHERF1 Loss Upregulates Enzymes of the Pentose Phosphate Pathway in Kidney Cortex

Antioxidants, 2020-09, Vol.9 (9), p.862

2020

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Multiple Pathways for Protein Phosphatase 1 (PP1) Regulation of Na-K-2Cl Cotransporter (NKCC1) Function: THE N-TERMINAL TAIL OF THE Na-K-2Cl COTRANSPORTER SERVES AS A REGULATORY SCAFFOLD FOR Ste20-RELATED PROLINE/ALANINE-RICH KINASE (SPAK) AND PP1

The Journal of biological chemistry, 2010-05, Vol.285 (19), p.14115-14121

2010

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On the substrate recognition and negative regulation of SPAK, a kinase modulating Na+-K+-2Cl- cotransport activity

American Journal of Physiology: Cell Physiology, 2010-09, Vol.299 (3), p.C614-C620

2010

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Kidney Injury Stimulates Apical Translocation of NHERF1

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Pharmacology of Compounds Targeting Cation-Chloride Cotransporter Physiology

Handbook of experimental pharmacology, 2024, Vol.283, p.249

2024

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Kinetics of hyperosmotically stimulated Na-K-2Cl cotransporter in Xenopus laevis oocytes

American Journal of Physiology: Cell Physiology, 2011-11, Vol.301 (5), p.C1074-C1085

2011

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Loss of the Na+/H+ Exchange Regulatory Factor 1 Increases Susceptibility to Cisplatin-Induced Acute Kidney Injury

The American journal of pathology, 2019-06, Vol.189 (6), p.1190-1200

2019

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PBT2 acts through a different mechanism of action than other 8-hydroxyquinolines: an X-ray fluorescence imaging study

Metallomics, 2020-12, Vol.12 (12), p.1979-1994

2020

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Molecular determinants of hyperosmotically activated NKCC1‐mediated K+/K+ exchange

The Journal of physiology, 2010-09, Vol.588 (18), p.3385-3396

2010

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Physiology of SLC12 transporters: lessons from inherited human genetic mutations and genetically engineered mouse knockouts

Molecular physiology of SPAK and OSR1: two Ste20-related protein kinases regulating ion transport

Sodium Transporters in Human Health and Disease

Water Homeostasis and Cell Volume Maintenance and Regulation

SPAK and OSR1: STE20 kinases involved in the regulation of ion homoeostasis and volume control in mammalian cells

Volume sensitivity of cation-Cl- cotransporters is modulated by the interaction of two kinases: Ste20-related proline-alanine-rich kinase and WNK4

Calcium-binding protein 39 facilitates molecular interaction between Ste20p proline alanine-rich kinase and oxidative stress response 1 monomers

High-grade Glioma Motility Reduced by Genetic Knockdown of KCC3

Characterization of SPAK and OSR1, Regulatory Kinases of the Na-K-2Cl Cotransporter

Elusive role of the Na-K-2Cl cotransporter in the choroid plexus

WNK4 kinase is a negative regulator of K+-Cl- cotransporters

Apoptosis-associated tyrosine kinase scaffolding of protein phosphatase 1 and SPAK reveals a novel pathway for Na-K-2C1 cotransporter regulation

Genome-wide analysis of SPAK/OSR1 binding motifs

A Molecular Analysis of the Na+-Independent Cation Chloride Cotransporters

Na+‐K+‐2Cl− Cotransporter (NKCC) Physiological Function in Nonpolarized Cells and Transporting Epithelia

Na/H Exchange Regulatory Factor 1 Deficient Mice Show Evidence of Oxidative Stress and Altered Cisplatin Pharmacokinetics

NHERF1 Loss Upregulates Enzymes of the Pentose Phosphate Pathway in Kidney Cortex

Multiple Pathways for Protein Phosphatase 1 (PP1) Regulation of Na-K-2Cl Cotransporter (NKCC1) Function: THE N-TERMINAL TAIL OF THE Na-K-2Cl COTRANSPORTER SERVES AS A REGULATORY SCAFFOLD FOR Ste20-RELATED PROLINE/ALANINE-RICH KINASE (SPAK) AND PP1

On the substrate recognition and negative regulation of SPAK, a kinase modulating Na+-K+-2Cl- cotransport activity

Kidney Injury Stimulates Apical Translocation of NHERF1

Pharmacology of Compounds Targeting Cation-Chloride Cotransporter Physiology

Kinetics of hyperosmotically stimulated Na-K-2Cl cotransporter in Xenopus laevis oocytes

Loss of the Na+/H+ Exchange Regulatory Factor 1 Increases Susceptibility to Cisplatin-Induced Acute Kidney Injury

PBT2 acts through a different mechanism of action than other 8-hydroxyquinolines: an X-ray fluorescence imaging study

Molecular determinants of hyperosmotically activated NKCC1‐mediated K+/K+ exchange

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