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HIV, transmitted drug resistance, and the paradox of preexposure prophylaxis

Proceedings of the National Academy of Sciences - PNAS, 2010-07, Vol.107 (27), p.12381-12386

2010

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Genital Immune Cell Activation and Tenofovir Gel Efficacy: A Case-Control Study

Clinical infectious diseases, 2022-09, Vol.75 (6), p.1088-1091

2022

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Complete Protection from Repeated Vaginal Simian-Human Immunodeficiency Virus Exposures in Macaques by a Topical Gel Containing Tenofovir Alone or with Emtricitabine

Journal of Virology, 2009-10, Vol.83 (20), p.10358-10365

2009

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Editorial: Pharmacokinetics and Pharmacodynamics of Pre-Exposure Prophylaxis Against HIV

Frontiers in pharmacology, 2020-08, Vol.11, p.1288-1288

2020

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Prophylactic Efficacy of Oral Emtricitabine and Tenofovir Disoproxil Fumarate Combination Therapy Against a Tenofovir-Resistant Simian/Human Immunodeficiency Virus Containing the K65R Mutation in Macaques

The Journal of infectious diseases, 2013-08, Vol.208 (3), p.463-467

2013

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Depot-medroxyprogesterone acetate does not reduce the prophylactic efficacy of emtricitabine and tenofovir disoproxil fumarate in macaques

Journal of acquired immune deficiency syndromes (1999), 2014-12, Vol.67 (4), p.365

2014

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The long-acting integrase inhibitor GSK744 protects macaques from repeated intravaginal SHIV challenge

Science translational medicine, 2015-01, Vol.7 (270), p.270ra5

2015

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The predictive value of macaque models of preexposure prophylaxis for HIV prevention

Current opinion in HIV & AIDS, 2022-07, Vol.17 (4), p.179

2022

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The Epidemiology of Antiretroviral Drug Resistance among Drug-Naive HIV-1-Infected Persons in 10 US Cities

The Journal of infectious diseases, 2004-06, Vol.189 (12), p.2174-2181

2004

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Pharmacokinetics of vaginally applied integrase inhibitors in macaques

Journal of antimicrobial chemotherapy, 2021-10, Vol.76 (11), p.2894-2901

2021

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On the Death Rate of Abortively Infected Cells: Estimation from Simian-Human Immunodeficiency Virus Infection

Journal of virology, 2017-09, Vol.91 (18)

2017

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The effect of depot medroxyprogesterone acetate on tenofovir alafenamide in rhesus macaques

Antiviral research, 2021-02, Vol.186, p.105001-105001, Article 105001

2021

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Nondaily preexposure prophylaxis for HIV prevention

Current opinion in HIV & AIDS, 2016-01, Vol.11 (1), p.94

2016

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Oral pre-exposure prophylaxis for HIV prevention

Trends in pharmacological sciences (Regular ed.), 2010-02, Vol.31 (2), p.74-81

2010

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Animal models of antiretroviral prophylaxis for HIV prevention

Current opinion in HIV & AIDS, 2012-11, Vol.7 (6), p.505

2012

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Protection Against Rectal Chimeric Simian/Human Immunodeficiency Virus Transmission in Macaques by Rectal-Specific Gel Formulations of Maraviroc and Tenofovir

The Journal of infectious diseases, 2015-12, Vol.212 (12), p.1988-1995

2015

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Prevention of rectal SHIV transmission in macaques by daily or intermittent prophylaxis with emtricitabine and tenofovir

PLoS medicine, 2008-02, Vol.5 (2), p.291-299

2008

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Postexposure protection of macaques from vaginal SHIV infection by topical integrase inhibitors

Science translational medicine, 2014-03, Vol.6 (227), p.227ra35

2014

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SHIV susceptibility changes during the menstrual cycle of pigtail macaques

Journal of medical primatology, 2014-10, Vol.43 (5), p.310-316

2014

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Ultra-long-acting removable drug delivery system for HIV treatment and prevention

Nature communications, 2018-10, Vol.9 (1), p.4156-11, Article 4156

2018

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HIV-1 drug resistance genotyping from dried blood spots stored for 1 year at 4 degrees C

Journal of antimicrobial chemotherapy, 2008-06, Vol.61 (6), p.1217-1220

2008

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Drug resistance emergence in macaques administered cabotegravir long-acting for pre-exposure prophylaxis during acute SHIV infection

Nature communications, 2019-05, Vol.10 (1), p.2005-2005, Article 2005

2019

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Physiologic doses of depot-medroxyprogesterone acetate do not increase acute plasma simian HIV viremia or mucosal virus shedding in pigtail macaques

AIDS (London), 2014-06, Vol.28 (10), p.1431-1439

2014

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Durable Protection from Vaginal Simian-Human Immunodeficiency Virus Infection in Macaques by Tenofovir Gel and Its Relationship to Drug Levels in Tissue

Journal of Virology, 2012-01, Vol.86 (2), p.718-725

2012

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The Fitness Cost of Mutations Associated with Human Immunodeficiency Virus Type 1 Drug Resistance Is Modulated by Mutational Interactions

Journal of Virology, 2007-03, Vol.81 (6), p.3037-3041

2007

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HIV, transmitted drug resistance, and the paradox of preexposure prophylaxis

Genital Immune Cell Activation and Tenofovir Gel Efficacy: A Case-Control Study

Complete Protection from Repeated Vaginal Simian-Human Immunodeficiency Virus Exposures in Macaques by a Topical Gel Containing Tenofovir Alone or with Emtricitabine

Editorial: Pharmacokinetics and Pharmacodynamics of Pre-Exposure Prophylaxis Against HIV

Prophylactic Efficacy of Oral Emtricitabine and Tenofovir Disoproxil Fumarate Combination Therapy Against a Tenofovir-Resistant Simian/Human Immunodeficiency Virus Containing the K65R Mutation in Macaques

Depot-medroxyprogesterone acetate does not reduce the prophylactic efficacy of emtricitabine and tenofovir disoproxil fumarate in macaques

The long-acting integrase inhibitor GSK744 protects macaques from repeated intravaginal SHIV challenge

The predictive value of macaque models of preexposure prophylaxis for HIV prevention

The Epidemiology of Antiretroviral Drug Resistance among Drug-Naive HIV-1-Infected Persons in 10 US Cities

Pharmacokinetics of vaginally applied integrase inhibitors in macaques

On the Death Rate of Abortively Infected Cells: Estimation from Simian-Human Immunodeficiency Virus Infection

The effect of depot medroxyprogesterone acetate on tenofovir alafenamide in rhesus macaques

Nondaily preexposure prophylaxis for HIV prevention

Oral pre-exposure prophylaxis for HIV prevention

Animal models of antiretroviral prophylaxis for HIV prevention

Protection Against Rectal Chimeric Simian/Human Immunodeficiency Virus Transmission in Macaques by Rectal-Specific Gel Formulations of Maraviroc and Tenofovir

Prevention of rectal SHIV transmission in macaques by daily or intermittent prophylaxis with emtricitabine and tenofovir

Postexposure protection of macaques from vaginal SHIV infection by topical integrase inhibitors

SHIV susceptibility changes during the menstrual cycle of pigtail macaques

Ultra-long-acting removable drug delivery system for HIV treatment and prevention

HIV-1 drug resistance genotyping from dried blood spots stored for 1 year at 4 degrees C

Drug resistance emergence in macaques administered cabotegravir long-acting for pre-exposure prophylaxis during acute SHIV infection

Physiologic doses of depot-medroxyprogesterone acetate do not increase acute plasma simian HIV viremia or mucosal virus shedding in pigtail macaques

Durable Protection from Vaginal Simian-Human Immunodeficiency Virus Infection in Macaques by Tenofovir Gel and Its Relationship to Drug Levels in Tissue

The Fitness Cost of Mutations Associated with Human Immunodeficiency Virus Type 1 Drug Resistance Is Modulated by Mutational Interactions

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