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Metal-based drugs for malaria, trypanosomiasis and leishmaniasis: recent achievements and perspectives

Drug discovery today, 2010-12, Vol.15 (23), p.1070-1078

2010

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Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs

Coordination chemistry reviews, 2009-06, Vol.253 (11), p.1692-1707

2009

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Gold compounds as anticancer agents: chemistry, cellular pharmacology, and preclinical studies

Medicinal research reviews, 2010-05, Vol.30 (3), p.550-580

2010

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Highlights of New Strategies to Increase the Efficacy of Transition Metal Complexes for Cancer Treatments

Molecules (Basel, Switzerland), 2022-12, Vol.28 (1), p.273

2022

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Cytotoxic Ag(I) and Au(I) NHC-carbenes bind DNA and show TrxR inhibition

Journal of inorganic biochemistry, 2020-04, Vol.205, p.110998, Article 110998

2020

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Chemical Modification of Auranofin Yields a New Family of Anticancer Drug Candidates: The Gold(I) Phosphite Analogues

Molecules (Basel, Switzerland), 2023-01, Vol.28 (3), p.1050

2023

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Synthesis, Characterization and Photoactivation Studies on the Novel Pt(IV)-Based [Pt(OCOCH 3 ) 3 (phterpy)] Complex

International journal of molecular sciences, 2023-01, Vol.24 (2), p.1106

2023

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The mode of action of anticancer gold-based drugs: a structural perspective

Chemical communications (Cambridge, England), 2013-10, Vol.49 (86), p.10100-10102

2013

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On the Different Mode of Action of Au(I)/Ag(I)-NHC Bis-Anthracenyl Complexes Towards Selected Target Biomolecules

Molecules (Basel, Switzerland), 2020-11, Vol.25 (22), p.5446

2020

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Emerging Protein Targets for Anticancer Metallodrugs: Inhibition of Thioredoxin Reductase and Cathepsin B by Antitumor Ruthenium(II)−Arene Compounds

Journal of medicinal chemistry, 2008-11, Vol.51 (21), p.6773-6781

2008

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Thermodynamic Evaluation of the Interactions between Anticancer Pt(II) Complexes and Model Proteins

Molecules (Basel, Switzerland), 2021-04, Vol.26 (8), p.2376

2021

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Protein targets for anticancer gold compounds: mechanistic inferences

Anti-cancer agents in medicinal chemistry, 2011-12, Vol.11 (10), p.929

2011

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New uses for old drugs. Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro: Mechanistic and pharmacological implications

FEBS letters, 2008-03, Vol.582 (6), p.844-847

2008

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ESI mass spectrometry and X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme

Chemical communications (Cambridge, England), 2007-01 (2), p.156-158

2007

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Mechanistic Insights Into the Anticancer Properties of the Auranofin Analog Au(PEt3)I: A Theoretical and Experimental Study

Frontiers in chemistry, 2020-09, Vol.8, p.812-812

2020

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Nanoparticles of Mg(OH)2: Synthesis and Application to Paper Conservation

Langmuir, 2005-08, Vol.21 (18), p.8495-8501

2005

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Structural Characterization, Solution Studies, and DFT Calculations on a Series of Binuclear Gold(III) Oxo Complexes: Relationships to Biological Properties

Inorganic chemistry, 2008-04, Vol.47 (7), p.2368-2379

2008

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Interplay between Gold(I)-Ligand Bond Components and Hydrogen Bonding: A Combined Experimental/Computational Study

ACS omega, 2019-01, Vol.4 (1), p.1344-1353

2019

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Proteins as possible targets for antitumor metal complexes: biophysical studies of their interactions

Gabbiani, Chiara

2009

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Proteomic and metallomic strategies for understanding the mode of action of anticancer metallodrugs

Anti-cancer agents in medicinal chemistry, 2010-05, Vol.10 (4), p.324

2010

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Nitrate as a probe of cytochrome c surface: Crystallographic identification of crucial “hot spots” for protein–protein recognition

Journal of inorganic biochemistry, 2014-06, Vol.135, p.58-67

2014

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A focus on the biological targets for coinage metal-NHCs as potential anticancer complexes

Journal of inorganic biochemistry, 2021-04, Vol.217, p.111355-111355, Article 111355

2021

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2D-DIGE analysis of ovarian cancer cell responses to cytotoxic gold compounds

Molecular bioSystems, 2012-01, Vol.8 (4), p.985-993

2012

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Metal compounds as inhibitors of β-amyloid aggregation. Perspectives for an innovative metallotherapeutics on Alzheimer's disease

Coordination chemistry reviews, 2012-10, Vol.256 (19-20), p.2357-2366

2012

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First Crystal Structure for a Gold Carbene–Protein Adduct

Bioconjugate chemistry, 2016-07, Vol.27 (7), p.1584-1587

2016

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Metal-based drugs for malaria, trypanosomiasis and leishmaniasis: recent achievements and perspectives

Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs

Gold compounds as anticancer agents: chemistry, cellular pharmacology, and preclinical studies

Highlights of New Strategies to Increase the Efficacy of Transition Metal Complexes for Cancer Treatments

Cytotoxic Ag(I) and Au(I) NHC-carbenes bind DNA and show TrxR inhibition

Chemical Modification of Auranofin Yields a New Family of Anticancer Drug Candidates: The Gold(I) Phosphite Analogues

Synthesis, Characterization and Photoactivation Studies on the Novel Pt(IV)-Based [Pt(OCOCH 3 ) 3 (phterpy)] Complex

The mode of action of anticancer gold-based drugs: a structural perspective

On the Different Mode of Action of Au(I)/Ag(I)-NHC Bis-Anthracenyl Complexes Towards Selected Target Biomolecules

Emerging Protein Targets for Anticancer Metallodrugs: Inhibition of Thioredoxin Reductase and Cathepsin B by Antitumor Ruthenium(II)−Arene Compounds

Thermodynamic Evaluation of the Interactions between Anticancer Pt(II) Complexes and Model Proteins

Protein targets for anticancer gold compounds: mechanistic inferences

New uses for old drugs. Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro: Mechanistic and pharmacological implications

ESI mass spectrometry and X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme

Mechanistic Insights Into the Anticancer Properties of the Auranofin Analog Au(PEt3)I: A Theoretical and Experimental Study

Nanoparticles of Mg(OH)2: Synthesis and Application to Paper Conservation

Structural Characterization, Solution Studies, and DFT Calculations on a Series of Binuclear Gold(III) Oxo Complexes: Relationships to Biological Properties

Interplay between Gold(I)-Ligand Bond Components and Hydrogen Bonding: A Combined Experimental/Computational Study

Proteins as possible targets for antitumor metal complexes: biophysical studies of their interactions

Proteomic and metallomic strategies for understanding the mode of action of anticancer metallodrugs

Nitrate as a probe of cytochrome c surface: Crystallographic identification of crucial “hot spots” for protein–protein recognition

A focus on the biological targets for coinage metal-NHCs as potential anticancer complexes

2D-DIGE analysis of ovarian cancer cell responses to cytotoxic gold compounds

Metal compounds as inhibitors of β-amyloid aggregation. Perspectives for an innovative metallotherapeutics on Alzheimer's disease

First Crystal Structure for a Gold Carbene–Protein Adduct

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