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Systematic review and comparison of national and international guidelines on diverticular disease

International journal of colorectal disease, 2018-03, Vol.33 (3), p.261-272

2018

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Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver

Clinical pharmacology and therapeutics, 2013-07, Vol.94 (1), p.126-141

2013

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ITC Recommendations for Transporter Kinetic Parameter Estimation and Translational Modeling of Transport-Mediated PK and DDIs in Humans

Clinical pharmacology and therapeutics, 2013-07, Vol.94 (1), p.64-79

2013

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Identification of the Effect of Multiple Polymorphisms on the Pharmacokinetics of Simvastatin and Simvastatin Acid Using a Population-Modeling Approach

Clinical pharmacology and therapeutics, 2014-07, Vol.96 (1), p.90-100

2014

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ITC Commentary on the Prediction of Digoxin Clinical Drug-Drug Interactions from In Vitro Transporter Assays

Clinical pharmacology and therapeutics, 2014-09, Vol.96 (3), p.298-301

2014

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Evaluation of Various Static In Vitro-In Vivo Extrapolation Models for Risk Assessment of the CYP3A Inhibition Potential of an Investigational Drug

Clinical pharmacology and therapeutics, 2014-02, Vol.95 (2), p.189-198

2014

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CYP3A4 substrate selection and substitution in the prediction of potential drug-drug interactions

The Journal of pharmacology and experimental therapeutics, 2005-07, Vol.314 (1), p.180-190

2005

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Isoform selectivity and kinetics of morphine 3- and 6-glucuronidation by human udp-glucuronosyltransferases: evidence for atypical glucuronidation kinetics by UGT2B7

Drug metabolism and disposition, 2003-09, Vol.31 (9), p.1086-1089

2003

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Prediction of metabolic clearance using fresh human hepatocytes: Comparison with cryopreserved hepatocytes and hepatic microsomes for five benzodiazepines

Xenobiotica, 2008-04, Vol.38 (4), p.353-367

2008

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Methods for predicting in vivo pharmacokinetics using data from in vitro assays

Current drug metabolism, 2008-11, Vol.9 (9), p.940-951

2008

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Intestinal and hepatic metabolic activity of five cytochrome P450 enzymes: impact on prediction of first-pass metabolism

The Journal of pharmacology and experimental therapeutics, 2006-09, Vol.318 (3), p.1220-1229

2006

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Microsomal prediction of in vivo clearance and associated interindividual variability of six benzodiazepines in humans

Xenobiotica, 2005-06, Vol.35 (6), p.603-625

2005

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Prediction of time-dependent CYP3A4 drug-drug interactions: impact of enzyme degradation, parallel elimination pathways, and intestinal inhibition

Drug metabolism and disposition, 2006-01, Vol.34 (1), p.166

2006

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Human udp-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid

Drug metabolism and disposition, 2004-04, Vol.32 (4), p.413

2004

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Prediction of in vivo drug–drug interactions from in vitro data: impact of incorporating parallel pathways of drug elimination and inhibitor absorption rate constant

British journal of clinical pharmacology, 2005-11, Vol.60 (5), p.508-518

2005

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Utility of recombinant enzyme kinetics in prediction of human clearance: impact of variability, CYP3A5, and CYP2C19 on CYP3A4 probe substrates

Drug metabolism and disposition, 2004-12, Vol.32 (12), p.1411-1420

2004

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Modelling atypical CYP3A4 kinetics: principles and pragmatism

Archives of biochemistry and biophysics, 2005-01, Vol.433 (2), p.351-360

2005

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Multisite kinetic analysis of interactions between prototypical CYP3A4 subgroup substrates: midazolam, testosterone, and nifedipine

Drug metabolism and disposition, 2003-09, Vol.31 (9), p.1108

2003

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Quinidine and haloperidol as modifiers of CYP3A4 activity: multisite kinetic model approach

Drug metabolism and disposition, 2002-12, Vol.30 (12), p.1512-1522

2002

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Progress Towards Prediction of Human Pharmacokinetic Parameters from In Vitro Technologies

Drug metabolism reviews, 2003-01, Vol.35 (4), p.393-415

2003

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Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver : Transporters in Drug Development and Clinical Pharmacology

Clinical pharmacology and therapeutics, 2013, Vol.94 (1), p.126-141

2013

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ITC Recommendations for Transporter Kinetic Parameter Estimation and Translational Modeling of Transport-Mediated PK and DDIs in Humans : Transporters in Drug Development and Clinical Pharmacology

Clinical pharmacology and therapeutics, 2013, Vol.94 (1), p.64-79

2013

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Comparative pharmacokinetics and bioavailability of two cotrimoxazole preparations

Pharmazie, 1998-07, Vol.53 (7), p.470-472

1998

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The influence of diluents on the physical characteristics of paracetamol tablets

Pharmazie, 1993-11, Vol.48 (11), p.865-866

1993

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5.35 - Modeling and Simulation of Pharmacokinetic Aspects of Cytochrome P450-Based Metabolic Drug–Drug Interactions

Comprehensive Medicinal Chemistry II, 2007, Vol.5, p.827-846

Second Edition, 2007

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Systematic review and comparison of national and international guidelines on diverticular disease

Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver

ITC Recommendations for Transporter Kinetic Parameter Estimation and Translational Modeling of Transport-Mediated PK and DDIs in Humans

Identification of the Effect of Multiple Polymorphisms on the Pharmacokinetics of Simvastatin and Simvastatin Acid Using a Population-Modeling Approach

ITC Commentary on the Prediction of Digoxin Clinical Drug-Drug Interactions from In Vitro Transporter Assays

Evaluation of Various Static In Vitro-In Vivo Extrapolation Models for Risk Assessment of the CYP3A Inhibition Potential of an Investigational Drug

CYP3A4 substrate selection and substitution in the prediction of potential drug-drug interactions

Isoform selectivity and kinetics of morphine 3- and 6-glucuronidation by human udp-glucuronosyltransferases: evidence for atypical glucuronidation kinetics by UGT2B7

Prediction of metabolic clearance using fresh human hepatocytes: Comparison with cryopreserved hepatocytes and hepatic microsomes for five benzodiazepines

Methods for predicting in vivo pharmacokinetics using data from in vitro assays

Intestinal and hepatic metabolic activity of five cytochrome P450 enzymes: impact on prediction of first-pass metabolism

Microsomal prediction of in vivo clearance and associated interindividual variability of six benzodiazepines in humans

Prediction of time-dependent CYP3A4 drug-drug interactions: impact of enzyme degradation, parallel elimination pathways, and intestinal inhibition

Human udp-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid

Prediction of in vivo drug–drug interactions from in vitro data: impact of incorporating parallel pathways of drug elimination and inhibitor absorption rate constant

Utility of recombinant enzyme kinetics in prediction of human clearance: impact of variability, CYP3A5, and CYP2C19 on CYP3A4 probe substrates

Modelling atypical CYP3A4 kinetics: principles and pragmatism

Multisite kinetic analysis of interactions between prototypical CYP3A4 subgroup substrates: midazolam, testosterone, and nifedipine

Quinidine and haloperidol as modifiers of CYP3A4 activity: multisite kinetic model approach

Progress Towards Prediction of Human Pharmacokinetic Parameters from In Vitro Technologies

Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver : Transporters in Drug Development and Clinical Pharmacology

ITC Recommendations for Transporter Kinetic Parameter Estimation and Translational Modeling of Transport-Mediated PK and DDIs in Humans : Transporters in Drug Development and Clinical Pharmacology

Comparative pharmacokinetics and bioavailability of two cotrimoxazole preparations

The influence of diluents on the physical characteristics of paracetamol tablets

5.35 - Modeling and Simulation of Pharmacokinetic Aspects of Cytochrome P450-Based Metabolic Drug–Drug Interactions

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