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Mutation of FOXC1 and PITX2 induces cerebral small-vessel disease

The Journal of clinical investigation, 2014-11, Vol.124 (11), p.4877-4881

2014

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Fate Maps of Neural Crest and Mesoderm in the Mammalian Eye

Investigative ophthalmology & visual science, 2005-11, Vol.46 (11), p.4200-4208

2005

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Foxc1 and Foxc2 in the Neural Crest Are Required for Ocular Anterior Segment Development

Investigative ophthalmology & visual science, 2017-03, Vol.58 (3), p.1368-1377

2017

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Expression of the homeobox gene Pitx2 in neural crest is required for optic stalk and ocular anterior segment development

Human molecular genetics, 2005-11, Vol.14 (22), p.3347-3359

2005

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The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development

Developmental biology, 2008-05, Vol.317 (1), p.310-324

2008

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The homeodomain transcription factor PITX2 is required for specifying correct cell fates and establishing angiogenic privilege in the developing cornea

Developmental dynamics, 2014-11, Vol.243 (11), p.1391-1400

2014

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Pitx2 is an upstream activator of extraocular myogenesis and survival

Developmental biology, 2011-01, Vol.349 (2), p.395-405

2011

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Signaling “cross‐talk” is integrated by transcription factors in the development of the anterior segment in the eye

Developmental dynamics, 2009-09, Vol.238 (9), p.2149-2162

2009

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Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field

Development (Cambridge), 2006-04, Vol.133 (8), p.1565-1573

2006

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Pitx2 is required at multiple stages of pituitary organogenesis: pituitary primordium formation and cell specification

Development (Cambridge), 2002-01, Vol.129 (2), p.329-337

2002

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Heterozygous Pitx2 Null Mice Accurately Recapitulate the Ocular Features of Axenfeld-Rieger Syndrome and Congenital Glaucoma

Investigative ophthalmology & visual science, 2016-09, Vol.57 (11), p.5023-5030

2016

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Myocardial Pitx2 Differentially Regulates the Left Atrial Identity and Ventricular Asymmetric Remodeling Programs

Circulation research, 2008-04, Vol.102 (7), p.813-822

2008

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Pitx2 regulates cardiac left–right asymmetry by patterning second cardiac lineage-derived myocardium

Developmental biology, 2006-08, Vol.296 (2), p.437-449

2006

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Human PRKC Apoptosis WT1 Regulator Is a Novel PITX2-interacting Protein That Regulates PITX2 Transcriptional Activity in Ocular Cells

The Journal of biological chemistry, 2009-12, Vol.284 (50), p.34829-34838

2009

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AP-2β Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development

Investigative ophthalmology & visual science, 2016-03, Vol.57 (3), p.1072-1081

2016

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Characterization of mouse orthologue of ELOVL4: genomic organization and spatial and temporal expression

Genomics (San Diego, Calif.), 2004-04, Vol.83 (4), p.626-635

2004

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Mouse Models for the Dissection of CHD7 Functions in Eye Development and the Molecular Basis for Ocular Defects in CHARGE Syndrome

Investigative ophthalmology & visual science, 2015-12, Vol.56 (13), p.7923-7930

2015

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Oculomotor nerve guidance and terminal branching requires interactions with differentiating extraocular muscles

Developmental biology, 2021-08, Vol.476, p.272-281

2021

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The bicoid-related Pitx gene family in development

Mammalian genome, 1999-02, Vol.10 (2), p.197-200

1999

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A targeted approach to genome-wide studies reveals new genetic associations with central corneal thickness

Molecular vision, 2017-12, Vol.23, p.952-962

2017

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Canonical Wnt/β‐catenin signaling is required for maintenance but not activation of Pitx2 expression in neural crest during eye development

Developmental dynamics, 2010-12, Vol.239 (12), p.3215-3225

2010

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β-catenin is required in the neural crest and mesencephalon for pituitary gland organogenesis

BMC developmental biology, 2016-05, Vol.16 (1), p.16-16, Article 16

2016

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Expression of Pitx2 in stromal cells is required for normal hematopoiesis

Blood, 2006-01, Vol.107 (2), p.492-500

2006

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Dosage requirement of Pitx2 for development of multiple organs

Development (Cambridge), 1999-10, Vol.126 (20), p.4643-4651

1999

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AP-2α knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis

Human molecular genetics, 2010-05, Vol.19 (9), p.1791-1804

2010

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Mutation of FOXC1 and PITX2 induces cerebral small-vessel disease

Fate Maps of Neural Crest and Mesoderm in the Mammalian Eye

Foxc1 and Foxc2 in the Neural Crest Are Required for Ocular Anterior Segment Development

Expression of the homeobox gene Pitx2 in neural crest is required for optic stalk and ocular anterior segment development

The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development

The homeodomain transcription factor PITX2 is required for specifying correct cell fates and establishing angiogenic privilege in the developing cornea

Pitx2 is an upstream activator of extraocular myogenesis and survival

Signaling “cross‐talk” is integrated by transcription factors in the development of the anterior segment in the eye

Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field

Pitx2 is required at multiple stages of pituitary organogenesis: pituitary primordium formation and cell specification

Heterozygous Pitx2 Null Mice Accurately Recapitulate the Ocular Features of Axenfeld-Rieger Syndrome and Congenital Glaucoma

Myocardial Pitx2 Differentially Regulates the Left Atrial Identity and Ventricular Asymmetric Remodeling Programs

Pitx2 regulates cardiac left–right asymmetry by patterning second cardiac lineage-derived myocardium

Human PRKC Apoptosis WT1 Regulator Is a Novel PITX2-interacting Protein That Regulates PITX2 Transcriptional Activity in Ocular Cells

AP-2β Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development

Characterization of mouse orthologue of ELOVL4: genomic organization and spatial and temporal expression

Mouse Models for the Dissection of CHD7 Functions in Eye Development and the Molecular Basis for Ocular Defects in CHARGE Syndrome

Oculomotor nerve guidance and terminal branching requires interactions with differentiating extraocular muscles

The bicoid-related Pitx gene family in development

A targeted approach to genome-wide studies reveals new genetic associations with central corneal thickness

Canonical Wnt/β‐catenin signaling is required for maintenance but not activation of Pitx2 expression in neural crest during eye development

β-catenin is required in the neural crest and mesencephalon for pituitary gland organogenesis

Expression of Pitx2 in stromal cells is required for normal hematopoiesis

Dosage requirement of Pitx2 for development of multiple organs

AP-2α knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis

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