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Big Data: Challenge and Opportunity for Translational and Industrial Research in Healthcare

Frontiers in digital humanities, 2018-05, Vol.5

2018

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Synthesis and Antitumor Activity of a Heterodinucleotide of BVDU and Gemcitabine

Nucleosides, nucleotides & nucleic acids, 2008-05, Vol.27 (5), p.460-468

2008

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The antinociceptive effect of 2 -chloro-2' -C -methyl -N6-cyclopentyladenosine (2'-Me-CCPA), a highly selective adenosine A1 receptor agonist, in the rat

Pain (Amsterdam), 2007-10, Vol.131 (3), p.281-292

2007

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Nucleoside and non-nucleoside IMP dehydrogenase inhibitors as antitumor and antiviral agents

Current medicinal chemistry, 1999-07, Vol.6 (7), p.599-614

1999

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Inhibition of HIV-1 Replication in Macrophages by Red Blood Cell-Mediated Delivery of a Heterodinucleotide of Lamivudine and Tenofovir

Nucleosides, nucleotides & nucleic acids, 2007-01, Vol.26 (8-9), p.953-957

2007

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Dinucleoside Polyphosphate NAD Analogs as Potential NMN Adenylyltransferase Inhibitors. Synthesis and Biological Evaluation

Nucleosides, nucleotides & nucleic acids, 2003-10, Vol.22 (5-8), p.865-868

2003

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A New Tiazofurin Pronucleotide: Synthesis and Biological Evaluation of CycloSaligenyl-Tiazofurin Monophosphate

Nucleosides, nucleotides & nucleic acids, 2003-05, Vol.22 (5-8), p.869-872

2003

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Antitumor Activity of C-Methyl-β-d-ribofuranosyladenine Nucleoside Ribonucleotide Reductase Inhibitors

Journal of medicinal chemistry, 2005-07, Vol.48 (15), p.4983-4989

2005

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Synthesis, Biological Evaluation, and Molecular Modeling of Ribose-Modified Adenosine Analogues as Adenosine Receptor Agonists

Journal of medicinal chemistry, 2005-03, Vol.48 (5), p.1550-1562

2005

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Ribose-Modified Nucleosides as Ligands for Adenosine Receptors: Synthesis, Conformational Analysis, and Biological Evaluation of 1‘-C-Methyl Adenosine Analogues

Journal of medicinal chemistry, 2002-03, Vol.45 (6), p.1196-1202

2002

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Inhibition of HIV-1 Replication in Macrophages by Red Blood Cell-Mediated Delivery of a Heterodinucleotide of Azidothymidine and 9-(R)-2-(Phosphono Methoxypropyl)adenine

Antiviral chemistry & chemotherapy, 2001-06, Vol.12 (3), p.151-159

2001

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Photoaffinity labeling of A1-adenosine receptors

The Journal of biological chemistry, 1985-11, Vol.260 (27), p.14659-14664

1985

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IMP dehydrogenase as a target of antitumor and antiviral chemotherapy

Farmaco (Società chimica italiana : 1989), 1996-07, Vol.51 (7), p.457

1996

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Synthesis, conformational analysis, and biological activity of new analogues of thiazole-4-carboxamide adenine dinucleotide (TAD) as IMP dehydrogenase inhibitors

Bioorganic & medicinal chemistry, 2005-03, Vol.13 (6), p.2045-2053

2005

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Early Successional Pathways Following Wildfire and Subsequent Silvicultural Treatment in Douglas-Fir/Hardwood Forests, NW California

Forest science, 1993-08, Vol.39 (3), p.561-572

1993

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Erythrocyte-mediated delivery of a new homodinucleotide active against human immunodeficiency virus and herpes simplex virus

Journal of antimicrobial chemotherapy, 2001-06, Vol.47 (6), p.819-827

2001

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Furanfurin and Thiophenfurin: Two Novel Tiazofurin Analogs. Synthesis, Structure, Antitumor Activity, and Interactions with Inosine Monophosphate Dehydrogenase

Journal of medicinal chemistry, 1995-09, Vol.38 (19), p.3829-3837

1995

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2‘-C-Methyl Analogues of Selective Adenosine Receptor Agonists: Synthesis and Binding Studies

Journal of medicinal chemistry, 1998-05, Vol.41 (10), p.1708-1715

1998

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A new C-nucleoside analogue of tiazofurin : synthesis and biological evaluation of 2-β- d-ribofuranosylimidazole-4-carboxamide (imidazofurin)

Bioorganic & medicinal chemistry letters, 2001-01, Vol.11 (1), p.67-69

2001

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Copper complex of a new ribonucleotide reductase inhibitor characterized by antitumoral properties

Pharmacological research, 1992-05, Vol.25, p.312-313

1992

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Tiazofurine ICN Pharmaceuticals

Current opinion in investigational drugs (London, England : 2000), 2000-10, Vol.1 (2), p.257

Grifantini, M

2000

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The antinociceptive effect of 2-chloro-2′- C-methyl-N 6-cyclopentyladenosine (2′-Me-CCPA), a highly selective adenosine A 1 receptor agonist, in the rat

Pain (Amsterdam), 2007, Vol.131 (3), p.281-292

2007

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3,7-Dideazapurine nucleosides. Synthesis and antitumor activity of 1-deazatubercidin and 2-chloro-2'-deoxy-3,7-dideazaadenosine

Journal of medicinal chemistry, 1989-07, Vol.32 (7), p.1463-1466

1989

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Synthesis, Conformational Analysis, and Biological Activity of C-Thioribonucleosides Related to Tiazofurin

Journal of medicinal chemistry, 2000-04, Vol.43 (7), p.1264-1270

2000

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Potent and selective inhibitors of human immunodeficiency virus protease structurally related to L-694,746

Antiviral chemistry & chemotherapy, 1998-07, Vol.9 (4), p.303-309

1998

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Big Data: Challenge and Opportunity for Translational and Industrial Research in Healthcare

Synthesis and Antitumor Activity of a Heterodinucleotide of BVDU and Gemcitabine

The antinociceptive effect of 2 -chloro-2' -C -methyl -N6-cyclopentyladenosine (2'-Me-CCPA), a highly selective adenosine A1 receptor agonist, in the rat

Nucleoside and non-nucleoside IMP dehydrogenase inhibitors as antitumor and antiviral agents

Inhibition of HIV-1 Replication in Macrophages by Red Blood Cell-Mediated Delivery of a Heterodinucleotide of Lamivudine and Tenofovir

Dinucleoside Polyphosphate NAD Analogs as Potential NMN Adenylyltransferase Inhibitors. Synthesis and Biological Evaluation

A New Tiazofurin Pronucleotide: Synthesis and Biological Evaluation of CycloSaligenyl-Tiazofurin Monophosphate

Antitumor Activity of C-Methyl-β-d-ribofuranosyladenine Nucleoside Ribonucleotide Reductase Inhibitors

Synthesis, Biological Evaluation, and Molecular Modeling of Ribose-Modified Adenosine Analogues as Adenosine Receptor Agonists

Ribose-Modified Nucleosides as Ligands for Adenosine Receptors: Synthesis, Conformational Analysis, and Biological Evaluation of 1‘-C-Methyl Adenosine Analogues

Inhibition of HIV-1 Replication in Macrophages by Red Blood Cell-Mediated Delivery of a Heterodinucleotide of Azidothymidine and 9-(R)-2-(Phosphono Methoxypropyl)adenine

Photoaffinity labeling of A1-adenosine receptors

IMP dehydrogenase as a target of antitumor and antiviral chemotherapy

Synthesis, conformational analysis, and biological activity of new analogues of thiazole-4-carboxamide adenine dinucleotide (TAD) as IMP dehydrogenase inhibitors

Early Successional Pathways Following Wildfire and Subsequent Silvicultural Treatment in Douglas-Fir/Hardwood Forests, NW California

Erythrocyte-mediated delivery of a new homodinucleotide active against human immunodeficiency virus and herpes simplex virus

Furanfurin and Thiophenfurin: Two Novel Tiazofurin Analogs. Synthesis, Structure, Antitumor Activity, and Interactions with Inosine Monophosphate Dehydrogenase

2‘-C-Methyl Analogues of Selective Adenosine Receptor Agonists: Synthesis and Binding Studies

A new C-nucleoside analogue of tiazofurin : synthesis and biological evaluation of 2-β- d-ribofuranosylimidazole-4-carboxamide (imidazofurin)

Copper complex of a new ribonucleotide reductase inhibitor characterized by antitumoral properties

Tiazofurine ICN Pharmaceuticals

The antinociceptive effect of 2-chloro-2′- C-methyl-N 6-cyclopentyladenosine (2′-Me-CCPA), a highly selective adenosine A 1 receptor agonist, in the rat

3,7-Dideazapurine nucleosides. Synthesis and antitumor activity of 1-deazatubercidin and 2-chloro-2'-deoxy-3,7-dideazaadenosine

Synthesis, Conformational Analysis, and Biological Activity of C-Thioribonucleosides Related to Tiazofurin

Potent and selective inhibitors of human immunodeficiency virus protease structurally related to L-694,746

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