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Adenosine A2A receptor antagonists: from caffeine to selective non‐xanthines

British journal of pharmacology, 2022-07, Vol.179 (14), p.3496-3511

2022

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Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development

Frontiers in cellular neuroscience, 2019-03, Vol.13, p.124-124

2019

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A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy

Medicinal research reviews, 2018-07, Vol.38 (4), p.1031-1072

2018

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A2B Adenosine Receptor and Cancer

International journal of molecular sciences, 2019-10, Vol.20 (20), p.5139

2019

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Structure of an Agonist-Bound Human A2A Adenosine Receptor

Science (American Association for the Advancement of Science), 2011-04, Vol.332 (6027), p.322-327

2011

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Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling

Structure (London), 2018-02, Vol.26 (2), p.259-269.e5

2018

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Two disparate ligand-binding sites in the human P2Y1 receptor

Nature (London), 2015-04, Vol.520 (7547), p.317-321

2015

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Allosteric Coupling of Drug Binding and Intracellular Signaling in the A2A Adenosine Receptor

Cell, 2018-01, Vol.172 (1-2), p.68-80.e12

2018

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Fragment-based design of selective GPCR ligands guided by free energy simulations

Chemical communications (Cambridge, England), 2021-11, Vol.57 (92), p.1235-1238

2021

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Adenosine receptors as therapeutic targets

Nature reviews. Drug discovery, 2006-03, Vol.5 (3), p.247-264

2006

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On the G protein-coupling selectivity of the native A2B adenosine receptor

Biochemical pharmacology, 2018-05, Vol.151 (C), p.201-213

2018

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Agonist-bound structure of the human P2Y12 receptor

Nature (London), 2014-05, Vol.509 (7498), p.119-122

2014

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Purinergic Signaling in Mast Cell Degranulation and Asthma

Frontiers in pharmacology, 2017-12, Vol.8, p.947-947

2017

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Ligand design by targeting a binding site water

Chemical science (Cambridge), 2020-11, Vol.12 (3), p.96-968

2020

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Species dependence of A3 adenosine receptor pharmacology and function

Purinergic signalling, 2023-09, Vol.19 (3), p.523-550

2023

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Anionic phospholipids control mechanisms of GPCR-G protein recognition

Nature communications, 2023-02, Vol.14 (1), p.794-794, Article 794

2023

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Salvianolic acids from antithrombotic Traditional Chinese Medicine Danshen are antagonists of human P2Y1 and P2Y12 receptors

Scientific reports, 2018-05, Vol.8 (1), p.1-9, Article 8084

2018

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Nucleotides Acting at P2Y Receptors: Connecting Structure and Function

Molecular pharmacology, 2015-08, Vol.88 (2), p.220-230

2015

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Novel alendronate-CGS21680 conjugate reduces bone resorption and induces new bone formation in post-menopausal osteoporosis and inflammatory osteolysis mouse models

Arthritis research & therapy, 2022-12, Vol.24 (1), p.265-13, Article 265

2022

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Genetic and functional modulation by agonist MRS5698 and allosteric enhancer LUF6000 at the native A3 adenosine receptor in HL-60 cells

Purinergic signalling, 2024-10, Vol.20 (5), p.559-570

2024

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Pharmacological characterization of DPTN and other selective A3 adenosine receptor antagonists

Purinergic signalling, 2021-12, Vol.17 (4), p.737-746

2021

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Probing biased/partial agonism at the G protein-coupled A2B adenosine receptor

Biochemical pharmacology, 2014-08, Vol.90 (3), p.297-306

2014

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Progress in the pursuit of therapeutic adenosine receptor antagonists

Medicinal research reviews, 2006-03, Vol.26 (2), p.131-159

2006

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Fluorescent A2A and A3 adenosine receptor antagonists as flow cytometry probes

Purinergic signalling, 2023-09, Vol.19 (3), p.565-578

2023

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Limits of Ligand Selectivity from Docking to Models: In Silico Screening for A1 Adenosine Receptor Antagonists

PloS one, 2012-11, Vol.7 (11), p.e49910

2012

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Adenosine A2A receptor antagonists: from caffeine to selective non‐xanthines

Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development

A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy

A2B Adenosine Receptor and Cancer

Structure of an Agonist-Bound Human A2A Adenosine Receptor

Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling

Two disparate ligand-binding sites in the human P2Y1 receptor

Allosteric Coupling of Drug Binding and Intracellular Signaling in the A2A Adenosine Receptor

Fragment-based design of selective GPCR ligands guided by free energy simulations

Adenosine receptors as therapeutic targets

On the G protein-coupling selectivity of the native A2B adenosine receptor

Agonist-bound structure of the human P2Y12 receptor

Purinergic Signaling in Mast Cell Degranulation and Asthma

Ligand design by targeting a binding site water

Species dependence of A3 adenosine receptor pharmacology and function

Anionic phospholipids control mechanisms of GPCR-G protein recognition

Salvianolic acids from antithrombotic Traditional Chinese Medicine Danshen are antagonists of human P2Y1 and P2Y12 receptors

Nucleotides Acting at P2Y Receptors: Connecting Structure and Function

Novel alendronate-CGS21680 conjugate reduces bone resorption and induces new bone formation in post-menopausal osteoporosis and inflammatory osteolysis mouse models

Genetic and functional modulation by agonist MRS5698 and allosteric enhancer LUF6000 at the native A3 adenosine receptor in HL-60 cells

Pharmacological characterization of DPTN and other selective A3 adenosine receptor antagonists

Probing biased/partial agonism at the G protein-coupled A2B adenosine receptor

Progress in the pursuit of therapeutic adenosine receptor antagonists

Fluorescent A2A and A3 adenosine receptor antagonists as flow cytometry probes

Limits of Ligand Selectivity from Docking to Models: In Silico Screening for A1 Adenosine Receptor Antagonists

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