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The Spiroindolone Drug Candidate NITD609 Potently Inhibits Gametocytogenesis and Blocks Plasmodium falciparum Transmission to Anopheles Mosquito Vector

Antimicrobial Agents and Chemotherapy, 2012-07, Vol.56 (7), p.3544-3548

2012

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A Pfs48/45-based vaccine to block Plasmodium falciparum transmission: phase 1, open-label, clinical trial

BMC medicine, 2024-04, Vol.22 (1), p.170-170, Article 170

2024

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Reduced Plasmodium berghei sporozoite liver load associates with low protective efficacy after intradermal immunization

Parasite immunology, 2012-12, Vol.34 (12), p.562-569

2012

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Inhibition of Plasmodium falciparum Oocyst Production by Membrane-Permeant Cysteine Protease Inhibitor E64d

Antimicrobial Agents and Chemotherapy, 2007-03, Vol.51 (3), p.1064-1070

2007

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A Central Role for P48/45 in Malaria Parasite Male Gamete Fertility

Cell, 2001-01, Vol.104 (1), p.153-164

2001

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A combination of new screening assays for prioritization of transmission-blocking antimalarials reveals distinct dynamics of marketed and experimental drugs

Journal of antimicrobial chemotherapy, 2015-05, Vol.70 (5), p.1357-1366

2015

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Leukocytes in a Plasmodium falciparum-infected blood meal reduce transmission of malaria to Anopheles mosquitoes

Infection and Immunity, 1997-09, Vol.65 (9), p.3834-3837

1997

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Precise Timing of Expression of a Plasmodium falciparum- derived Transgene in Plasmodium berghei Is a Critical Determinant of Subsequent Subcellular Localization

The Journal of biological chemistry, 1998-06, Vol.273 (24), p.15119-15124

1998

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A Role for Apical Membrane Antigen 1 during Invasion of Hepatocytes by Plasmodium falciparum Sporozoites

The Journal of biological chemistry, 2004-03, Vol.279 (10), p.9490-9496

2004

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Plasmodium falciparum:Infectivity of Cultured, Synchronized Gametocytes to Mosquitoes

Experimental parasitology, 1999-01, Vol.91 (1), p.101-103

1999

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Functional Equivalence of Structurally Distinct Ribosomes in the Malaria Parasite, Plasmodium berghei

The Journal of biological chemistry, 2001-06, Vol.276 (25), p.22638-22647

2001

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Feeding behaviour and sporozoite ejection by infected Anopheles stephensi

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1991, Vol.85 (2), p.175-180

1991

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Infectivity of cultured Plasmodium falciparum gametocytes to mosquitoes

Parasitology, 1989-04, Vol.98 Pt 2 (2), p.165-173

1989

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High efficiency transfection of Plasmodium berghei facilitates novel selection procedures

Molecular and biochemical parasitology, 2006, Vol.145 (1), p.60-70

2006

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Genetics of refractoriness to Plasmodium falciparum in the mosquito Anopheles stephensi

Medical and veterinary entomology, 1998-07, Vol.12 (3), p.302-312

1998

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Genetically Attenuated, P36p-Deficient Malarial Sporozoites Induce Protective Immunity and Apoptosis of Infected Liver Cells

Proceedings of the National Academy of Sciences - PNAS, 2005-08, Vol.102 (34), p.12194-12199

2005

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Plasmodium liver load following parenteral sporozoite administration in rodents

Vaccine, 2013-07, Vol.31 (34), p.3410-3416

2013

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Large-scale production of Plasmodium vivax sporozoites

Parasitology, 1990-12, Vol.101 Pt 3 (3), p.317-320

1990

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Plasmodium falciparum ookinetes migrate intercellularly through Anopheles stephensi midgut epithelium

Parasitology research (1987), 1989, Vol.76 (1), p.13-19

1989

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HGF/MET signalling protects Plasmodium‐infected host cells from apoptosis

Cellular microbiology, 2005-04, Vol.7 (4), p.603-609

2005

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Transmission blockade of Plasmodium falciparum: its variability with gametocyte numbers and concentration of antibody

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1987-01, Vol.81 (3), p.491-493

1987

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Could British Mosquitoes Transmit Falciparum Malaria?

Parasitology today (Regular ed.), 1998-09, Vol.14 (9), p.344-345

1998

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Clinical outcome of experimental human malaria induced by Plasmodium falciparum-infected mosquitoes

Netherlands journal of medicine, 2005-02, Vol.63 (2), p.52-58

2005

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Reduced Plasmodium berghei sporozoite liver load associates with low protective efficacy after intradermal immunization

Parasite immunology, 2012-12, Vol.34 (12), p.562

2012

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Transmission blocking antibody of the Plasmodium falciparum zygote/ookinete surface protein Pfs25 also influences sporozoite development

Parasite immunology, 1992-09, Vol.14 (5), p.471-479

1992

Volltextzugriff (PDF)

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The Spiroindolone Drug Candidate NITD609 Potently Inhibits Gametocytogenesis and Blocks Plasmodium falciparum Transmission to Anopheles Mosquito Vector

A Pfs48/45-based vaccine to block Plasmodium falciparum transmission: phase 1, open-label, clinical trial

Reduced Plasmodium berghei sporozoite liver load associates with low protective efficacy after intradermal immunization

Inhibition of Plasmodium falciparum Oocyst Production by Membrane-Permeant Cysteine Protease Inhibitor E64d

A Central Role for P48/45 in Malaria Parasite Male Gamete Fertility

A combination of new screening assays for prioritization of transmission-blocking antimalarials reveals distinct dynamics of marketed and experimental drugs

Leukocytes in a Plasmodium falciparum-infected blood meal reduce transmission of malaria to Anopheles mosquitoes

Precise Timing of Expression of a Plasmodium falciparum- derived Transgene in Plasmodium berghei Is a Critical Determinant of Subsequent Subcellular Localization

A Role for Apical Membrane Antigen 1 during Invasion of Hepatocytes by Plasmodium falciparum Sporozoites

Plasmodium falciparum:Infectivity of Cultured, Synchronized Gametocytes to Mosquitoes

Functional Equivalence of Structurally Distinct Ribosomes in the Malaria Parasite, Plasmodium berghei

Feeding behaviour and sporozoite ejection by infected Anopheles stephensi

Infectivity of cultured Plasmodium falciparum gametocytes to mosquitoes

High efficiency transfection of Plasmodium berghei facilitates novel selection procedures

Genetics of refractoriness to Plasmodium falciparum in the mosquito Anopheles stephensi

Genetically Attenuated, P36p-Deficient Malarial Sporozoites Induce Protective Immunity and Apoptosis of Infected Liver Cells

Plasmodium liver load following parenteral sporozoite administration in rodents

Large-scale production of Plasmodium vivax sporozoites

Plasmodium falciparum ookinetes migrate intercellularly through Anopheles stephensi midgut epithelium

HGF/MET signalling protects Plasmodium‐infected host cells from apoptosis

Transmission blockade of Plasmodium falciparum: its variability with gametocyte numbers and concentration of antibody

Could British Mosquitoes Transmit Falciparum Malaria?

Clinical outcome of experimental human malaria induced by Plasmodium falciparum-infected mosquitoes

Reduced Plasmodium berghei sporozoite liver load associates with low protective efficacy after intradermal immunization

Transmission blocking antibody of the Plasmodium falciparum zygote/ookinete surface protein Pfs25 also influences sporozoite development

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