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Interferon-induced Ifit proteins: their role in viral pathogenesis

Journal of virology, 2015-03, Vol.89 (5), p.2462-2468

2015

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Ifit2 deficiency restricts microglial activation and leukocyte migration following murine coronavirus (m-CoV) CNS infection

PLoS pathogens, 2020-11, Vol.16 (11), p.e1009034-e1009034

2020

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Ubiquitination of the Transcription Factor IRF-3 Activates RIPA, the Apoptotic Pathway that Protects Mice from Viral Pathogenesis

Immunity (Cambridge, Mass.), 2016-05, Vol.44 (5), p.1151-1161

2016

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Herpes simplex virus 1 evades cellular antiviral response by inducing microRNA-24, which attenuates STING synthesis

PLoS pathogens, 2021-09, Vol.17 (9), p.e1009950-e1009950

2021

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Tyrosine phosphorylation in Toll-like receptor signaling

Cytokine & growth factor reviews, 2014-10, Vol.25 (5), p.533-541

2014

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Cell-type-specific need of Ddx3 and PACT for interferon induction by RNA viruses

Journal of virology, 2023-12, Vol.97 (12), p.e0130423-e0130423

2023

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dsRNA-activation of TLR3 and RLR signaling: gene induction-dependent and independent effects

Journal of interferon & cytokine research, 2014-06, Vol.34 (6), p.427-436

2014

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The antiviral action of the RIG-I induced pathway of apoptosis (RIPA) is enhanced by its ability to degrade Otulin, which deubiquitinates IRF3

Cell death and differentiation, 2022-03, Vol.29 (3), p.504-513

2022

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Interferons and viral infections

BioFactors (Oxford), 2009-01, Vol.35 (1), p.14-20

2009

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Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis

Nature communications, 2020-02, Vol.11 (1), p.900-15, Article 900

2020

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Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis

PLoS pathogens, 2012-05, Vol.8 (5), p.e1002712-e1002712

2012

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Interferons at age 50: past, current and future impact on biomedicine

Nature reviews. Drug discovery, 2007-12, Vol.6 (12), p.975-990

2007

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RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway

Protein & Cell, 2017-03, Vol.8 (3), p.165-168

2017

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A new mechanism of interferon's antiviral action: Induction of autophagy, essential for paramyxovirus replication, is inhibited by the interferon stimulated gene, TDRD7

PLoS pathogens, 2018-01, Vol.14 (1), p.e1006877

2018

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Biphasic and cardiomyocyte-specific IFIT activity protects cardiomyocytes from enteroviral infection

PLoS pathogens, 2019-04, Vol.15 (4), p.e1007674-e1007674

2019

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p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (1), p.E89-E98

2013

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No Love Lost Between Viruses and Interferons

Annual review of virology, 2015-11, Vol.2 (1), p.549-572

2015

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The ISG56/IFIT1 gene family

Journal of interferon & cytokine research, 2011-01, Vol.31 (1), p.71-78

2011

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2′- O methylation of the viral mRNA cap evades host restriction by IFIT family members

Nature (London), 2010-11, Vol.468 (7322), p.452-456

2010

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Interferon induction by STING requires its translocation to the late endosomes

Traffic (Copenhagen, Denmark), 2023-12, Vol.24 (12), p.576-586

2023

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IRF3-mediated pathogenicity in a murine model of human hepatitis A

PLoS pathogens, 2021-09, Vol.17 (9), p.e1009960-e1009960

2021

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STING Requires the Adaptor TRIF to Trigger Innate Immune Responses to Microbial Infection

Cell host & microbe, 2016-09, Vol.20 (3), p.329-341

2016

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2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo

PLoS pathogens, 2012, Vol.8 (5), p.e1002698-e1002698

2012

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Attenuation of cGAS‐STING signaling is mediated by a p62/SQSTM1‐dependent autophagy pathway activated by TBK1

The EMBO journal, 2018-04, Vol.37 (8), p.n/a

2018

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Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1

The EMBO journal, 2008-12, Vol.27 (24), p.3311-3321

2008

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Interferon-induced Ifit proteins: their role in viral pathogenesis

Ifit2 deficiency restricts microglial activation and leukocyte migration following murine coronavirus (m-CoV) CNS infection

Ubiquitination of the Transcription Factor IRF-3 Activates RIPA, the Apoptotic Pathway that Protects Mice from Viral Pathogenesis

Herpes simplex virus 1 evades cellular antiviral response by inducing microRNA-24, which attenuates STING synthesis

Tyrosine phosphorylation in Toll-like receptor signaling

Cell-type-specific need of Ddx3 and PACT for interferon induction by RNA viruses

dsRNA-activation of TLR3 and RLR signaling: gene induction-dependent and independent effects

The antiviral action of the RIG-I induced pathway of apoptosis (RIPA) is enhanced by its ability to degrade Otulin, which deubiquitinates IRF3

Interferons and viral infections

Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis

Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis

Interferons at age 50: past, current and future impact on biomedicine

RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway

A new mechanism of interferon's antiviral action: Induction of autophagy, essential for paramyxovirus replication, is inhibited by the interferon stimulated gene, TDRD7

Biphasic and cardiomyocyte-specific IFIT activity protects cardiomyocytes from enteroviral infection

p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs

No Love Lost Between Viruses and Interferons

The ISG56/IFIT1 gene family

2′- O methylation of the viral mRNA cap evades host restriction by IFIT family members

Interferon induction by STING requires its translocation to the late endosomes

IRF3-mediated pathogenicity in a murine model of human hepatitis A

STING Requires the Adaptor TRIF to Trigger Innate Immune Responses to Microbial Infection

2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo

Attenuation of cGAS‐STING signaling is mediated by a p62/SQSTM1‐dependent autophagy pathway activated by TBK1

Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1

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