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Constitutively Active SPAK Causes Hyperkalemia by Activating NCC and Remodeling Distal Tubules

Journal of the American Society of Nephrology, 2017-09, Vol.28 (9), p.2597-2606

2017

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Dietary potassium stimulates Ppp1Ca-Ppp1r1a dephosphorylation of kidney NaCl cotransporter and reduces blood pressure

The Journal of clinical investigation, 2023-11, Vol.133 (21), p.1-16

2023

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Mechanism of Hyperkalemia-Induced Metabolic Acidosis

Journal of the American Society of Nephrology, 2018-05, Vol.29 (5), p.1411-1425

2018

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SPAK-mediated NCC regulation in response to low-K+ diet

American journal of physiology. Renal physiology, 2015-04, Vol.308 (8), p.F923-F931

2015

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Dietary anions control potassium excretion: it is more than a poorly absorbable anion effect

American journal of physiology. Renal physiology, 2023-09, Vol.325 (3), p.F377-F393

2023

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Differential regulation of ROMK (Kir1.1) in distal nephron segments by dietary potassium

American journal of physiology. Renal physiology, 2011-06, Vol.300 (6), p.F1385-F1393

2011

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Integrated compensatory network is activated in the absence of NCC phosphorylation

The Journal of clinical investigation, 2015-05, Vol.125 (5), p.2136-2150

2015

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Hypertension of Kcnmb1⁻/⁻ is linked to deficient K secretion and aldosteronism

Proceedings of the National Academy of Sciences - PNAS, 2009-07, Vol.106 (28), p.11800-11805

2009

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Rapid development of vasopressin resistance in dietary K + deficiency

American journal of physiology. Renal physiology, 2021-05, Vol.320 (5), p.F748-F760

2021

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Potassium-Switch Signaling Pathway Dictates Acute Blood Pressure Response to Dietary Potassium

Hypertension (Dallas, Tex. 1979), 2024-05, Vol.81 (5), p.1044-1054

2024

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SPAK Isoforms and OSR1 Regulate Sodium-Chloride Co-transporters in a Nephron-specific Manner

The Journal of biological chemistry, 2012-11, Vol.287 (45), p.37673-37690

2012

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NEU1 Sialidase Regulates the Sialylation State of CD31 and Disrupts CD31-driven Capillary-like Tube Formation in Human Lung Microvascular Endothelia

The Journal of biological chemistry, 2014-03, Vol.289 (13), p.9121-9135

2014

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BK channels and a new form of hypertension

Kidney international, 2010-11, Vol.78 (10), p.956-962

2010

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A New Understanding of Potassium's Influence Upon Human Health and Renal Physiology

Advances in kidney disease and health (Online), 2023-03, Vol.30 (2), p.137-147

2023

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Identification and localization of BK-beta subunits in the distal nephron of the mouse kidney

American journal of physiology. Renal physiology, 2007-07, Vol.293 (1), p.F350-F359

2007

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BK channels in the kidney

Current opinion in nephrology and hypertension, 2007-09, Vol.16 (5), p.430-436

2007

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Insulin increases the activity of mesangial BK channels through MAPK signaling

American journal of physiology. Renal physiology, 2008-06, Vol.294 (6), p.F1465-F1472

2008

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Intrarenal Metabolite (α‐Ketoglutarate) Signaling Pathway Is Activated by Hnf1α‐Mediated Transcriptional Regulation of OAT10

The FASEB journal, 2019-04, Vol.33 (S1), p.862.34-862.34

2019

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A Renal Potassium‐Switch Prioritizes Dietary Potassium Over Sodium, Driving Salt‐Sensitive Hypertension

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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Synergetic Effects of Hypokalemia and Volume Contraction Combine to Drive Paracrine Secretion of αKG

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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Regulated Dephosphorylation of NCC Shapes the Renal Potassium Switch Pathway

The FASEB journal, 2018-04, Vol.32 (S1), p.620.12-620.12

2018

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Plasma potassium plays a major role in controlling the concentrating ability of the kidney

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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A Novel Genetically Defined Mouse Model of Hypertensive Nephropathy

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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Targeted Knockin of Constitutively Active SPAK (CA‐SPAK) in the Early Distal Convoluted Tubule (DCT1) Causes Hyperkalemic Hypertension

The FASEB journal, 2016-04, Vol.30 (S1)

2016

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BK-{beta}1 subunit: immunolocalization in the mammalian connecting tubule and its role in the kaliuretic response to volume expansion

American journal of physiology. Renal physiology, 2005-04, Vol.288 (4), p.F846-F854

2005

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Constitutively Active SPAK Causes Hyperkalemia by Activating NCC and Remodeling Distal Tubules

Dietary potassium stimulates Ppp1Ca-Ppp1r1a dephosphorylation of kidney NaCl cotransporter and reduces blood pressure

Mechanism of Hyperkalemia-Induced Metabolic Acidosis

SPAK-mediated NCC regulation in response to low-K+ diet

Dietary anions control potassium excretion: it is more than a poorly absorbable anion effect

Differential regulation of ROMK (Kir1.1) in distal nephron segments by dietary potassium

Integrated compensatory network is activated in the absence of NCC phosphorylation

Hypertension of Kcnmb1⁻/⁻ is linked to deficient K secretion and aldosteronism

Rapid development of vasopressin resistance in dietary K + deficiency

Potassium-Switch Signaling Pathway Dictates Acute Blood Pressure Response to Dietary Potassium

SPAK Isoforms and OSR1 Regulate Sodium-Chloride Co-transporters in a Nephron-specific Manner

NEU1 Sialidase Regulates the Sialylation State of CD31 and Disrupts CD31-driven Capillary-like Tube Formation in Human Lung Microvascular Endothelia

BK channels and a new form of hypertension

A New Understanding of Potassium's Influence Upon Human Health and Renal Physiology

Identification and localization of BK-beta subunits in the distal nephron of the mouse kidney

BK channels in the kidney

Insulin increases the activity of mesangial BK channels through MAPK signaling

Intrarenal Metabolite (α‐Ketoglutarate) Signaling Pathway Is Activated by Hnf1α‐Mediated Transcriptional Regulation of OAT10

A Renal Potassium‐Switch Prioritizes Dietary Potassium Over Sodium, Driving Salt‐Sensitive Hypertension

Synergetic Effects of Hypokalemia and Volume Contraction Combine to Drive Paracrine Secretion of αKG

Regulated Dephosphorylation of NCC Shapes the Renal Potassium Switch Pathway

Plasma potassium plays a major role in controlling the concentrating ability of the kidney

A Novel Genetically Defined Mouse Model of Hypertensive Nephropathy

Targeted Knockin of Constitutively Active SPAK (CA‐SPAK) in the Early Distal Convoluted Tubule (DCT1) Causes Hyperkalemic Hypertension

BK-{beta}1 subunit: immunolocalization in the mammalian connecting tubule and its role in the kaliuretic response to volume expansion

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