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Abandoning the Notion of Non-Small Cell Lung Cancer

Trends in molecular medicine, 2019-07, Vol.25 (7), p.585-594

2019

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Cancer-Homing CAR-T Cells and Endogenous Immune Population Dynamics

International journal of molecular sciences, 2021-12, Vol.23 (1), p.405

2021

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Trop‐2 cleavage by ADAM10 is an activator switch for cancer growth and metastasis

Neoplasia (New York, N.Y.), 2021-04, Vol.23 (4), p.415-428

2021

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A non-mutated TROP2 fingerprint in cancer genetics

Frontiers in oncology, 2023-06, Vol.13, p.1151090-1151090

2023

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The Dual Role of Necroptosis in Pancreatic Ductal Adenocarcinoma

International journal of molecular sciences, 2023-08, Vol.24 (16), p.12633

2023

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Novel Ultrastructural Insights into the Clear-Cell Carcinoma of the Pancreas: A Case Report

International journal of molecular sciences, 2024-04, Vol.25 (8), p.4313

2024

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mTrop1/Epcam knockout mice develop congenital tufting enteropathy through dysregulation of intestinal E-cadherin/β-catenin

PloS one, 2012-11, Vol.7 (11), p.e49302-e49302

2012

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TP53 Gene Indels Impact on Cancer Outcomes

Journal of clinical oncology, 2023-01, Vol.41 (1), p.145-147

2023

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The 2EF Antibody Targets a Unique N-Terminal Epitope of Trop-2 and Enhances the In Vivo Activity of the Cancer-Selective 2G10 Antibody

Cancers, 2023-07, Vol.15 (14), p.3721

2023

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Phylogenetic conservation of Trop-2 across species-rodent and primate genomics model anti-Trop-2 therapy for pre-clinical benchmarks

Frontiers in genetics, 2023, Vol.14, p.1297367-1297367

2023

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A Bicistronic CYCLIN D1-TROP2 mRNA Chimera Demonstrates a Novel Oncogenic Mechanism in Human Cancer

Cancer research (Chicago, Ill.), 2008-10, Vol.68 (19), p.8113-8121

2008

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Targeting Trop-2 as a Cancer Driver

Journal of clinical oncology, 2023-10, Vol.41 (29), p.JCO2301207-4692

2023

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The anti-Trop-2 antibody-drug conjugate Sacituzumab Govitecan-effectiveness, pitfalls and promises

Annals of translational medicine, 2022-05, Vol.10 (9), p.501-501

2022

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The Hu2G10 mAb targets the cleaved-activated form of Trop-2 and exploits vulnerability of multiple human cancers

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.e14548-e14548

2022

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Long-range Transcriptome Sequencing Reveals Cancer Cell Growth Regulatory Chimeric mRNA

Neoplasia (New York, N.Y.), 2012-11, Vol.14 (11), p.1087-49

2012

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Distinct lung cancer subtypes associate to distinct drivers of tumor progression

Oncotarget, 2018-10, Vol.9 (85), p.35528-35540

2018

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Cell Growth Stimulation by CRASH, an Asparaginase-like Protein Overexpressed in Human Tumors and Metastatic Breast Cancers

Anticancer research, 2009-04, Vol.29 (4), p.951-963

2009

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Trop-2 inactivates E-cadherin and drives colon cancer metastasis

Journal of clinical oncology, 2021-05, Vol.39 (15_suppl), p.e15576-e15576

2021

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Abstract 340: The Hu2G10 tumor-selective anti-Trop-2 monoclonal antibody targets the cleaved-activated Trop-2 and shows therapeutic efficacy against multiple human cancers

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.340-340

2022

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Inactivation of E-cadherin by Trop-2 drives colon cancer metastasis

Journal of clinical oncology, 2021-01, Vol.39 (3_suppl), p.105-105

2021

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Comment on “Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice”

Science translational medicine, 2016-08, Vol.8 (350)

2016

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Abstract 2608: Hu2G10 antibody-drug conjugates selectively target cleaved-activated Trop-2 in cancer cells and show therapeutic efficacy against multiple human cancers

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.2608-2608

2024

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The trophoblast cell surface antigen 2 and miR-125b axis in urothelial bladder cancer

Oncotarget, 2017-08, Vol.8 (35), p.58642-58653

2017

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Abstract 6310: Phylogenetic conservation of primate Trop-2 underscores favorable pharmacokinetics and lack of toxicity of the cancer-selective Hu2G10 anti-Trop-2

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.6310-6310

2023

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Abandoning the Notion of Non-Small Cell Lung Cancer

Cancer-Homing CAR-T Cells and Endogenous Immune Population Dynamics

Trop‐2 cleavage by ADAM10 is an activator switch for cancer growth and metastasis

A non-mutated TROP2 fingerprint in cancer genetics

The Dual Role of Necroptosis in Pancreatic Ductal Adenocarcinoma

Novel Ultrastructural Insights into the Clear-Cell Carcinoma of the Pancreas: A Case Report

Trop-2 induces ADAM10-mediated cleavage of E-cadherin and drives EMT-less metastasis in colon cancer

mTrop1/Epcam knockout mice develop congenital tufting enteropathy through dysregulation of intestinal E-cadherin/β-catenin

TP53 Gene Indels Impact on Cancer Outcomes

The 2EF Antibody Targets a Unique N-Terminal Epitope of Trop-2 and Enhances the In Vivo Activity of the Cancer-Selective 2G10 Antibody

Phylogenetic conservation of Trop-2 across species-rodent and primate genomics model anti-Trop-2 therapy for pre-clinical benchmarks

A Bicistronic CYCLIN D1-TROP2 mRNA Chimera Demonstrates a Novel Oncogenic Mechanism in Human Cancer

Targeting Trop-2 as a Cancer Driver

The anti-Trop-2 antibody-drug conjugate Sacituzumab Govitecan-effectiveness, pitfalls and promises

The Hu2G10 mAb targets the cleaved-activated form of Trop-2 and exploits vulnerability of multiple human cancers

Long-range Transcriptome Sequencing Reveals Cancer Cell Growth Regulatory Chimeric mRNA

Distinct lung cancer subtypes associate to distinct drivers of tumor progression

Cell Growth Stimulation by CRASH, an Asparaginase-like Protein Overexpressed in Human Tumors and Metastatic Breast Cancers

Trop-2 inactivates E-cadherin and drives colon cancer metastasis

Abstract 340: The Hu2G10 tumor-selective anti-Trop-2 monoclonal antibody targets the cleaved-activated Trop-2 and shows therapeutic efficacy against multiple human cancers

Inactivation of E-cadherin by Trop-2 drives colon cancer metastasis

Comment on “Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice”

Abstract 2608: Hu2G10 antibody-drug conjugates selectively target cleaved-activated Trop-2 in cancer cells and show therapeutic efficacy against multiple human cancers

The trophoblast cell surface antigen 2 and miR-125b axis in urothelial bladder cancer

Abstract 6310: Phylogenetic conservation of primate Trop-2 underscores favorable pharmacokinetics and lack of toxicity of the cancer-selective Hu2G10 anti-Trop-2

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