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Preclinical Profile of VX-950, a Potent, Selective, and Orally Bioavailable Inhibitor of Hepatitis C Virus NS3-4A Serine Protease

Antimicrobial Agents and Chemotherapy, 2006-03, Vol.50 (3), p.899-909

2006

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Effect of injection parameters on the performance and emission characteristics of a variable compression ratio diesel engine with plastic oil blends – An experimental study

Energy & environment (Essex, England), 2018-06, Vol.29 (4), p.492-510

2018

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In Vitro Phenotypic Characterization of Hepatitis C Virus NS3 Protease Variants Observed in Clinical Studies of Telaprevir

Antimicrobial Agents and Chemotherapy, 2013-12, Vol.57 (12), p.6236-6245

2013

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Viral and cellular RNA helicases as antiviral targets

Nature reviews. Drug discovery, 2005-10, Vol.4 (10), p.845-853

2005

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In Vitro Studies of Cross-resistance Mutations against Two Hepatitis C Virus Serine Protease Inhibitors, VX-950 and BILN 2061

The Journal of biological chemistry, 2005-11, Vol.280 (44), p.36784-36791

2005

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Improvement of biodiesel methanol blends performance in a variable compression ratio engine using response surface methodology

Alexandria engineering journal, 2016-06, Vol.55 (2), p.1201-1209

2016

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Benzimidazole-containing HCV NS5A inhibitors: Effect of 4-substituted pyrrolidines in balancing genotype 1a and 1b potency

Bioorganic & medicinal chemistry letters, 2015-02, Vol.25 (4), p.944-947

2015

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Characterization of V36C, a Novel Amino Acid Substitution Conferring Hepatitis C Virus (HCV) Resistance to Telaprevir, a Potent Peptidomimetic Inhibitor of HCV Protease

Antimicrobial Agents and Chemotherapy, 2010-06, Vol.54 (6), p.2681-2683

2010

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Heat transfer from a horizontal fin array by natural convection and radiation—A conjugate analysis

International journal of heat and mass transfer, 2006-09, Vol.49 (19), p.3379-3391

2006

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Recent developments in the design of specific Matrix Metalloproteinase inhibitors aided by structural and computational studies

Current pharmaceutical design, 2005-02, Vol.11 (3), p.295-322

Rao, B Govinda

2005

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Novel thiol-based TACE inhibitors: Rational design, synthesis, and SAR of thiol-containing aryl sulfonamides

Bioorganic & medicinal chemistry letters, 2007-04, Vol.17 (8), p.2250-2253

2007

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Novel thiol-based TACE inhibitors. Part 2: Rational design, synthesis, and SAR of thiol-containing aryl sulfones

Bioorganic & medicinal chemistry, 2008, Vol.18 (1), p.44-48

2008

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In vitro resistance studies of hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061: structural analysis indicates different resistance mechanisms

The Journal of biological chemistry, 2004-04, Vol.279 (17), p.17508-17514

2004

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Genotypic and phenotypic analyses of hepatitis C virus variants observed in clinical studies of VX-222, a nonnucleoside NS5B polymerase inhibitor

Antimicrobial agents and chemotherapy, 2014-09, Vol.58 (9), p.5456-5465

2014

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Discovery of Novel Thiophene-Based, Thumb Pocket 2 Allosteric Inhibitors of the Hepatitis C NS5B Polymerase with Improved Potency and Physicochemical Profiles

Journal of medicinal chemistry, 2016-07, Vol.59 (13), p.6293-6302

2016

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Nonstructural protein 5A (NS5A) and human replication protein A increase the processivity of hepatitis C virus NS5B polymerase activity in vitro

Journal of virology, 2015-01, Vol.89 (1), p.165-180

2015

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Discovery of Novel Allosteric HCV NS5B Inhibitors. 2. Lactam-Containing Thiophene Carboxylates

ACS medicinal chemistry letters, 2017-02, Vol.8 (2), p.251-255

2017

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Phenotypic Characterization of Resistant Val36 Variants of Hepatitis C Virus NS3-4A Serine Protease

Antimicrobial Agents and Chemotherapy, 2008-01, Vol.52 (1), p.110-120

2008

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FURSMASA: A new approach to rapid scoring functions that uses a MD-averaged potential energy grid and a solvent-accessible surface area term with parameters GA fit to experimental data

Proteins, structure, function, and bioinformatics, 2008-05, Vol.71 (3), p.1519-1538

2008

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The Occurrence of Breithauptite and Nisbite-Like Sb-Ni Phases At Sindesar-Khurd, Rajasthan, India: Implications For Melt-Assisted Sulfide Remobilization

Canadian mineralogist, 2017-01, Vol.55 (1), p.75-87

2017

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Phenotypic and Structural Analyses of Hepatitis C Virus NS3 Protease Arg155 Variants

The Journal of biological chemistry, 2007-08, Vol.282 (31), p.22619-22628

2007

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In Vitro Resistance Studies of Hepatitis C Virus Serine Protease Inhibitors, VX-950 and BILN 2061

The Journal of biological chemistry, 2004-04, Vol.279 (17), p.17508-17514

2004

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Inhibitors of hepatitis C virus NS3.4A protease. Part 3: P2 proline variants

Bioorganic & medicinal chemistry letters, 2004-04, Vol.14 (8), p.1939-1942

2004

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Inhibitors of hepatitis C virus NS3.4A protease 2. Warhead SAR and optimization

Bioorganic & medicinal chemistry letters, 2004-03, Vol.14 (6), p.1441-1446

2004

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Improvement of biodiesel methanol blends

Alexandria engineering journal, 2016-06, Vol.55 (2), p.1201-1209

2016

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Preclinical Profile of VX-950, a Potent, Selective, and Orally Bioavailable Inhibitor of Hepatitis C Virus NS3-4A Serine Protease

Effect of injection parameters on the performance and emission characteristics of a variable compression ratio diesel engine with plastic oil blends – An experimental study

In Vitro Phenotypic Characterization of Hepatitis C Virus NS3 Protease Variants Observed in Clinical Studies of Telaprevir

Viral and cellular RNA helicases as antiviral targets

In Vitro Studies of Cross-resistance Mutations against Two Hepatitis C Virus Serine Protease Inhibitors, VX-950 and BILN 2061

Improvement of biodiesel methanol blends performance in a variable compression ratio engine using response surface methodology

Benzimidazole-containing HCV NS5A inhibitors: Effect of 4-substituted pyrrolidines in balancing genotype 1a and 1b potency

Characterization of V36C, a Novel Amino Acid Substitution Conferring Hepatitis C Virus (HCV) Resistance to Telaprevir, a Potent Peptidomimetic Inhibitor of HCV Protease

Heat transfer from a horizontal fin array by natural convection and radiation—A conjugate analysis

Recent developments in the design of specific Matrix Metalloproteinase inhibitors aided by structural and computational studies

Novel thiol-based TACE inhibitors: Rational design, synthesis, and SAR of thiol-containing aryl sulfonamides

Novel thiol-based TACE inhibitors. Part 2: Rational design, synthesis, and SAR of thiol-containing aryl sulfones

In vitro resistance studies of hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061: structural analysis indicates different resistance mechanisms

Genotypic and phenotypic analyses of hepatitis C virus variants observed in clinical studies of VX-222, a nonnucleoside NS5B polymerase inhibitor

Discovery of Novel Thiophene-Based, Thumb Pocket 2 Allosteric Inhibitors of the Hepatitis C NS5B Polymerase with Improved Potency and Physicochemical Profiles

Nonstructural protein 5A (NS5A) and human replication protein A increase the processivity of hepatitis C virus NS5B polymerase activity in vitro

Discovery of Novel Allosteric HCV NS5B Inhibitors. 2. Lactam-Containing Thiophene Carboxylates

Phenotypic Characterization of Resistant Val36 Variants of Hepatitis C Virus NS3-4A Serine Protease

FURSMASA: A new approach to rapid scoring functions that uses a MD-averaged potential energy grid and a solvent-accessible surface area term with parameters GA fit to experimental data

The Occurrence of Breithauptite and Nisbite-Like Sb-Ni Phases At Sindesar-Khurd, Rajasthan, India: Implications For Melt-Assisted Sulfide Remobilization

Phenotypic and Structural Analyses of Hepatitis C Virus NS3 Protease Arg155 Variants

In Vitro Resistance Studies of Hepatitis C Virus Serine Protease Inhibitors, VX-950 and BILN 2061

Inhibitors of hepatitis C virus NS3.4A protease. Part 3: P2 proline variants

Inhibitors of hepatitis C virus NS3.4A protease 2. Warhead SAR and optimization

Improvement of biodiesel methanol blends

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