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BI 6727, A Polo-like Kinase Inhibitor with Improved Pharmacokinetic Profile and Broad Antitumor Activity

Clinical cancer research, 2009-05, Vol.15 (9), p.3094-3102

2009

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BI 2536, a Potent and Selective Inhibitor of Polo-like Kinase 1, Inhibits Tumor Growth In Vivo

Current biology, 2007-02, Vol.17 (4), p.316-322

2007

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Functional interaction of metabotropic glutamate receptor 5 and NMDA-receptor by a metabotropic glutamate receptor 5 positive allosteric modulator

European journal of pharmacology, 2010-08, Vol.639 (1), p.40-46

2010

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BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo

Biochemical journal, 2007-01, Vol.401 (1), p.29-38

2007

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Potent Blockade of Sodium Channels and Protection of Brain Tissue from Ischemia by BIII 890 CL

Proceedings of the National Academy of Sciences - PNAS, 2000-04, Vol.97 (9), p.4944-4949

2000

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Design, Synthesis, and Evaluation of Indolinones as Inhibitors of the Transforming Growth Factor β Receptor I (TGFβRI)

Journal of medicinal chemistry, 2010-10, Vol.53 (20), p.7287-7295

2010

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Functional interaction of metabotropic glutamate receptor 5 and NMDA-receptor by a metabotropic glutamate receptor 5 positive allosteric modulator: Metabotropic Glutamate Receptors and Cognition

European journal of pharmacology, 2010, Vol.639 (1-3), p.40-46

2010

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Synthesis and Structure−Activity Relationships of 6,7-Benzomorphan Derivatives as Use-Dependent Sodium Channel Blockers for the Treatment of Stroke

Journal of medicinal chemistry, 2002-08, Vol.45 (17), p.3755-3764

2002

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N-methyl-D-aspartate receptor channel block by the enantiomeric 6,7-benzomorphans BIII 277 CL and BIII 281 CL

The Journal of pharmacology and experimental therapeutics, 1998-05, Vol.285 (2), p.767

1998

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Synthesis and Structure−Activity Relationships of 6,7-Benzomorphan Derivatives as Antagonists of the NMDA Receptor−Channel Complex

Journal of medicinal chemistry, 1997-08, Vol.40 (18), p.2922-2930

1997

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SYNTHESIS AND IN VITRO AND IN VIVO EVALUATION OF [11C]METHYL-BIII277CL FOR IMAGING THE PCP-BINDING SITE OF THE NMDA RECEPTOR BY PET

Journal of receptors and signal transduction, 2002, Vol.22 (1-4), p.123-139

2002

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Muscarinic Receptor Antagonists in the Treatment of COPD

Analogue‐Based Drug Discovery II, 2010, p.297-318

2010

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Asymmetric Syntheses via Heterocyclic Intermediates, XXVII. Reactions of Metallated Bislactim Ethers of cyclo(-L-Val-Gly-) with (R)- and (S)-Glyceraldehyde and with (S)-Lactaldehyde

Liebigs Annalen der Chemie, 1985-09, Vol.1985 (9), p.1817-1824

1985

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Asymmetric Synthesis via Heterocyclic Intermediates; XXIV 1 . Asymmetric Synthesis of Enantiomerically and Diastereomerically Pure D-Threonine by the Bis-lactim Ether Method

Synthesis (Stuttgart), 1985, Vol.1985 (1), p.55-56

1985

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Asymmetric Synthesis via Heterocyclic Intermediates; XXIV1. Asymmetric Synthesis of Enantiomerically and Diastereomerically Pure D-Threonine by the Bis-lactim Ether Method

Synthesis (Stuttgart), 1985, Vol.1985 (1), p.55-56

1985

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Young Oncologists United (YOU) als interdisziplinäre Nachwuchsarbeitsruppe der DKG gegründet

Forum (Heidelberg), 2024-05, Vol.39 (3), p.173-176

2024

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BI 6727, A Polo-like Kinase Inhibitor with Improved Pharmacokinetic Profile and Broad Antitumor Activity

BI 2536, a Potent and Selective Inhibitor of Polo-like Kinase 1, Inhibits Tumor Growth In Vivo

Functional interaction of metabotropic glutamate receptor 5 and NMDA-receptor by a metabotropic glutamate receptor 5 positive allosteric modulator

BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo

Potent Blockade of Sodium Channels and Protection of Brain Tissue from Ischemia by BIII 890 CL

Design, Synthesis, and Evaluation of Indolinones as Inhibitors of the Transforming Growth Factor β Receptor I (TGFβRI)

Functional interaction of metabotropic glutamate receptor 5 and NMDA-receptor by a metabotropic glutamate receptor 5 positive allosteric modulator: Metabotropic Glutamate Receptors and Cognition

Synthesis and Structure−Activity Relationships of 6,7-Benzomorphan Derivatives as Use-Dependent Sodium Channel Blockers for the Treatment of Stroke

N-methyl-D-aspartate receptor channel block by the enantiomeric 6,7-benzomorphans BIII 277 CL and BIII 281 CL

Synthesis and Structure−Activity Relationships of 6,7-Benzomorphan Derivatives as Antagonists of the NMDA Receptor−Channel Complex

SYNTHESIS AND IN VITRO AND IN VIVO EVALUATION OF [11C]METHYL-BIII277CL FOR IMAGING THE PCP-BINDING SITE OF THE NMDA RECEPTOR BY PET

Muscarinic Receptor Antagonists in the Treatment of COPD

Asymmetric Syntheses via Heterocyclic Intermediates, XXVII. Reactions of Metallated Bislactim Ethers of cyclo(-L-Val-Gly-) with (R)- and (S)-Glyceraldehyde and with (S)-Lactaldehyde

Asymmetric Synthesis via Heterocyclic Intermediates; XXIV 1 . Asymmetric Synthesis of Enantiomerically and Diastereomerically Pure D-Threonine by the Bis-lactim Ether Method

Asymmetric Synthesis via Heterocyclic Intermediates; XXIV1. Asymmetric Synthesis of Enantiomerically and Diastereomerically Pure D-Threonine by the Bis-lactim Ether Method

Young Oncologists United (YOU) als interdisziplinäre Nachwuchsarbeitsruppe der DKG gegründet

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