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Superantigen-based immunotherapy: a phase I trial of PNU-214565, a monoclonal antibody-staphylococcal enterotoxin A recombinant fusion protein, in advanced pancreatic and colorectal cancer

Journal of clinical oncology, 1997-05, Vol.15 (5), p.1994-2007

1997

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Cytochrome P450 3A4 is the major enzyme responsible for the metabolism of laquinimod, a novel immunomodulator

Drug metabolism and disposition, 2005-06, Vol.33 (6), p.866

2005

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Determination of estramustine phosphate and its metabolites estromustine, estramustine, estrone and estradiol in human plasma by liquid chromatography with fluorescence detection and gas chromatography with nitrogen-phosphorus and mass spectrometric detection

Journal of chromatography. B, Biomedical sciences and applications, 2000-02, Vol.738 (2), p.267-279

2000

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In vitro metabolism and in vivo pharmacokinetics of quinoline 3-carboxamide derivatives in various species

Xenobiotica, 2005-03, Vol.35 (3), p.293-304

2005

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Time for revival of estrogens in the treatment of advanced prostatic carcinoma? Pharmacokinetics, and endocrine and clinical effects, of a parenteral estrogen regimen

The Prostate, 1999-07, Vol.40 (2), p.76-82

1999

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Differential uptake of estramustine phosphate metabolites and its correlation with the levels of estramustine binding protein in prostate tumor tissue

Clinical cancer research, 1998-09, Vol.4 (9), p.2079-2084

1998

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Identification of cytochrome P4503A as the major subfamily responsible for the metabolism of roquinimex in man

Xenobiotica, 2000, Vol.30 (9), p.905-914

2000

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Metabolism of tauromustine in liver and lung microsomes from various species

Xenobiotica, 1999-08, Vol.29 (8), p.783-792

1999

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Apoptotic tumor cell death induced by estramustine in patients with malignant glioma

Clinical cancer research, 1998-01, Vol.4 (1), p.87-91

1998

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Possible bone-preserving capacity of high-dose intramuscular depot estrogen as compared to orchidectomy in the treatment of patients with prostatic carcinoma

The Prostate, 1997-05, Vol.31 (3), p.193-197

1997

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Metabolic fate of delmopinol in man after mouth rinsing and after oral administration

Xenobiotica, 2000-02, Vol.30 (2), p.179-192

2000

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Pharmacodynamic model of testosterone suppression after intramuscular depot estrogen therapy in prostate cancer

The Prostate, 2000-06, Vol.44 (1), p.26-30

2000

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Metabolism of roquinimex in mouse and rat: an in vitro/in vivo comparison

Xenobiotica, 2000-04, Vol.30 (4), p.371-380

2000

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Uptake and retention of estramustine and the presence of estramustine binding protein in malignant brain tumours in humans

British journal of cancer, 1993-02, Vol.67 (2), p.358-361

1993

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Release of 17-beta-oestradiol from a vaginal ring in postmenopausal women: pharmacokinetic evaluation

Gynecologic and obstetric investigation, 1994, Vol.38 (4), p.253

1994

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Absolute bioavailability of nicotine applied to different nasal regions

European journal of clinical pharmacology, 1991-01, Vol.41 (6), p.585-588

1991

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Uptake of Estramustine Phosphate (Estracyt) Metabolites in Prostatic Cancer

The Journal of urology, 1988-11, Vol.140 (5), p.1058-1062

1988

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Distribution of estramustine in the BT4C rat glioma model

Cancer chemotherapy and pharmacology, 1998, Vol.41 (4), p.317-325

1998

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Dissolution rate-limited absorption and complete bioavailability of roquinimex in man

Biopharmaceutics & drug disposition, 1999-10, Vol.20 (7), p.347-354

1999

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Metabolism of lofepramine and imipramine in liver microsomes from rat and man

Xenobiotica, 1994, Vol.24 (8), p.703-711

1994

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The effect of different dose levels of degradable starch microspheres (Spherex®) on the distribution of a cytotoxic drug after regional administration to tumour-bearing rats

European journal of cancer (1990), 1995-09, Vol.31 (10), p.1701-1705

1995

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Impairment of estramustine phosphate absorption by concurrent intake of milk and food

European journal of clinical pharmacology, 1990-01, Vol.38 (2), p.189-193

1990

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Chromosome aberrations and pharmacokinetics in patients receiving tauromustine as either a single or a repeated dose

Cancer chemotherapy and pharmacology, 1996, Vol.38 (4), p.309-316

1996

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Measurement and characterization of the denitrosation of tauromustine and related nitrosoureas by glutathione transferases in liver cytosol from various species

Carcinogenesis (New York), 1993-06, Vol.14 (6), p.1143-1147

1993

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Pharmacokinetics and testosterone suppression of a single dose of polyestradiol phosphate (Estradurin®) in prostatic cancer patients

The Prostate, 1996-05, Vol.28 (5), p.307-310

1996

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Superantigen-based immunotherapy: a phase I trial of PNU-214565, a monoclonal antibody-staphylococcal enterotoxin A recombinant fusion protein, in advanced pancreatic and colorectal cancer

Cytochrome P450 3A4 is the major enzyme responsible for the metabolism of laquinimod, a novel immunomodulator

Determination of estramustine phosphate and its metabolites estromustine, estramustine, estrone and estradiol in human plasma by liquid chromatography with fluorescence detection and gas chromatography with nitrogen-phosphorus and mass spectrometric detection

In vitro metabolism and in vivo pharmacokinetics of quinoline 3-carboxamide derivatives in various species

Time for revival of estrogens in the treatment of advanced prostatic carcinoma? Pharmacokinetics, and endocrine and clinical effects, of a parenteral estrogen regimen

Differential uptake of estramustine phosphate metabolites and its correlation with the levels of estramustine binding protein in prostate tumor tissue

Identification of cytochrome P4503A as the major subfamily responsible for the metabolism of roquinimex in man

Metabolism of tauromustine in liver and lung microsomes from various species

Apoptotic tumor cell death induced by estramustine in patients with malignant glioma

Possible bone-preserving capacity of high-dose intramuscular depot estrogen as compared to orchidectomy in the treatment of patients with prostatic carcinoma

Metabolic fate of delmopinol in man after mouth rinsing and after oral administration

Pharmacodynamic model of testosterone suppression after intramuscular depot estrogen therapy in prostate cancer

Metabolism of roquinimex in mouse and rat: an in vitro/in vivo comparison

Uptake and retention of estramustine and the presence of estramustine binding protein in malignant brain tumours in humans

Release of 17-beta-oestradiol from a vaginal ring in postmenopausal women: pharmacokinetic evaluation

Absolute bioavailability of nicotine applied to different nasal regions

Uptake of Estramustine Phosphate (Estracyt) Metabolites in Prostatic Cancer

Distribution of estramustine in the BT4C rat glioma model

Dissolution rate-limited absorption and complete bioavailability of roquinimex in man

Metabolism of lofepramine and imipramine in liver microsomes from rat and man

The effect of different dose levels of degradable starch microspheres (Spherex®) on the distribution of a cytotoxic drug after regional administration to tumour-bearing rats

Impairment of estramustine phosphate absorption by concurrent intake of milk and food

Chromosome aberrations and pharmacokinetics in patients receiving tauromustine as either a single or a repeated dose

Measurement and characterization of the denitrosation of tauromustine and related nitrosoureas by glutathione transferases in liver cytosol from various species

Pharmacokinetics and testosterone suppression of a single dose of polyestradiol phosphate (Estradurin®) in prostatic cancer patients

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