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Tissue-type plasminogen activator selectively inhibits multiple toll-like receptors in CSF-1-differentiated macrophages

PloS one, 2019-11, Vol.14 (11), p.e0224738-e0224738

2019

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LDL receptor-related protein-1 regulates NFκB and microRNA-155 in macrophages to control the inflammatory response

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (5), p.1369-1374

2016

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Plasminogen Receptors in Human Malignancies: Effects on Prognosis and Feasibility as Targets for Drug Development

Current drug targets, 2020-01, Vol.21 (7), p.647

2020

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Shedding of membrane-associated LDL receptor-related protein-1 from microglia amplifies and sustains neuroinflammation

The Journal of biological chemistry, 2017-11, Vol.292 (45), p.18699-18712

2017

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LRP1 deficiency in microglia blocks neuro‐inflammation in the spinal dorsal horn and neuropathic pain processing

Glia, 2019-06, Vol.67 (6), p.1210-1224

2019

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Expression of LDL receptor-related proteins (LRPs) in common solid malignancies correlates with patient survival

PloS one, 2017-10, Vol.12 (10), p.e0186649-e0186649

2017

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High-resolution imaging of the dynamic tumor cell-vascular interface in transparent zebrafish

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (44), p.17406-17411

2007

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Tissue-type plasminogen activator regulates macrophage activation and innate immunity

Blood, 2017-09, Vol.130 (11), p.1364-1374

2017

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The LRP1/CD91 ligands, tissue-type plasminogen activator, α2-macroglobulin, and soluble cellular prion protein have distinct co-receptor requirements for activation of cell-signaling

Scientific reports, 2022-10, Vol.12 (1), p.17594-17594, Article 17594

2022

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Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages

Journal of leukocyte biology, 2010-10, Vol.88 (4), p.769-778

2010

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Chemoattractant signaling between tumor cells and macrophages regulates cancer cell migration, metastasis and neovascularization

PloS one, 2009-08, Vol.4 (8), p.e6713-e6713

2009

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Urokinase receptor and resistance to targeted anticancer agents

Frontiers in pharmacology, 2015-07, Vol.6, p.154-154

2015

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Reversibility of Epithelial-Mesenchymal Transition (EMT) Induced in Breast Cancer Cells by Activation of Urokinase Receptor-dependent Cell Signaling

The Journal of biological chemistry, 2009-08, Vol.284 (34), p.22825-22833

2009

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uPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells

The Journal of cell biology, 2007-07, Vol.178 (3), p.425-436

2007

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Plasminogen activator receptor assemblies in cell signaling, innate immunity, and inflammation

American Journal of Physiology: Cell Physiology, 2021-10, Vol.321 (4), p.C721-C734

Gonias, Steven L.

2021

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A urokinase receptor-Bim signaling axis emerges during EGFR inhibitor resistance in mutant EGFR glioblastoma

Cancer research (Chicago, Ill.), 2015-01, Vol.75 (2), p.394-404

2015

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The Hemopexin Domain of Matrix Metalloproteinase-9 Activates Cell Signaling and Promotes Migration of Schwann Cells by Binding to Low-Density Lipoprotein Receptor-Related Protein

The Journal of neuroscience, 2008-11, Vol.28 (45), p.11571-11582

2008

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Mammalian target of rapamycin complex 2 (mTORC2) is a critical determinant of bladder cancer invasion

PloS one, 2013-11, Vol.8 (11), p.e81081-e81081

2013

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Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines

Journal of neuroinflammation, 2019-12, Vol.16 (1), p.257-257, Article 257

2019

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Cell Signaling by Urokinase-type Plasminogen Activator Receptor Induces Stem Cell―like Properties in Breast Cancer Cells

Cancer research (Chicago, Ill.), 2010-11, Vol.70 (21), p.8948-8958

2010

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Schwann cell extracellular vesicles: judging a book by its cover

Neural regeneration research, 2023-02, Vol.18 (2), p.325-326

2023

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Pertussis Toxin Is a Robust and Selective Inhibitor of High Grade Glioma Cell Migration and Invasion

PloS one, 2016-12, Vol.11 (12), p.e0168418-e0168418

2016

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Ligand binding to LRP1 transactivates Trk receptors by a Src family kinase-dependent pathway

Science signaling, 2009-04, Vol.2 (68), p.ra18

2009

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Mechanisms by Which LRP1 (Low-Density Lipoprotein Receptor-Related Protein-1) Maintains Arterial Integrity

Arteriosclerosis, thrombosis, and vascular biology, 2018-11, Vol.38 (11), p.2548

Gonias, Steven L

2018

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Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells

Proceedings of the National Academy of Sciences - PNAS, 2011-09, Vol.108 (38), p.15984-15989

2011

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Tissue-type plasminogen activator selectively inhibits multiple toll-like receptors in CSF-1-differentiated macrophages

LDL receptor-related protein-1 regulates NFκB and microRNA-155 in macrophages to control the inflammatory response

Plasminogen Receptors in Human Malignancies: Effects on Prognosis and Feasibility as Targets for Drug Development

Shedding of membrane-associated LDL receptor-related protein-1 from microglia amplifies and sustains neuroinflammation

LRP1 deficiency in microglia blocks neuro‐inflammation in the spinal dorsal horn and neuropathic pain processing

Expression of LDL receptor-related proteins (LRPs) in common solid malignancies correlates with patient survival

High-resolution imaging of the dynamic tumor cell-vascular interface in transparent zebrafish

Tissue-type plasminogen activator regulates macrophage activation and innate immunity

The LRP1/CD91 ligands, tissue-type plasminogen activator, α2-macroglobulin, and soluble cellular prion protein have distinct co-receptor requirements for activation of cell-signaling

Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages

Chemoattractant signaling between tumor cells and macrophages regulates cancer cell migration, metastasis and neovascularization

Urokinase receptor and resistance to targeted anticancer agents

Reversibility of Epithelial-Mesenchymal Transition (EMT) Induced in Breast Cancer Cells by Activation of Urokinase Receptor-dependent Cell Signaling

uPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells

Plasminogen activator receptor assemblies in cell signaling, innate immunity, and inflammation

A urokinase receptor-Bim signaling axis emerges during EGFR inhibitor resistance in mutant EGFR glioblastoma

The Hemopexin Domain of Matrix Metalloproteinase-9 Activates Cell Signaling and Promotes Migration of Schwann Cells by Binding to Low-Density Lipoprotein Receptor-Related Protein

Mammalian target of rapamycin complex 2 (mTORC2) is a critical determinant of bladder cancer invasion

Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines

Cell Signaling by Urokinase-type Plasminogen Activator Receptor Induces Stem Cell―like Properties in Breast Cancer Cells

Schwann cell extracellular vesicles: judging a book by its cover

Pertussis Toxin Is a Robust and Selective Inhibitor of High Grade Glioma Cell Migration and Invasion

Ligand binding to LRP1 transactivates Trk receptors by a Src family kinase-dependent pathway

Mechanisms by Which LRP1 (Low-Density Lipoprotein Receptor-Related Protein-1) Maintains Arterial Integrity

Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells

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