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The Primo Vascular System as a Possible Exosomal Route Across the Body: Implications for Tumor Proliferation and Metastasis

Journal of Acupuncture & Meridian Studies, 2019, 12(1), 57, pp.25-28

Ghiron, Chiara

2019

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KIF11 inhibition for glioblastoma treatment: reason to hope or a struggle with the brain?

BMC cancer, 2009-06, Vol.9 (1), p.196-196, Article 196

2009

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Scaffold Preparation and Parallel Synthesis of Arrays of 5,6,7,8-Tetrahydropyrrolo-azepinones in the Solution Phase

European Journal of Organic Chemistry, 2008-06, Vol.2008 (16), p.2789-2800

2008

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A Practical Synthesis of 2,4(5)-Diarylimidazoles from Simple Building Blocks

Journal of organic chemistry, 2007-06, Vol.72 (12), p.4551-4553

2007

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Microwave-Assisted Hydrogenation of Pyridines

Synlett, 2008-05, Vol.2008 (8), p.1125-1128

2008

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Procognitive and Neuroprotective Activity of a Novel α7 Nicotinic Acetylcholine Receptor Agonist for Treatment of Neurodegenerative and Cognitive Disorders

The Journal of pharmacology and experimental therapeutics, 2009-05, Vol.329 (2), p.459-468

2009

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Übungen zur organischen Synthese

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Design and synthesis of a hybrid series of potent and selective agonists of α7 nicotinic acetylcholine receptor

European journal of medicinal chemistry, 2014-05, Vol.78, p.401-418

2014

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Discovery of a Novel Alpha-7 Nicotinic Acetylcholine Receptor Agonist Series and Characterization of the Potent, Selective, and Orally Efficacious Agonist 5-(4-Acetyl[1,4]diazepan-1-yl)pentanoic Acid [5-(4-Methoxyphenyl)-1H-pyrazol-3-yl] Amide (SEN15924, WAY-361789)

Journal of medicinal chemistry, 2012-05, Vol.55 (10), p.4806-4823

2012

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Ubungen zur organischen Synthese

1999 edition, 2013

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Microwave-assisted synthesis of tetrahydroindoles

Tetrahedron letters, 2008-01, Vol.49 (3), p.459-462

2008

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Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein-Protein Interaction by a Scaffold-Hopping Approach

Chemical biology & drug design, 2015-08, Vol.86 (2), p.180-189

2015

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SAR and biological evaluation of SEN12333/WAY-317538: Novel alpha 7 nicotinic acetylcholine receptor agonist

Bioorganic & medicinal chemistry, 2009-07, Vol.17 (14), p.5247-5258

2009

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Aryl azoles with neuroprotective activity—Parallel synthesis and attempts at target identification

Bioorganic & medicinal chemistry, 2008-02, Vol.16 (4), p.2043-2052

2008

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N‑[5-(5-Fluoropyridin-3-yl)‑1H‑pyrazol-3-yl]-4-piperidin-1-ylbutyramide (SEN78702, WYE-308775): A Medicinal Chemistry Effort toward an α7 Nicotinic Acetylcholine Receptor Agonist Preclinical Candidate

Journal of medicinal chemistry, 2012-11, Vol.55 (22), p.10277-10281

2012

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Analogues of 4,5-bis(3,5-dichlorophenyl)-2-trifluoromethyl-1H-imidazole as potential antibacterial agents

Bioorganic & medicinal chemistry letters, 1999-04, Vol.9 (7), p.1023-1028

1999

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Synthesis of Novel 4-Fluoro-2H-pyrazol-3-ylamines

Synthetic communications, 2010-08, Vol.40 (17), p.2547-2555

2010

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Preclinical assessment of an adjunctive treatment approach for cognitive impairment associated with schizophrenia using the alpha7 nicotinic acetylcholine receptor agonist WYE-103914/SEN34625

Psychopharmacologia, 2011-12, Vol.218 (4), p.635-647

2011

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Searching for Dual Inhibitors of the MDM 2‐p53 and MDMX ‐p53 Protein–Protein Interaction by a Scaffold‐Hopping Approach

Chemical biology & drug design, 2015-08, Vol.86 (2), p.180-189

2015

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Übungen zur organischen Synthese

1999

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Simplified Analogues of Immucillin-G Retain Potent Human Purine Nucleoside Phosphorylase Inhibitory Activity

Journal of medicinal chemistry, 2006-10, Vol.49 (20), p.6037-6045

2006

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2,4(5)-Diarylimidazoles as inhibitors of hNav1.2 sodium channels: Pharmacological evaluation and structure-property relationships

Bioorganic & medicinal chemistry, 2009-05, Vol.17 (10), p.3642-3648

2009

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2,4(5)-Diarylimidazoles: synthesis and biological evaluation of a new class of sodium channel blockers against hNa(v)1.2

Bioorganic & medicinal chemistry letters, 2008-10, Vol.18 (20), p.5460-5462

2008

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The Primo Vascular System as a Possible Exosomal Route Across the Body: Implications for Tumor Proliferation and Metastasis

KIF11 inhibition for glioblastoma treatment: reason to hope or a struggle with the brain?

Scaffold Preparation and Parallel Synthesis of Arrays of 5,6,7,8-Tetrahydropyrrolo-azepinones in the Solution Phase

A Practical Synthesis of 2,4(5)-Diarylimidazoles from Simple Building Blocks

Microwave-Assisted Hydrogenation of Pyridines

Procognitive and Neuroprotective Activity of a Novel α7 Nicotinic Acetylcholine Receptor Agonist for Treatment of Neurodegenerative and Cognitive Disorders

Übungen zur organischen Synthese

Design and synthesis of a hybrid series of potent and selective agonists of α7 nicotinic acetylcholine receptor

Discovery of a Novel Alpha-7 Nicotinic Acetylcholine Receptor Agonist Series and Characterization of the Potent, Selective, and Orally Efficacious Agonist 5-(4-Acetyl[1,4]diazepan-1-yl)pentanoic Acid [5-(4-Methoxyphenyl)-1H-pyrazol-3-yl] Amide (SEN15924, WAY-361789)

Ubungen zur organischen Synthese

Microwave-assisted synthesis of tetrahydroindoles

Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein-Protein Interaction by a Scaffold-Hopping Approach

SAR and biological evaluation of SEN12333/WAY-317538: Novel alpha 7 nicotinic acetylcholine receptor agonist

Aryl azoles with neuroprotective activity—Parallel synthesis and attempts at target identification

N‑[5-(5-Fluoropyridin-3-yl)‑1H‑pyrazol-3-yl]-4-piperidin-1-ylbutyramide (SEN78702, WYE-308775): A Medicinal Chemistry Effort toward an α7 Nicotinic Acetylcholine Receptor Agonist Preclinical Candidate

Analogues of 4,5-bis(3,5-dichlorophenyl)-2-trifluoromethyl-1H-imidazole as potential antibacterial agents

Synthesis of Novel 4-Fluoro-2H-pyrazol-3-ylamines

Preclinical assessment of an adjunctive treatment approach for cognitive impairment associated with schizophrenia using the alpha7 nicotinic acetylcholine receptor agonist WYE-103914/SEN34625

Structure-Based Design of Novel 2-Amino-6-phenyl-pyrimido[5′,4′:5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as Potent and Orally Active Inhibitors of Lymphocyte Specific Kinase (Lck): Synthesis, SAR, and In Vivo Anti-Inflammatory Activity

Novel Alpha-7 Nicotinic Acetylcholine Receptor Agonists Containing a Urea Moiety: Identification and Characterization of the Potent, Selective, and Orally Efficacious Agonist 1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) Urea (SEN34625/WYE-103914)

Searching for Dual Inhibitors of the MDM 2‐p53 and MDMX ‐p53 Protein–Protein Interaction by a Scaffold‐Hopping Approach

Übungen zur organischen Synthese

Simplified Analogues of Immucillin-G Retain Potent Human Purine Nucleoside Phosphorylase Inhibitory Activity

2,4(5)-Diarylimidazoles as inhibitors of hNav1.2 sodium channels: Pharmacological evaluation and structure-property relationships

2,4(5)-Diarylimidazoles: synthesis and biological evaluation of a new class of sodium channel blockers against hNa(v)1.2

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