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Structures and Synthesis of Hitoyopodins: Bioactive Aromatic Sesquiterpenoids Produced by the Mushroom Coprinopsis cinerea

Organic letters, 2018-10, Vol.20 (19), p.6294-6297

2018

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Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival

Scientific reports, 2016-05, Vol.6 (1), p.26521-26521, Article 26521

2016

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6,9-Dihydroxytetrangulol, a novel angucyclinone antibiotic accumulated in kiqO gene disruptant in the biosynthesis of kinanthraquinone

Journal of antibiotics, 2021-09, Vol.74 (9), p.593-595

2021

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Biosynthetic gene cluster identification and biological activity of lucilactaene from Fusarium sp. RK97-94

Bioscience, biotechnology, and biochemistry, 2020-06, Vol.84 (6), p.1303-1307

2020

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Target identification of small molecules based on chemical biology approaches

Molecular bioSystems, 2013-05, Vol.9 (5), p.897-914

2013

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Nocardamin glucuronide, a new member of the ferrioxamine siderophores isolated from the ascamycin-producing strain Streptomyces sp. 80H647

Journal of antibiotics, 2019-12, Vol.72 (12), p.991-995

2019

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Zealpeptaibolin, an 11-mer cytotoxic peptaibol group with 3 Aib-Pro motifs isolated from Trichoderma sp. RK10-F026

Journal of antibiotics, 2021-08, Vol.74 (8), p.485-495

2021

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Glyoxalase I disruption and external carbonyl stress impair mitochondrial function in human induced pluripotent stem cells and derived neurons

Translational psychiatry, 2021-05, Vol.11 (1), p.275-275, Article 275

2021

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Productivity and bioactivity of enokipodins A-D of Flammulina rossica and Flammulina velutipes

Bioscience, biotechnology, and biochemistry, 2020-05, Vol.84 (5), p.876-886

2020

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An overproduction of astellolides induced by genetic disruption of chromatin-remodeling factors in Aspergillus oryzae

Journal of antibiotics, 2016-01, Vol.69 (1), p.4-8

2016

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Stereocomplementary Chemoenzymatic Pictet–Spengler Reactions for Formation of Rare Azepino-indole Frameworks: Discovery of Antimalarial Compounds

ACS catalysis, 2019-08, Vol.9 (8), p.7443-7448

2019

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Integrated profiling methods for identifying the targets of bioactive compounds: MorphoBase and ChemProteoBase

Natural product reports, 2016-05, Vol.33 (5), p.621-625

2016

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Opantimycin A, a new metabolite isolated from Streptomyces sp. RK88-1355

Journal of antibiotics, 2017-02, Vol.70 (2), p.222-225

2017

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cis-Decalin-containing tetramic acids as inhibitors of insect steroidogenic glutathione S-transferase Noppera-bo

PloS one, 2023-08, Vol.18 (8), p.e0290851-e0290851

2023

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N-Acetyl-α-hydroxy-β-oxotryptamine, a racemic natural product isolated from Streptomyces sp. 80H647

Journal of antibiotics, 2021-07, Vol.74 (7), p.477-479

2021

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Privileged Biorenewable Secologanin‐Based Diversity‐Oriented Synthesis for Pseudo‐Natural Alkaloids: Uncovering Novel Neuroprotective and Antimalarial Frameworks

ChemSusChem, 2021-12, Vol.14 (23), p.5320-5327

2021

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High-throughput screening identifies artesunate as selective inhibitor of cancer stemness: Involvement of mitochondrial metabolism

Biochemical and biophysical research communications, 2016-09, Vol.477 (4), p.737-742

2016

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Phenotypic screening meets natural products in drug discovery

Bioscience, biotechnology, and biochemistry, 2017-01, Vol.81 (1), p.28-31

2017

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Wakodecaline C, new tetrahydrofuran-fused decalin metabolite isolated from fungus Pyrenochaetopsis sp. RK10-F058

Journal of antibiotics, 2023-06, Vol.76 (6), p.346-350

2023

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Structure and biological activity of Metarhizin C, a stereoisomer of BR-050 from Tolypocladium album RK17-F0007

Journal of antibiotics, 2019-12, Vol.72 (12), p.996-1000

2019

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Trachyspic acid 19-butyl ester, a new inhibitor of Plk1 polo box domain-dependent recognition from uncharacterized fungus RKGS-F2684

Journal of antibiotics, 2017-05, Vol.70 (5), p.705-707

2017

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Vacuolar H+‐ATPase inhibitors overcome Bcl‐xL‐mediated chemoresistance through restoration of a caspase‐independent apoptotic pathway

Cancer science, 2009-08, Vol.100 (8), p.1460-1467

2009

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Discovery of small-molecule modulator of heterotrimeric Gi-protein by integrated phenotypic profiling and chemical proteomics

Bioscience, biotechnology, and biochemistry, 2020-12, Vol.84 (12), p.2484-2490

2020

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Methyl 3‑((6-Methoxy-1,4-dihydroindeno[1,2‑c]pyrazol-3-yl)amino)benzoate (GN39482) as a Tubulin Polymerization Inhibitor Identified by MorphoBase and ChemProteoBase Profiling Methods

Journal of medicinal chemistry, 2015-05, Vol.58 (10), p.4230-4241

2015

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Isolation of new lucilactaene derivatives from P450 monooxygenase and aldehyde dehydrogenase knockout Fusarium sp. RK97-94 strains and their biological activities

Journal of antibiotics, 2022-07, Vol.75 (7), p.361-374

2022

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Structures and Synthesis of Hitoyopodins: Bioactive Aromatic Sesquiterpenoids Produced by the Mushroom Coprinopsis cinerea

Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival

6,9-Dihydroxytetrangulol, a novel angucyclinone antibiotic accumulated in kiqO gene disruptant in the biosynthesis of kinanthraquinone

Biosynthetic gene cluster identification and biological activity of lucilactaene from Fusarium sp. RK97-94

Target identification of small molecules based on chemical biology approaches

Nocardamin glucuronide, a new member of the ferrioxamine siderophores isolated from the ascamycin-producing strain Streptomyces sp. 80H647

Zealpeptaibolin, an 11-mer cytotoxic peptaibol group with 3 Aib-Pro motifs isolated from Trichoderma sp. RK10-F026

Glyoxalase I disruption and external carbonyl stress impair mitochondrial function in human induced pluripotent stem cells and derived neurons

Productivity and bioactivity of enokipodins A-D of Flammulina rossica and Flammulina velutipes

An overproduction of astellolides induced by genetic disruption of chromatin-remodeling factors in Aspergillus oryzae

Stereocomplementary Chemoenzymatic Pictet–Spengler Reactions for Formation of Rare Azepino-indole Frameworks: Discovery of Antimalarial Compounds

Integrated profiling methods for identifying the targets of bioactive compounds: MorphoBase and ChemProteoBase

Opantimycin A, a new metabolite isolated from Streptomyces sp. RK88-1355

cis-Decalin-containing tetramic acids as inhibitors of insect steroidogenic glutathione S-transferase Noppera-bo

N-Acetyl-α-hydroxy-β-oxotryptamine, a racemic natural product isolated from Streptomyces sp. 80H647

Privileged Biorenewable Secologanin‐Based Diversity‐Oriented Synthesis for Pseudo‐Natural Alkaloids: Uncovering Novel Neuroprotective and Antimalarial Frameworks

High-throughput screening identifies artesunate as selective inhibitor of cancer stemness: Involvement of mitochondrial metabolism

Phenotypic screening meets natural products in drug discovery

Wakodecaline C, new tetrahydrofuran-fused decalin metabolite isolated from fungus Pyrenochaetopsis sp. RK10-F058

Structure and biological activity of Metarhizin C, a stereoisomer of BR-050 from Tolypocladium album RK17-F0007

Trachyspic acid 19-butyl ester, a new inhibitor of Plk1 polo box domain-dependent recognition from uncharacterized fungus RKGS-F2684

Vacuolar H+‐ATPase inhibitors overcome Bcl‐xL‐mediated chemoresistance through restoration of a caspase‐independent apoptotic pathway

Discovery of small-molecule modulator of heterotrimeric Gi-protein by integrated phenotypic profiling and chemical proteomics

Methyl 3‑((6-Methoxy-1,4-dihydroindeno[1,2‑c]pyrazol-3-yl)amino)benzoate (GN39482) as a Tubulin Polymerization Inhibitor Identified by MorphoBase and ChemProteoBase Profiling Methods

Isolation of new lucilactaene derivatives from P450 monooxygenase and aldehyde dehydrogenase knockout Fusarium sp. RK97-94 strains and their biological activities

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