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Continuing challenges in influenza

Annals of the New York Academy of Sciences, 2014-09, Vol.1323 (1), p.115-139

2014

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T-705 (Favipiravir) Induces Lethal Mutagenesis in Influenza A H1N1 Viruses In Vitro

Journal of Virology, 2013-04, Vol.87 (7), p.3741-3751

2013

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Global update on the susceptibilities of human influenza viruses to neuraminidase inhibitors and the cap-dependent endonuclease inhibitor baloxavir, 2018–2020

Antiviral research, 2022-04, Vol.200, p.105281-105281, Article 105281

2022

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Rapid evolution of A(H5N1) influenza viruses after intercontinental spread to North America

Nature communications, 2023-05, Vol.14 (1), p.3082-3082

2023

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Prevention and treatment of respiratory viral infections: Presentations on antivirals, traditional therapies and host-directed interventions at the 5th ISIRV Antiviral Group conference

Antiviral research, 2018-01, Vol.149, p.118-142

2018

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Influenza polymerase inhibitor resistance: Assessment of the current state of the art - A report of the isirv Antiviral group

Antiviral research, 2021-10, Vol.194, p.105158-105158, Article 105158

2021

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Novel Vaccines and Drugs That Target the Surface Glycoproteins of Influenza Viruses, RSV, Parainfluenza Viruses, and SARS-CoV-2

Viruses, 2022-05, Vol.14 (6), p.1160

2022

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Determination of neuraminidase kinetic constants using whole influenza virus preparations and correction for spectroscopic interference by a fluorogenic substrate

PloS one, 2013-08, Vol.8 (8), p.e71401-e71401

2013

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Influenza A virus polymerase acidic protein E23G/K substitutions weaken key baloxavir drug-binding contacts with minimal impact on replication and transmission

PLoS pathogens, 2022-07, Vol.18 (7), p.e1010698-e1010698

2022

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Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation Influenza Virus Endonuclease Inhibitors

mBio, 2018-05, Vol.9 (2)

2018

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Neuraminidase inhibitor susceptibility and neuraminidase enzyme kinetics of human influenza A and B viruses circulating in Thailand in 2010-2015

PloS one, 2018-01, Vol.13 (1), p.e0190877

2018

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Multiple polymerase acidic (PA) I38X substitutions in influenza A(H1N1)pdm09 virus permit polymerase activity and cause reduced baloxavir inhibition

Journal of antimicrobial chemotherapy, 2021-03, Vol.76 (4), p.957-960

2021

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Antiviral resistance among highly pathogenic influenza A (H5N1) viruses isolated worldwide in 2002–2012 shows need for continued monitoring

Antiviral research, 2013-05, Vol.98 (2), p.297-304

2013

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Screening for Neuraminidase Inhibitor Resistance Markers among Avian Influenza Viruses of the N4, N5, N6, and N8 Neuraminidase Subtypes

Journal of virology, 2018-01, Vol.92 (1)

2018

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Mammalian adaptation of influenza A(H7N9) virus is limited by a narrow genetic bottleneck

Nature communications, 2015-04, Vol.6 (1), p.6553-6553, Article 6553

2015

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Unique Determinants of Neuraminidase Inhibitor Resistance among N3, N7, and N9 Avian Influenza Viruses

Journal of virology, 2015-11, Vol.89 (21), p.10891-10900

2015

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Virulence May Determine the Necessary Duration and Dosage of Oseltamivir Treatment for Highly Pathogenic A/Vietnam/1203/04 Influenza Virus in Mice

The Journal of infectious diseases, 2005-08, Vol.192 (4), p.665-672

2005

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Cross-species spill-over potential of the H9N2 bat influenza A virus

Nature communications, 2024-04, Vol.15 (1), p.3449-3449

2024

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Effect of neuraminidase inhibitor-resistant mutations on pathogenicity of clade 2.2 A/Turkey/15/06 (H5N1) influenza virus in ferrets

PLoS pathogens, 2010-05, Vol.6 (5), p.e1000933-e1000933

2010

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Risk Assessment of H2N2 Influenza Viruses from the Avian Reservoir

Journal of Virology, 2014-01, Vol.88 (2), p.1175-1188

2014

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The pH of Activation of the Hemagglutinin Protein Regulates H5N1 Influenza Virus Pathogenicity and Transmissibility in Ducks

Journal of Virology, 2010-02, Vol.84 (3), p.1527-1535

2010

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The polymerase complex genes contribute to the high virulence of the human H5N1 influenza virus isolate A/Vietnam/1203/04

The Journal of experimental medicine, 2006-03, Vol.203 (3), p.689-697

2006

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Fitness Costs for Influenza B Viruses Carrying Neuraminidase Inhibitor-Resistant Substitutions: Underscoring the Importance of E119A and H274Y

Antimicrobial agents and chemotherapy, 2014-05, Vol.58 (5), p.2718-2730

2014

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Epitope Mapping of the Hemagglutinin Molecule of a Highly Pathogenic H5N1 Influenza Virus by Using Monoclonal Antibodies

Journal of Virology, 2007-12, Vol.81 (23), p.12911-12917

2007

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Neuraminidase Inhibitor-Resistant Recombinant A/Vietnam/1203/04 (H5N1) Influenza Viruses Retain Their Replication Efficiency and Pathogenicity In Vitro and In Vivo

Journal of Virology, 2007-11, Vol.81 (22), p.12418-12426

2007

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Continuing challenges in influenza

T-705 (Favipiravir) Induces Lethal Mutagenesis in Influenza A H1N1 Viruses In Vitro

Global update on the susceptibilities of human influenza viruses to neuraminidase inhibitors and the cap-dependent endonuclease inhibitor baloxavir, 2018–2020

Rapid evolution of A(H5N1) influenza viruses after intercontinental spread to North America

Prevention and treatment of respiratory viral infections: Presentations on antivirals, traditional therapies and host-directed interventions at the 5th ISIRV Antiviral Group conference

Influenza polymerase inhibitor resistance: Assessment of the current state of the art - A report of the isirv Antiviral group

Novel Vaccines and Drugs That Target the Surface Glycoproteins of Influenza Viruses, RSV, Parainfluenza Viruses, and SARS-CoV-2

Determination of neuraminidase kinetic constants using whole influenza virus preparations and correction for spectroscopic interference by a fluorogenic substrate

Influenza A virus polymerase acidic protein E23G/K substitutions weaken key baloxavir drug-binding contacts with minimal impact on replication and transmission

Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation Influenza Virus Endonuclease Inhibitors

Neuraminidase inhibitor susceptibility and neuraminidase enzyme kinetics of human influenza A and B viruses circulating in Thailand in 2010-2015

Multiple polymerase acidic (PA) I38X substitutions in influenza A(H1N1)pdm09 virus permit polymerase activity and cause reduced baloxavir inhibition

Antiviral resistance among highly pathogenic influenza A (H5N1) viruses isolated worldwide in 2002–2012 shows need for continued monitoring

Screening for Neuraminidase Inhibitor Resistance Markers among Avian Influenza Viruses of the N4, N5, N6, and N8 Neuraminidase Subtypes

Mammalian adaptation of influenza A(H7N9) virus is limited by a narrow genetic bottleneck

Unique Determinants of Neuraminidase Inhibitor Resistance among N3, N7, and N9 Avian Influenza Viruses

Virulence May Determine the Necessary Duration and Dosage of Oseltamivir Treatment for Highly Pathogenic A/Vietnam/1203/04 Influenza Virus in Mice

Cross-species spill-over potential of the H9N2 bat influenza A virus

Effect of neuraminidase inhibitor-resistant mutations on pathogenicity of clade 2.2 A/Turkey/15/06 (H5N1) influenza virus in ferrets

Risk Assessment of H2N2 Influenza Viruses from the Avian Reservoir

The pH of Activation of the Hemagglutinin Protein Regulates H5N1 Influenza Virus Pathogenicity and Transmissibility in Ducks

The polymerase complex genes contribute to the high virulence of the human H5N1 influenza virus isolate A/Vietnam/1203/04

Fitness Costs for Influenza B Viruses Carrying Neuraminidase Inhibitor-Resistant Substitutions: Underscoring the Importance of E119A and H274Y

Epitope Mapping of the Hemagglutinin Molecule of a Highly Pathogenic H5N1 Influenza Virus by Using Monoclonal Antibodies

Neuraminidase Inhibitor-Resistant Recombinant A/Vietnam/1203/04 (H5N1) Influenza Viruses Retain Their Replication Efficiency and Pathogenicity In Vitro and In Vivo

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