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mSphere of Influence: Expanding the CRISPR Sphere with Single-Locus Proteomics

mSphere, 2020-01, Vol.5 (1)

Glover, Lucy

2020

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DNA break site at fragile subtelomeres determines probability and mechanism of antigenic variation in African trypanosomes

PLoS pathogens, 2013-03, Vol.9 (3), p.e1003260-e1003260

2013

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Monoallelic expression and epigenetic inheritance sustained by a Trypanosoma brucei variant surface glycoprotein exclusion complex

Nature communications, 2019-07, Vol.10 (1), p.3023-14, Article 3023

2019

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High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome

Genome research, 2011-06, Vol.21 (6), p.915-924

2011

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High-throughput decoding of antitrypanosomal drug efficacy and resistance

Nature (London), 2012-02, Vol.482 (7384), p.232-236

2012

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Insights into antitrypanosomal drug mode-of-action from cytology-based profiling

PLoS neglected tropical diseases, 2018-11, Vol.12 (11), p.e0006980

2018

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Single-cell transcriptomics reveals expression profiles of Trypanosoma brucei sexual stages

PLoS pathogens, 2022-03, Vol.18 (3), p.e1010346-e1010346

2022

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Microhomology-mediated deletion and gene conversion in African trypanosomes

Nucleic acids research, 2011-03, Vol.39 (4), p.1372-1380

2011

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DNA double strand break position leads to distinct gene expression changes and regulates VSG switching pathway choice

PLoS pathogens, 2021-11, Vol.17 (11), p.e1010038-e1010038

2021

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Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (27), p.10996-11001

2012

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Genome-wide RNAi selection identifies a regulator of transmission stage-enriched gene families and cell-type differentiation in Trypanosoma brucei

PLoS pathogens, 2017-03, Vol.13 (3), p.e1006279-e1006279

2017

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Persistent DNA Damage Foci and DNA Replication with a Broken Chromosome in the African Trypanosome

mBio, 2019-07, Vol.10 (4), p.e01252-19

2019

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Transcription Dependent Loss of an Ectopically Expressed Variant Surface Glycoprotein during Antigenic Variation in Trypanosoma brucei

mBio, 2022-04, Vol.13 (2), p.e0384721-e0384721

2022

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Escaping the immune system by DNA repair and recombination in African trypanosomes

Open biology, 2019-11, Vol.9 (11), p.190182-190182

2019

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Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome

PLoS neglected tropical diseases, 2023-02, Vol.17 (2), p.e0011093

2023

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PPL2 Translesion Polymerase Is Essential for the Completion of Chromosomal DNA Replication in the African Trypanosome

Molecular cell, 2013-11, Vol.52 (4), p.554-565

2013

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Trypanosomal histone γH2A and the DNA damage response

Molecular and biochemical parasitology, 2012-05, Vol.183 (1), p.78-83

2012

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VEX1 Influences mVSG Expression During the Transition to Mammalian Infectivity in Trypanosoma brucei

Frontiers in cell and developmental biology, 2022-04, Vol.10, p.851475-851475

2022

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Forward Genetics in African Trypanosomes

Methods in molecular biology (Clifton, N.J.), 2020, Vol.2116, p.339

2020

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Locus-specific control of DNA resection and suppression of subtelomeric VSG recombination by HAT3 in the African trypanosome

Nucleic acids research, 2014-11, Vol.42 (20), p.12600-12613

2014

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VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes

Proceedings of the National Academy of Sciences - PNAS, 2016-06, Vol.113 (26), p.7225-7230

2016

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High-resolution analysis of multi-copy variant surface glycoprotein gene expression sites in African trypanosomes

BMC genomics, 2016-10, Vol.17 (1), p.806-806, Article 806

2016

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A post-transcriptional respiratome regulon in trypanosomes

Nucleic acids research, 2019-07, Vol.47 (13), p.7063-7077

2019

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CRISPR in Parasitology: Not Exactly Cut and Dried

Trends in parasitology, 2019-06, Vol.35 (6), p.409-422

2019

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mSphere of Influence: Expanding the CRISPR Sphere with Single-Locus Proteomics

DNA break site at fragile subtelomeres determines probability and mechanism of antigenic variation in African trypanosomes

Monoallelic expression and epigenetic inheritance sustained by a Trypanosoma brucei variant surface glycoprotein exclusion complex

High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome

High-throughput decoding of antitrypanosomal drug efficacy and resistance

Insights into antitrypanosomal drug mode-of-action from cytology-based profiling

Single-cell transcriptomics reveals expression profiles of Trypanosoma brucei sexual stages

Microhomology-mediated deletion and gene conversion in African trypanosomes

DNA double strand break position leads to distinct gene expression changes and regulates VSG switching pathway choice

Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes

Genome-wide RNAi selection identifies a regulator of transmission stage-enriched gene families and cell-type differentiation in Trypanosoma brucei

Persistent DNA Damage Foci and DNA Replication with a Broken Chromosome in the African Trypanosome

Transcription Dependent Loss of an Ectopically Expressed Variant Surface Glycoprotein during Antigenic Variation in Trypanosoma brucei

Escaping the immune system by DNA repair and recombination in African trypanosomes

Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome

PPL2 Translesion Polymerase Is Essential for the Completion of Chromosomal DNA Replication in the African Trypanosome

Trypanosomal histone γH2A and the DNA damage response

Specificity of serological screening tests and reference laboratory tests to diagnose gambiense human African trypanosomiasis: a prospective clinical performance study

VEX1 Influences mVSG Expression During the Transition to Mammalian Infectivity in Trypanosoma brucei

Forward Genetics in African Trypanosomes

Locus-specific control of DNA resection and suppression of subtelomeric VSG recombination by HAT3 in the African trypanosome

VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes

High-resolution analysis of multi-copy variant surface glycoprotein gene expression sites in African trypanosomes

A post-transcriptional respiratome regulon in trypanosomes

CRISPR in Parasitology: Not Exactly Cut and Dried

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