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A M55V Polymorphism in a Novel SUMO Gene (SUMO-4) Differentially Activates Heat Shock Transcription Factors and Is Associated with Susceptibility to Type I Diabetes Mellitus

The Journal of biological chemistry, 2004-06, Vol.279 (26), p.27233-27238

2004

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Insulin sensitivity is a Rubik’s Cube

The American journal of clinical nutrition, 2016-06, Vol.103 (6), p.1381-1382

Gabbay, Kenneth H

2016

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Ascorbate Synthesis Pathway: DUAL ROLE OF ASCORBATE IN BONE HOMEOSTASIS

The Journal of biological chemistry, 2010-06, Vol.285 (25), p.19510-19520

2010

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A 212-kb Region on Chromosome 6q25 Containing the TAB2 Gene Is Associated With Susceptibility to Type 1 Diabetes

Diabetes (New York, N.Y.), 2004-07, Vol.53 (7), p.1890-1893

2004

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A proline-90 residue unique to SUMO-4 prevents maturation and sumoylation

Biochemical and biophysical research communications, 2005-11, Vol.337 (2), p.517-520

2005

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Aldose reductase modulates cardiac glycogen synthase kinase-3β phosphorylation during ischemia-reperfusion

American journal of physiology. Heart and circulatory physiology, 2012-08, Vol.303 (3), p.H297-H308

2012

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The search for IDDM susceptibility genes: the next generation

Diabetes (New York, N.Y.), 1996-05, Vol.45 (5), p.544-551

1996

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Tyrosine-48 Is the Proton Donor and Histidine-110 Directs Substrate Stereochemical Selectivity in the Reduction Reaction of Human Aldose Reductase: Enzyme Kinetics and Crystal Structure of the Y48H Mutant Enzyme

Biochemistry (Easton), 1994-03, Vol.33 (8), p.2021-2032

1994

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Aldose reductase inhibition in the treatment of diabetic neuropathy: where are we in 2004?

Current diabetes reports, 2004-12, Vol.4 (6), p.405-408

Gabbay, Kenneth H

2004

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Human Aldose Reductase: Rate Constants for a Mechanism Including Interconversion of Ternary Complexes by Recombinant Wild-Type Enzyme

Biochemistry (Easton), 1995-11, Vol.34 (44), p.14356-14365

1995

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An Anion Binding Site in Human Aldose Reductase: Mechanistic Implications for the Binding of Citrate, Cacodylate, and Glucose 6-Phosphate

Biochemistry (Easton), 1994-03, Vol.33 (8), p.2011-2020

1994

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Factors Affecting Counteraction by Methylamines of Urea Effects on Aldose Reductase

Proceedings of the National Academy of Sciences - PNAS, 1999-05, Vol.96 (11), p.6517-6522

1999

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The Alrestatin Double-Decker: Binding of Two Inhibitor Molecules to Human Aldose Reductase Reveals a New Specificity Determinant

Biochemistry (Easton), 1997-12, Vol.36 (51), p.16134-16140

1997

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Ascorbate Synthesis Pathway

The Journal of biological chemistry, 2010-06, Vol.285 (25), p.19510-19520

2010

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Mechanism of Aldose Reductase Inhibition: Binding of NADP+/NADPH and Alrestatin-like Inhibitors

Biochemistry (Easton), 1994-06, Vol.33 (23), p.7157-7165

1994

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Human Aldose Reductase: pK of Tyrosine 48 Reveals the Preferred Ionization State for Catalysis and Inhibition

Biochemistry (Easton), 1995-11, Vol.34 (44), p.14374-14384

1995

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Affinity chromatography of native SUMO proteins using His-tagged recombinant UBC9 bound to Co2+-charged talon resin

Protein expression and purification, 2007-08, Vol.54 (2), p.289-294

2007

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Identification and Characterization of Multiple Osmotic Response Sequences in the Human Aldose Reductase Gene

The Journal of biological chemistry, 1997-06, Vol.272 (26), p.16431-16437

1997

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Human aldehyde reductase promoter allows simultaneous expression of two genes in opposite directions

BioTechniques, 2004-03, Vol.36 (3), p.382-388

2004

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An Unlikely Sugar Substrate Site in the 1.65 Å Structure of the Human Aldose Reductase Holoenzyme Implicated in Diabetic Complications

Science (American Association for the Advancement of Science), 1992-07, Vol.257 (5066), p.81-84

1992

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The HOXD8 locus (2q31) is linked to type I diabetes. Interaction with chromosome 6 and 11 disease susceptibility genes

Diabetes (New York, N.Y.), 1995-01, Vol.44 (1), p.132-136

1995

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Cyclosporine A inhibits the adaptive responses to hypertonicity: A potential mechanism of nephrotoxicity

Journal of the American Society of Nephrology, 2001-12, Vol.12 (12), p.2732-2741

2001

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Mechanism of Human Aldehyde Reductase: Characterization of the Active Site Pocket

Biochemistry (Easton), 1995-09, Vol.34 (35), p.11264-11275

1995

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Association of a CAG/CAA repeat sequence in the TBP gene with type I diabetes

Biochemical and biophysical research communications, 2004-10, Vol.323 (3), p.865-869

2004

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The structure of Apo R268A human aldose reductase: Hinges and latches that control the kinetic mechanism

Biochimica et biophysica acta, 2005-05, Vol.1748 (2), p.201-212

2005

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A M55V Polymorphism in a Novel SUMO Gene (SUMO-4) Differentially Activates Heat Shock Transcription Factors and Is Associated with Susceptibility to Type I Diabetes Mellitus

Insulin sensitivity is a Rubik’s Cube

Ascorbate Synthesis Pathway: DUAL ROLE OF ASCORBATE IN BONE HOMEOSTASIS

A 212-kb Region on Chromosome 6q25 Containing the TAB2 Gene Is Associated With Susceptibility to Type 1 Diabetes

A proline-90 residue unique to SUMO-4 prevents maturation and sumoylation

Aldose reductase modulates cardiac glycogen synthase kinase-3β phosphorylation during ischemia-reperfusion

The search for IDDM susceptibility genes: the next generation

Tyrosine-48 Is the Proton Donor and Histidine-110 Directs Substrate Stereochemical Selectivity in the Reduction Reaction of Human Aldose Reductase: Enzyme Kinetics and Crystal Structure of the Y48H Mutant Enzyme

Aldose reductase inhibition in the treatment of diabetic neuropathy: where are we in 2004?

Human Aldose Reductase: Rate Constants for a Mechanism Including Interconversion of Ternary Complexes by Recombinant Wild-Type Enzyme

An Anion Binding Site in Human Aldose Reductase: Mechanistic Implications for the Binding of Citrate, Cacodylate, and Glucose 6-Phosphate

Factors Affecting Counteraction by Methylamines of Urea Effects on Aldose Reductase

The Alrestatin Double-Decker: Binding of Two Inhibitor Molecules to Human Aldose Reductase Reveals a New Specificity Determinant

Ascorbate Synthesis Pathway

Mechanism of Aldose Reductase Inhibition: Binding of NADP+/NADPH and Alrestatin-like Inhibitors

Human Aldose Reductase: pK of Tyrosine 48 Reveals the Preferred Ionization State for Catalysis and Inhibition

Affinity chromatography of native SUMO proteins using His-tagged recombinant UBC9 bound to Co2+-charged talon resin

Identification and Characterization of Multiple Osmotic Response Sequences in the Human Aldose Reductase Gene

Human aldehyde reductase promoter allows simultaneous expression of two genes in opposite directions

An Unlikely Sugar Substrate Site in the 1.65 Å Structure of the Human Aldose Reductase Holoenzyme Implicated in Diabetic Complications

The HOXD8 locus (2q31) is linked to type I diabetes. Interaction with chromosome 6 and 11 disease susceptibility genes

Cyclosporine A inhibits the adaptive responses to hypertonicity: A potential mechanism of nephrotoxicity

Mechanism of Human Aldehyde Reductase: Characterization of the Active Site Pocket

Association of a CAG/CAA repeat sequence in the TBP gene with type I diabetes

The structure of Apo R268A human aldose reductase: Hinges and latches that control the kinetic mechanism

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