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Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

Nature reviews. Endocrinology, 2019-10, Vol.15 (10), p.569-589

2019

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Role of Mitochondria in the Mechanism(s) of Action of Metformin

Frontiers in endocrinology (Lausanne), 2019-05, Vol.10, p.294-294

2019

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Metformin: From Mechanisms of Action to Therapies

Cell metabolism, 2014-12, Vol.20 (6), p.953-966

2014

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Cellular and molecular mechanisms of metformin: an overview

Clinical science (1979), 2012-03, Vol.122 (6), p.253-270

2012

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The Mannose Receptor: From Endocytic Receptor and Biomarker to Regulator of (Meta)Inflammation

Frontiers in immunology, 2021-10, Vol.12, p.765034-765034

2021

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Endoplasmic Reticulum-Mitochondria Crosstalk and Beta-Cell Destruction in Type 1 Diabetes

Frontiers in immunology, 2021-04, Vol.12, p.669492

2021

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Editorial: Immune Regulation of Metabolic Homeostasis

Frontiers in endocrinology (Lausanne), 2022-05, Vol.13, p.929460-929460

2022

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Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

The Journal of physiology, 2006-07, Vol.574 (1), p.41-53

2006

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A single day of high-fat diet feeding induces lipid accumulation and insulin resistance in brown adipose tissue in mice

American journal of physiology: endocrinology and metabolism, 2019-11, Vol.317 (5), p.E820-E830

2019

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Metformin Lowers Plasma Triglycerides by Promoting VLDL-Triglyceride Clearance by Brown Adipose Tissue in Mice

Diabetes (New York, N.Y.), 2014-03, Vol.63 (3), p.880-891

2014

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The degree of liver injury determines the role of p21 in liver regeneration and hepatocarcinogenesis in mice

Hepatology (Baltimore, Md.), 2013-09, Vol.58 (3), p.1143-1152

2013

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Extracellular vesicles derived from stressed beta cells mediate monocyte activation and contribute to islet inflammation

Frontiers in immunology, 2024-07, Vol.15, p.1393248

2024

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S. mansoni -derived omega-1 prevents OVA-specific allergic airway inflammation via hampering of cDC2 migration

PLoS pathogens, 2024-08, Vol.20 (8), p.e1012457

2024

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Effects of a novel polyphenol-rich plant extract on body composition, inflammation, insulin sensitivity, and glucose homeostasis in obese mice

International Journal of Obesity, 2021-09, Vol.45 (9), p.2016-2027

2021

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Dietary yeast-derived mannan oligosaccharides have immune-modulatory properties but do not improve high fat diet-induced obesity and glucose intolerance

PloS one, 2018-05, Vol.13 (5), p.e0196165-e0196165

2018

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Infection with Soil-Transmitted Helminths Is Associated with Increased Insulin Sensitivity

PloS one, 2015-06, Vol.10 (6), p.e0127746-e0127746

2015

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Acetyl-CoA Carboxylase Inhibitor CP640.186 Increases Tubulin Acetylation and Impairs Thrombin-Induced Platelet Aggregation

International journal of molecular sciences, 2021-12, Vol.22 (23), p.13129

2021

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Metformin Prevents High-Glucose–Induced Endothelial Cell Death Through a Mitochondrial Permeability Transition-Dependent Process

Diabetes (New York, N.Y.), 2005-07, Vol.54 (7), p.2179-2187

2005

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Totum-070, a Polyphenol-Rich Plant Extract, Prevents Hypercholesterolemia in High-Fat Diet-Fed Hamsters by Inhibiting Intestinal Cholesterol Absorption

Nutrients, 2023-12, Vol.15 (24), p.5056

2023

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AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

Biochemical journal, 2012-04, Vol.443 (1), p.193-203

2012

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Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation

EMBO molecular medicine, 2023-08, Vol.15 (8), p.e16845-n/a

2023

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Effects of prolonged fasting on AMPK signaling, gene expression, and mitochondrial respiratory chain content in skeletal muscle from lean and obese individuals

American journal of physiology: endocrinology and metabolism, 2013-05, Vol.304 (9), p.E1012-E1021

2013

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Metformin: update on mechanisms of action and repurposing potential

Nature reviews. Endocrinology, 2023-08, Vol.19 (8), p.460-476

2023

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ER stress promotes mitochondrial DNA mediated type-1 interferon response in beta-cells and interleukin-8 driven neutrophil chemotaxis

Frontiers in endocrinology (Lausanne), 2022-09, Vol.13, p.991632-991632

2022

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Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

Role of Mitochondria in the Mechanism(s) of Action of Metformin

Metformin: From Mechanisms of Action to Therapies

Cellular and molecular mechanisms of metformin: an overview

The Mannose Receptor: From Endocytic Receptor and Biomarker to Regulator of (Meta)Inflammation

Endoplasmic Reticulum-Mitochondria Crosstalk and Beta-Cell Destruction in Type 1 Diabetes

Editorial: Immune Regulation of Metabolic Homeostasis

Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis

A single day of high-fat diet feeding induces lipid accumulation and insulin resistance in brown adipose tissue in mice

Metformin Lowers Plasma Triglycerides by Promoting VLDL-Triglyceride Clearance by Brown Adipose Tissue in Mice

The degree of liver injury determines the role of p21 in liver regeneration and hepatocarcinogenesis in mice

Extracellular vesicles derived from stressed beta cells mediate monocyte activation and contribute to islet inflammation

S. mansoni -derived omega-1 prevents OVA-specific allergic airway inflammation via hampering of cDC2 migration

Effects of a novel polyphenol-rich plant extract on body composition, inflammation, insulin sensitivity, and glucose homeostasis in obese mice

Dietary yeast-derived mannan oligosaccharides have immune-modulatory properties but do not improve high fat diet-induced obesity and glucose intolerance

Infection with Soil-Transmitted Helminths Is Associated with Increased Insulin Sensitivity

Acetyl-CoA Carboxylase Inhibitor CP640.186 Increases Tubulin Acetylation and Impairs Thrombin-Induced Platelet Aggregation

Metformin Prevents High-Glucose–Induced Endothelial Cell Death Through a Mitochondrial Permeability Transition-Dependent Process

Totum-070, a Polyphenol-Rich Plant Extract, Prevents Hypercholesterolemia in High-Fat Diet-Fed Hamsters by Inhibiting Intestinal Cholesterol Absorption

AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation

Effects of prolonged fasting on AMPK signaling, gene expression, and mitochondrial respiratory chain content in skeletal muscle from lean and obese individuals

Metformin: update on mechanisms of action and repurposing potential

ER stress promotes mitochondrial DNA mediated type-1 interferon response in beta-cells and interleukin-8 driven neutrophil chemotaxis

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