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Inducing and exploiting vulnerabilities for the treatment of liver cancer

Nature (London), 2019-10, Vol.574 (7777), p.268-272

2019

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Overall survival and PD‐L1 expression in metastasized malignant melanoma

Cancer, 2011-05, Vol.117 (10), p.2192-2201

2011

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Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanoma

Cancer Immunology, Immunotherapy, 2016-06, Vol.65 (6), p.753-763

2016

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Selective BRAF inhibition decreases tumor-resident lymphocyte frequencies in a mouse model of human melanoma

Oncoimmunology, 2012-08, Vol.1 (5), p.609-617

2012

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Dermal Delivery of Constructs Encoding Cre Recombinase to Induce Skin Tumors in PtenLoxP/LoxP;BrafCA/+ Mice

International journal of molecular sciences, 2016-12, Vol.17 (12), p.2149

2016

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GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors

PloS one, 2012-05, Vol.7 (5), p.e35943-e35943

2012

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Targeting BRAF in an Inducible Murine Model of Melanoma

The American journal of pathology, 2012-09, Vol.181 (3), p.785-794

2012

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Sunitinib pretreatment improves tumor-infiltrating lymphocyte expansion by reduction in intratumoral content of myeloid-derived suppressor cells in human renal cell carcinoma

Cancer Immunology, Immunotherapy, 2015-10, Vol.64 (10), p.1241-1250

2015

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Targeting the MAPK and PI3K pathways in combination with PD1 blockade in melanoma

Oncoimmunology, 2016-12, Vol.5 (12), p.e1238557-e1238557

2016

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Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis

Nature genetics, 2011-12, Vol.43 (12), p.1202-1209

2011

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Dermal Delivery of Constructs Encoding Cre Recombinase to Induce Skin Tumors in Pten super(LoxP/LoxP); B raf super(CA/+) Mice

International journal of molecular sciences, 2016-12, Vol.17 (12), p.2149-2149

2016

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Reduced tumor‐antigen density leads to PD‐1/PD‐L1‐mediated impairment of partially exhausted CD8+ T cells

European journal of immunology, 2012-03, Vol.42 (3), p.662-671

2012

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Mimicking homeostatic proliferation in vitro generates T cells with high anti-tumor function in non-lymphopenic hosts

Cancer Immunology, Immunotherapy, 2013-03, Vol.62 (3), p.503-515

2013

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High expression of GCLC is associated with malignant melanoma of low oxidative phenotype and predicts a better prognosis

Journal of molecular medicine (Berlin, Germany), 2012-08, Vol.90 (8), p.935-944

2012

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Homeostatic proliferation of naïve CD8⁺ T cells depends on CD62L/L-selectin-mediated homing to peripheral LN

European journal of immunology, 2009-11, Vol.39 (11), p.2981-2990

2009

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Targeting BRAF V600E in an Inducible Murine Model of Melanoma

The American journal of pathology, 2012, Vol.181 (3), p.785-794

2012

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Expression of the embryological morphogen Nodal in stage III/IV melanoma

Melanoma research, 2011-12, Vol.21 (6), p.491-501

2011

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Targeting BRAFV600E in an Inducible Murine Model of Melanoma

The American journal of pathology, 2012-09, Vol.181 (3), p.785-794

2012

Volltextzugriff (PDF)

Synchronous BRAF(V600E) and MEK inhibition leads to superior control of murine melanoma by limiting MEK inhibitor induced skin toxicity

OncoTargets and therapy, 2013, Vol.6, p.1649-1658

2013

Volltextzugriff (PDF)

Dermal Delivery of Constructs Encoding Cre Recombinase to Induce Skin Tumors in Pten LoxP/LoxP ;Braf CA/+ Mice

International journal of molecular sciences, 2016-12, Vol.17 (12)

2016

Volltextzugriff (PDF)

Synchronous BRAFV600E and MEK inhibition leads to superior control of murine melanoma by limiting MEK inhibitor induced skin toxicity

OncoTargets and therapy, 2013-11, Vol.6 (default), p.1649-1658

2013

Volltextzugriff (PDF)

Insertional mutagenesis identifies multiple networks of co-operating genes driving intestinal tumorigenesis

Nature genetics, 2011-11, Vol.43 (12), p.1202-1209

2011

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Nodal as a biomarker for melanoma progression and a new therapeutic target for clinical intervention

Expert Review of Dermatology, 2009, Vol.4 (1), p.67-78

2009

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Insertional Mutagenesis in Mice Deficient for p15Ink4b,p16Ink4a, p21Cip1, and p27Kip1 Reveals Cancer Gene Interactions and Correlations with Tumor Phenotypes

Cancer research (Chicago, Ill.), 2010-01, Vol.70 (2), p.520-531

2010

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Altered Replication Timing of IGH Alleles in Burkitt's Lymphoma Depends on IGH Breakpoint Position

Blood, 2004-11, Vol.104 (11), p.4276-4276

2004

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Inducing and exploiting vulnerabilities for the treatment of liver cancer

Overall survival and PD‐L1 expression in metastasized malignant melanoma

Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanoma

Selective BRAF inhibition decreases tumor-resident lymphocyte frequencies in a mouse model of human melanoma

Dermal Delivery of Constructs Encoding Cre Recombinase to Induce Skin Tumors in PtenLoxP/LoxP;BrafCA/+ Mice

GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors

Targeting BRAF in an Inducible Murine Model of Melanoma

Sunitinib pretreatment improves tumor-infiltrating lymphocyte expansion by reduction in intratumoral content of myeloid-derived suppressor cells in human renal cell carcinoma

Targeting the MAPK and PI3K pathways in combination with PD1 blockade in melanoma

Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis

Dermal Delivery of Constructs Encoding Cre Recombinase to Induce Skin Tumors in Pten super(LoxP/LoxP); B raf super(CA/+) Mice

Reduced tumor‐antigen density leads to PD‐1/PD‐L1‐mediated impairment of partially exhausted CD8+ T cells

Mimicking homeostatic proliferation in vitro generates T cells with high anti-tumor function in non-lymphopenic hosts

High expression of GCLC is associated with malignant melanoma of low oxidative phenotype and predicts a better prognosis

Homeostatic proliferation of naïve CD8⁺ T cells depends on CD62L/L-selectin-mediated homing to peripheral LN

Targeting BRAF V600E in an Inducible Murine Model of Melanoma

Expression of the embryological morphogen Nodal in stage III/IV melanoma

Targeting BRAFV600E in an Inducible Murine Model of Melanoma

Synchronous BRAF(V600E) and MEK inhibition leads to superior control of murine melanoma by limiting MEK inhibitor induced skin toxicity

Dermal Delivery of Constructs Encoding Cre Recombinase to Induce Skin Tumors in Pten LoxP/LoxP ;Braf CA/+ Mice

Synchronous BRAFV600E and MEK inhibition leads to superior control of murine melanoma by limiting MEK inhibitor induced skin toxicity

Insertional mutagenesis identifies multiple networks of co-operating genes driving intestinal tumorigenesis

Nodal as a biomarker for melanoma progression and a new therapeutic target for clinical intervention

Insertional Mutagenesis in Mice Deficient for p15Ink4b,p16Ink4a, p21Cip1, and p27Kip1 Reveals Cancer Gene Interactions and Correlations with Tumor Phenotypes

Altered Replication Timing of IGH Alleles in Burkitt's Lymphoma Depends on IGH Breakpoint Position

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