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Mu Opioid Receptor Antagonists: Recent Developments

ChemMedChem, 2007-11, Vol.2 (11), p.1552-1570

2007

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Development of a Fluorescence Assay for the Characterization of Brevenal Binding to Rat Brain Synaptosomes

Journal of natural products (Washington, D.C.), 2014-09, Vol.77 (9), p.2014-2020

2014

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CB2 selective sulfamoyl benzamides : Optimization of the amide functionality

Bioorganic & medicinal chemistry letters, 2009-01, Vol.19 (2), p.309-313

2009

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Novel pyridine derivatives as potent and selective CB2 cannabinoid receptor agonists

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (20), p.5931-5935

2009

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Synthesis and Pharmacological Evaluation of Novel Octahydro-1H-pyrido[1,2-a]pyrazine as μ-Opioid Receptor Antagonists

Journal of medicinal chemistry, 2006-12, Vol.49 (25), p.7290-7306

2006

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Elucidation of the Bioactive Conformation of the N-Substituted trans-3,4-Dimethyl-4-(3-hydroxyphenyl)piperidine Class of μ-Opioid Receptor Antagonists

Journal of medicinal chemistry, 2006-12, Vol.49 (25), p.7278-7289

2006

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Model Systems for Flavoenzyme Activity: Interplay of Hydrogen Bonding and Aromatic Stacking in Cofactor Redox Modulation

Organic letters, 2004-02, Vol.6 (3), p.385-388

2004

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Comprehensive Survey of Chemical Libraries for Drug Discovery and Chemical Biology: 2008

Journal of combinatorial chemistry, 2009-09, Vol.11 (5), p.739-790

2009

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Model Systems for Flavoenzyme Activity. Control of Flavin Recognition via Specific Electrostatic Interactions

Organic letters, 2001-05, Vol.3 (10), p.1531-1534

2001

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Synthesis and structure–activity relationships of a new series of 2α-substituted trans-4,5-dimethyl-4-(3-hydroxyphenyl)piperidine as μ-selective opioid antagonists

Bioorganic & medicinal chemistry letters, 2006-02, Vol.16 (4), p.864-868

2006

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Comprehensive Survey of Chemical Libraries for Drug Discovery and Chemical Biology: 2007

Journal of combinatorial chemistry, 2008-11, Vol.10 (6), p.753-802

2008

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Comprehensive Survey of Chemical Libraries for Drug Discovery and Chemical Biology: 2006

Journal of combinatorial chemistry, 2007-11, Vol.9 (6), p.855-902

2007

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Novel pyridine derivatives as potent and selective CB sub(2) cannabinoid receptor agonists

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (20), p.5931-5935

2009

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Synthesis and Pharmacological Evaluation of Novel Octahydro-1 H -pyrido[1,2-a]pyrazine as μ-Opioid Receptor Antagonists

Journal of medicinal chemistry, 2006-12, Vol.49 (25), p.7290-7306

2006

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Novel pyridine derivatives as potent and selective CB 2 cannabinoid receptor agonists

Bioorganic & medicinal chemistry letters, 2009, Vol.19 (20), p.5931-5935

2009

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Desymmetrization of dichloroazaheterocycles

Tetrahedron, 1999-12, Vol.55 (52), p.15067-15070

1999

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CB 2 selective sulfamoyl benzamides: Optimization of the amide functionality

Bioorganic & medicinal chemistry letters, 2009, Vol.19 (2), p.309-313

2009

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Synthesis and structure-activity relationships of a new series of 2alpha-substituted trans-4,5-dimethyl-4-(3-hydroxyphenyl)piperidine as mu-selective opioid antagonists

Bioorganic & medicinal chemistry letters, 2006-02, Vol.16 (4), p.864-868

2006

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ChemInform Abstract: Mu Opioid Receptor Antagonists: Recent Developments

ChemInform, 2008-02, Vol.39 (6), p.no-no

2008

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ChemInform Abstract: Comprehensive Survey of Chemical Libraries for Drug Discovery and Chemical Biology: 2008

ChemInform, 2010-01, Vol.41 (2), p.no-no

2010

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ChemInform Abstract: Comprehensive Survey of Chemical Libraries for Drug Discovery and Chemical Biology: 2007

ChemInform, 2009-02, Vol.40 (7), p.no-no

2009

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ChemInform Abstract: Comprehensive Survey of Chemical Libraries for Drug Discovery and Chemical Biology: 2006

ChemInform, 2008-03, Vol.39 (13), p.no-no

2008

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ChemInform Abstract: Desymmetrization of Dichloroazaheterocycles

ChemInform, 2000-03, Vol.31 (13), p.no-no

2000

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Synthesis and Structure-Activity Relationships of a New Series of 2α-Substituted trans-4,5-Dimethyl-4-(3-hydroxyphenyl)piperidines as μ-Selective Opioid Antagonists

ChemInform, 2006-05, Vol.37 (19), p.no-no

2006

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High-dose cyclophosphamide as single-agent, short-course prophylaxis of graft-versus-host disease

Blood, 2010-04, Vol.115 (16), p.3224-3230

2010

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Mu Opioid Receptor Antagonists: Recent Developments

Development of a Fluorescence Assay for the Characterization of Brevenal Binding to Rat Brain Synaptosomes

CB2 selective sulfamoyl benzamides : Optimization of the amide functionality

Novel pyridine derivatives as potent and selective CB2 cannabinoid receptor agonists

Synthesis and Pharmacological Evaluation of Novel Octahydro-1H-pyrido[1,2-a]pyrazine as μ-Opioid Receptor Antagonists

Elucidation of the Bioactive Conformation of the N-Substituted trans-3,4-Dimethyl-4-(3-hydroxyphenyl)piperidine Class of μ-Opioid Receptor Antagonists

Model Systems for Flavoenzyme Activity: Interplay of Hydrogen Bonding and Aromatic Stacking in Cofactor Redox Modulation

Comprehensive Survey of Chemical Libraries for Drug Discovery and Chemical Biology: 2008

Model Systems for Flavoenzyme Activity. Control of Flavin Recognition via Specific Electrostatic Interactions

Synthesis and structure–activity relationships of a new series of 2α-substituted trans-4,5-dimethyl-4-(3-hydroxyphenyl)piperidine as μ-selective opioid antagonists

Comprehensive Survey of Chemical Libraries for Drug Discovery and Chemical Biology: 2007

Comprehensive Survey of Chemical Libraries for Drug Discovery and Chemical Biology: 2006

Novel pyridine derivatives as potent and selective CB sub(2) cannabinoid receptor agonists

Synthesis and Pharmacological Evaluation of Novel Octahydro-1 H -pyrido[1,2-a]pyrazine as μ-Opioid Receptor Antagonists

Novel pyridine derivatives as potent and selective CB 2 cannabinoid receptor agonists

Desymmetrization of dichloroazaheterocycles

CB 2 selective sulfamoyl benzamides: Optimization of the amide functionality

Synthesis and structure-activity relationships of a new series of 2alpha-substituted trans-4,5-dimethyl-4-(3-hydroxyphenyl)piperidine as mu-selective opioid antagonists

ChemInform Abstract: Mu Opioid Receptor Antagonists: Recent Developments

ChemInform Abstract: Comprehensive Survey of Chemical Libraries for Drug Discovery and Chemical Biology: 2008

ChemInform Abstract: Comprehensive Survey of Chemical Libraries for Drug Discovery and Chemical Biology: 2007

ChemInform Abstract: Comprehensive Survey of Chemical Libraries for Drug Discovery and Chemical Biology: 2006

ChemInform Abstract: Desymmetrization of Dichloroazaheterocycles

Synthesis and Structure-Activity Relationships of a New Series of 2α-Substituted trans-4,5-Dimethyl-4-(3-hydroxyphenyl)piperidines as μ-Selective Opioid Antagonists

High-dose cyclophosphamide as single-agent, short-course prophylaxis of graft-versus-host disease

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