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Antiviral Drug Strategies. Edited by Erik DeClercq

ChemMedChem, 2012-02, Vol.7 (2), p.334-334

Gosselin, Gilles

2012

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Two-Metal-Ion Catalysis in Adenylyl Cyclase

Science (American Association for the Advancement of Science), 1999-07, Vol.285 (5428), p.756-760

1999

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Antihepatitis B Virus Activity of a Protein-Enriched Fraction from Housefly (Musca domestica) in a Stable HBV-Producing Cell Line

TheScientificWorld, 2014-01, Vol.2014 (2014), p.1-6

2014

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Antiviral l-Nucleosides Specific for Hepatitis B Virus Infection

Antimicrobial Agents and Chemotherapy, 2001-01, Vol.45 (1), p.229-235

2001

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Synthesis of 2′- C-methyl-branched isonucleosides

Tetrahedron, 2008-07, Vol.64 (28), p.6657-6661

2008

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l-Nucleoside enantiomers as antivirals drugs: A mini-review

Antiviral research, 2006-09, Vol.71 (2), p.276-281

2006

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Telbivudine – from the discovery of its antiviral activity to a marketed drug (Tyzeka®, Sebivo®) for the treatment of chronic hepatitis B

Hamdan medical journal (Online), 2014

Gosselin, Gilles

2014

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Pro-nucleotide Inhibitors of Adenylyl Cyclases in Intact Cells

The Journal of biological chemistry, 2004-04, Vol.279 (14), p.13317-13332

2004

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Editorial

Drug discovery today. Technologies, 2012-09, Vol.9 (3), p.e175-e176

2012

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Synthesis and Pharmacokinetics of Valopicitabine (NM283), an Efficient Prodrug of the Potent Anti-HCV Agent 2‘-C-Methylcytidine

Journal of medicinal chemistry, 2006-11, Vol.49 (22), p.6614-6620

2006

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The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2′-α-chloro-2′-β-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors

Bioorganic & medicinal chemistry letters, 2017-09, Vol.27 (18), p.4323-4330

2017

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Rational design for cytosolic delivery of nucleoside monphosphates : “SATE” and “DTE” as enzyme-labile transient phosphate protecting groups

Bioorganic & medicinal chemistry letters, 1993-12, Vol.3 (12), p.2521-2526

1993

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Potentiation of Inhibition of Wild-Type and Mutant Human Immunodeficiency Virus Type 1 Reverse Transcriptases by Combinations of Nonnucleoside Inhibitors and d- and l-(β)-Dideoxynucleoside Triphosphate Analogs

Antimicrobial Agents and Chemotherapy, 2001-04, Vol.45 (4), p.1192-1200

2001

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Inhibition of Adenylyl Cyclase by Acyclic Nucleoside Phosphonate Antiviral Agents

The Journal of biological chemistry, 1999-12, Vol.274 (49), p.34742-34744

1999

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Corrigendum to “Synthesis of unnatural 3′-phospha-2′-deoxyfuranose nucleoside analogues” [Tetrahedron Lett. 55 (2014) 6328–6330]

Tetrahedron letters, 2015-04, Vol.56 (15), p.2035-2035

2015

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Synthesis of Unnatural Phosphonosugar Analogues

European journal of organic chemistry, 2014-02, Vol.2014 (6), p.1333-1337

2014

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Corrigendum to “Synthesis of unnatural 2- and 3-deoxyfuranose analogues” [Tetrahedron Lett. 55 (2014) 3706–3708]

Tetrahedron letters, 2015-04, Vol.56 (15), p.2034-2034

2015

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Synthesis of unnatural 3′-phospha-2′-deoxyfuranose nucleoside analogues

Tetrahedron letters, 2014-11, Vol.55 (46), p.6328-6330

2014

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L-nucleoside enantiomers as antiviral drugs : a mini-review

Antiviral research, 2006, Vol.71, p.276-281

2006

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Structure−Activity Relationships of Uridine 5‘-Diphosphate Analogues at the Human P2Y6 Receptor

Journal of medicinal chemistry, 2006-09, Vol.49 (18), p.5532-5543

2006

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Design, synthesis and antiviral evaluation of 2'-C-methyl branched guanosine pronucleotides: the discovery of IDX184, a potent liver-targeted HCV polymerase inhibitor

Future medicinal chemistry, 2015-09, Vol.7 (13), p.1675-1700

2015

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Synthesis of unnatural 2- and 3-deoxyfuranose analogues

Tetrahedron letters, 2014-07, Vol.55 (27), p.3706-3708

2014

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Substituted benzimidazoles: antiviral activity and synthesis of nucleosides

ARKIVOC free online journal of organic chemistry, 2009-01, Vol.2009 (3), p.225-250

2009

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Synthesis of Nucleoside Analogues Bearing the Five Naturally Occurring Nucleic Acid Bases Built on a 2-Oxabicylo[3.1.0]hexane Scaffold

Journal of organic chemistry, 2005-08, Vol.70 (17), p.6891-6897

2005

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Synthesis of a new family of acyclic nucleoside phosphonates, analogues of TPases transition statesElectronic supplementary information (ESI) available: Copies of the relevant spectra or analyses (1H NMR, 13C NMR, 31P NMR, MS, HRMS). See DOI: 10.1039/c2ob25131k

2012-05

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Antiviral Drug Strategies. Edited by Erik DeClercq

Two-Metal-Ion Catalysis in Adenylyl Cyclase

Antihepatitis B Virus Activity of a Protein-Enriched Fraction from Housefly (Musca domestica) in a Stable HBV-Producing Cell Line

Antiviral l-Nucleosides Specific for Hepatitis B Virus Infection

Synthesis of 2′- C-methyl-branched isonucleosides

l-Nucleoside enantiomers as antivirals drugs: A mini-review

Telbivudine – from the discovery of its antiviral activity to a marketed drug (Tyzeka®, Sebivo®) for the treatment of chronic hepatitis B

Pro-nucleotide Inhibitors of Adenylyl Cyclases in Intact Cells

Editorial

Synthesis and Pharmacokinetics of Valopicitabine (NM283), an Efficient Prodrug of the Potent Anti-HCV Agent 2‘-C-Methylcytidine

The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2′-α-chloro-2′-β-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors

Rational design for cytosolic delivery of nucleoside monphosphates : “SATE” and “DTE” as enzyme-labile transient phosphate protecting groups

Potentiation of Inhibition of Wild-Type and Mutant Human Immunodeficiency Virus Type 1 Reverse Transcriptases by Combinations of Nonnucleoside Inhibitors and d- and l-(β)-Dideoxynucleoside Triphosphate Analogs

Inhibition of Adenylyl Cyclase by Acyclic Nucleoside Phosphonate Antiviral Agents

Corrigendum to “Synthesis of unnatural 3′-phospha-2′-deoxyfuranose nucleoside analogues” [Tetrahedron Lett. 55 (2014) 6328–6330]

Synthesis of Unnatural Phosphonosugar Analogues

Corrigendum to “Synthesis of unnatural 2- and 3-deoxyfuranose analogues” [Tetrahedron Lett. 55 (2014) 3706–3708]

Synthesis of unnatural 3′-phospha-2′-deoxyfuranose nucleoside analogues

L-nucleoside enantiomers as antiviral drugs : a mini-review

Structure−Activity Relationships of Uridine 5‘-Diphosphate Analogues at the Human P2Y6 Receptor

Design, synthesis and antiviral evaluation of 2'-C-methyl branched guanosine pronucleotides: the discovery of IDX184, a potent liver-targeted HCV polymerase inhibitor

Synthesis of unnatural 2- and 3-deoxyfuranose analogues

Substituted benzimidazoles: antiviral activity and synthesis of nucleosides

Synthesis of Nucleoside Analogues Bearing the Five Naturally Occurring Nucleic Acid Bases Built on a 2-Oxabicylo[3.1.0]hexane Scaffold

Synthesis of a new family of acyclic nucleoside phosphonates, analogues of TPases transition statesElectronic supplementary information (ESI) available: Copies of the relevant spectra or analyses (1H NMR, 13C NMR, 31P NMR, MS, HRMS). See DOI: 10.1039/c2ob25131k

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