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Metabolomics analysis of metabolic effects of nicotinamide phosphoribosyltransferase (NAMPT) inhibition on human cancer cells

PloS one, 2014-12, Vol.9 (12), p.e114019-e114019

2014

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12-O-deacetyl-phomoxanthone A inhibits ovarian tumor growth and metastasis by downregulating PDK4

Biomedicine & pharmacotherapy, 2024-06, Vol.175, p.116736, Article 116736

2024

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Identification of Penexanthone A as a Novel Chemosensitizer to Induce Ferroptosis by Targeting Nrf2 in Human Colorectal Cancer Cells

Marine drugs, 2024-08, Vol.22 (8), p.357

2024

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Dicer Is Required for Embryonic Angiogenesis during Mouse Development

The Journal of biological chemistry, 2005-03, Vol.280 (10), p.9330-9335

2005

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Discovery of a Highly Selective NAMPT Inhibitor That Demonstrates Robust Efficacy and Improved Retinal Toxicity with Nicotinic Acid Coadministration

Molecular cancer therapeutics, 2017-12, Vol.16 (12), p.2677-2688

2017

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Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, Leads to Altered Carbohydrate Metabolism in Cancer Cells

The Journal of biological chemistry, 2015-06, Vol.290 (25), p.15812-15824

2015

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BOCILLIN FL, a Sensitive and Commercially Available Reagent for Detection of Penicillin-Binding Proteins

Antimicrobial Agents and Chemotherapy, 1999-05, Vol.43 (5), p.1124-1128

1999

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Acyl Carrier Protein Synthases from Gram-Negative, Gram-Positive, and Atypical Bacterial Species: Biochemical and Structural Properties and Physiological Implications

Journal of Bacteriology, 2006-07, Vol.188 (13), p.4737-4748

2006

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Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, in Human Cancer Cells

The Journal of biological chemistry, 2013-02, Vol.288 (5), p.3500-3511

2013

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Identification and characterization of an inhibitor specific to bacterial NAD⁺-dependent DNA ligases

The FEBS journal, 2008-11, Vol.275 (21), p.5258-5271

2008

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Derivatization of the tricarboxylic acid intermediates with O-benzylhydroxylamine for liquid chromatography–tandem mass spectrometry detection

Analytical biochemistry, 2014-11, Vol.465, p.134-147

2014

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Small interfering RNA molecules as potential anti-human rhinovirus agents: in vitro potency, specificity, and mechanism

Antiviral research, 2004, Vol.61 (1), p.49-55

2004

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Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential clinical implications

The Journal of biological chemistry, 2013-02, Vol.288 (5), p.3500-3511

2013

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A novel, selective inhibitor of fibroblast growth factor receptors that shows a potent broad spectrum of antitumor activity in several tumor xenograft models

Molecular cancer therapeutics, 2011-11, Vol.10 (11), p.2200-2210

2011

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Abstract 1961: Discovery of a highly potent and brain penetrant fourth generation EGFR tyrosine kinase inhibitor

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.1961-1961

2024

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Abstract 1968: Discovery of a highly potent and selective FGFR2 inhibitor for FGFR2-driven cancers

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.1968-1968

2024

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Abstract 5947: Discovery of ACE-47228211, a highly potent and selective SOS1 inhibitor

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.5947-5947

2024

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Development of a fluorescence resonance energy transfer assay for measuring the activity of Streptococcus pneumoniae DNA ligase, an enzyme essential for DNA replication, repair, and recombination

Analytical biochemistry, 2002-10, Vol.309 (2), p.232-240

2002

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Abstract 4525: Discovery of a highly potent and selective PARP1 inhibitor with superior PK and safety profiles

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.4525-4525

2024

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Gene Disruption Studies of Penicillin-Binding Proteins 1a, 1b, and 2a in Streptococcus pneumoniae

Journal of Bacteriology, 1999-10, Vol.181 (20), p.6552-6555

1999

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Biochemical and Molecular Analyses of the Streptococcus pneumoniae Acyl Carrier Protein Synthase, an Enzyme Essential for Fatty Acid Biosynthesis

The Journal of biological chemistry, 2000-10, Vol.275 (40), p.30864-30872

2000

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Metabolomics Analysis of Metabolic Effects of Nicotinamide Phosphoribosyltransferase

PloS one, 2014-12, Vol.9 (12)

2014

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Era GTPase of Escherichia coli: binding to 16S rRNA and modulation of GTPase activity by RNA and carbohydrates

Microbiology (Society for General Microbiology), 2000-05, Vol.146 ( Pt 5) (5), p.1071-1083

2000

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Pseudomonas aeruginosa Possesses Homologues of Mammalian Phenylalanine Hydroxylase and 4α-Carbinolamine Dehydratase/DCoH as Part of a Three-Component Gene Cluster

Proceedings of the National Academy of Sciences - PNAS, 1994-02, Vol.91 (4), p.1366-1370

1994

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Abstract A24: Beta-klotho expression is associated with the antitumor activity of pan-FGFR inhibitor in human malignancies with FGF19 amplification

Molecular cancer therapeutics, 2015-12, Vol.14 (12_Supplement_2), p.A24-A24

2015

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Metabolomics analysis of metabolic effects of nicotinamide phosphoribosyltransferase (NAMPT) inhibition on human cancer cells

12-O-deacetyl-phomoxanthone A inhibits ovarian tumor growth and metastasis by downregulating PDK4

Identification of Penexanthone A as a Novel Chemosensitizer to Induce Ferroptosis by Targeting Nrf2 in Human Colorectal Cancer Cells

Dicer Is Required for Embryonic Angiogenesis during Mouse Development

Discovery of a Highly Selective NAMPT Inhibitor That Demonstrates Robust Efficacy and Improved Retinal Toxicity with Nicotinic Acid Coadministration

Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, Leads to Altered Carbohydrate Metabolism in Cancer Cells

BOCILLIN FL, a Sensitive and Commercially Available Reagent for Detection of Penicillin-Binding Proteins

Acyl Carrier Protein Synthases from Gram-Negative, Gram-Positive, and Atypical Bacterial Species: Biochemical and Structural Properties and Physiological Implications

Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, in Human Cancer Cells

Identification and characterization of an inhibitor specific to bacterial NAD⁺-dependent DNA ligases

Derivatization of the tricarboxylic acid intermediates with O-benzylhydroxylamine for liquid chromatography–tandem mass spectrometry detection

Small interfering RNA molecules as potential anti-human rhinovirus agents: in vitro potency, specificity, and mechanism

Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential clinical implications

A novel, selective inhibitor of fibroblast growth factor receptors that shows a potent broad spectrum of antitumor activity in several tumor xenograft models

Abstract 1961: Discovery of a highly potent and brain penetrant fourth generation EGFR tyrosine kinase inhibitor

Abstract 1968: Discovery of a highly potent and selective FGFR2 inhibitor for FGFR2-driven cancers

Abstract 5947: Discovery of ACE-47228211, a highly potent and selective SOS1 inhibitor

Development of a fluorescence resonance energy transfer assay for measuring the activity of Streptococcus pneumoniae DNA ligase, an enzyme essential for DNA replication, repair, and recombination

Abstract 4525: Discovery of a highly potent and selective PARP1 inhibitor with superior PK and safety profiles

Gene Disruption Studies of Penicillin-Binding Proteins 1a, 1b, and 2a in Streptococcus pneumoniae

Biochemical and Molecular Analyses of the Streptococcus pneumoniae Acyl Carrier Protein Synthase, an Enzyme Essential for Fatty Acid Biosynthesis

Metabolomics Analysis of Metabolic Effects of Nicotinamide Phosphoribosyltransferase

Era GTPase of Escherichia coli: binding to 16S rRNA and modulation of GTPase activity by RNA and carbohydrates

Pseudomonas aeruginosa Possesses Homologues of Mammalian Phenylalanine Hydroxylase and 4α-Carbinolamine Dehydratase/DCoH as Part of a Three-Component Gene Cluster

Abstract A24: Beta-klotho expression is associated with the antitumor activity of pan-FGFR inhibitor in human malignancies with FGF19 amplification

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