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First in man study of EP217609, a new long-acting, neutralisable parenteral antithrombotic with a dual mechanism of action

European journal of clinical pharmacology, 2016-09, Vol.72 (9), p.1041-1050

2016

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Neutralization of EP217609, a new dual-action FIIa/FXa anticoagulant, by its specific antidote avidin: a phase I study

European journal of clinical pharmacology, 2017, Vol.73 (1), p.15-28

2017

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Pharmacokinetics and safety of roledumab, a novel human recombinant monoclonal anti-RhD antibody with an optimized Fc for improved engagement of FC[gamma]RIII, in healthy volunteers

Vox sanguinis, 2012-10, Vol.103 (3), p.213

2012

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EP42675, a synthetic parenteral dual‐action anticoagulant: pharmacokinetics, pharmacodynamics, and absence of interactions with antiplatelet drugs

Journal of thrombosis and haemostasis, 2014-01, Vol.12 (1), p.24-33

2014

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Pharmacokinetics and safety of roledumab, a novel human recombinant monoclonal anti-RhD antibody with an optimized Fc for improved engagement of FCγRIII, in healthy volunteers

Vox sanguinis, 2012-10, Vol.103 (3), p.213-222

2012

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Supporting the recommended paediatric dosing regimen for rufinamide in Lennox–Gastaut syndrome using clinical trial simulation

Journal of pharmacokinetics and pharmacodynamics, 2010-02, Vol.37 (1), p.99-118

2010

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Clinical pharmacokinetics of intranasal sumatriptan

Clinical pharmacokinetics, 2002, Vol.41 (11), p.801-811

2002

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Comparative clinical pharmacokinetics of single doses of sumatriptan following subcutaneous, oral, rectal and intranasal administration

European journal of pharmaceutical sciences, 1998-04, Vol.6 (2), p.99-104

1998

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Modeling and simulation for clinical trial design involving a categorical response : A phase II case study with naratriptan

Pharmaceutical research, 2001-08, Vol.18 (8), p.1210-1219

2001

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A population pharmacokinetic-pharmacodynamic analysis of repeated measures time-to-event pharmacodynamic responses : The antiemetic effect of ondansetron

Journal of pharmacokinetics and biopharmaceutics, 1999-12, Vol.27 (6), p.625-644

1999

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Early clinical experience with subcutaneous naratriptan in the acute treatment of migraine: a dose-ranging study

European journal of neurology, 1998-09, Vol.5 (5), p.469-477

1998

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Meta-Analysis of The Exposure/Efficacy Relationship for Sumatriptan Nasal Spray

Clinical pharmacology and therapeutics, 1999-02, Vol.65 (2), p.166-166

1999

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Cns Effects of Sumatriptan and Rizatriptan in Healthy Female Volunteers

Cephalalgia, 2002-05, Vol.22 (4), p.271-281

2002

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Safety, tolerability, and pharmacokinetics of sumatriptan in healthy subjects following ascending single intranasal doses and multiple intranasal doses

Cephalalgia, 1997-06, Vol.17 (4), p.541-550

1997

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Pharmacokinetics of Naratriptan in Adolescent Subjects with a History of Migraine

Journal of clinical pharmacology, 2001-02, Vol.41 (2), p.170-175

2001

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Mixed effect modeling of sumatriptan pharmacokinetics during drug development : II. From healthy subjects to phase 2 dose ranging in patients

Journal of pharmacokinetics and biopharmaceutics, 1999-04, Vol.27 (2), p.149-171

1999

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Population pharmacokinetics (PPK) of eribulin mesylate in patients with locally advanced or metastatic breast cancer (MBC)

Journal of clinical oncology, 2009-05, Vol.27 (15_suppl), p.2524-2524

2009

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Pharmacokinetic modelling of valproic acid from routine clinical data in Egyptian epileptic patients

European journal of clinical pharmacology, 2004-01, Vol.59 (11), p.783-790

2004

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Population pharmacokinetics of nelfinavir (NFV) and its metabolite M8 when administered with ritonavir (RTV)

Clinical pharmacology and therapeutics, 2004-02, Vol.75 (2), p.P84-P84

2004

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Population pharmacokinetics of onercept in healthy subjects

Clinical pharmacokinetics, 2005-01, Vol.44 (12), p.1295-1304

2005

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Plasma and skin suction-blister-fluid pharmacokinetics and time course of the effects of oral mizolastine

European journal of clinical pharmacology, 1996, Vol.50 (4), p.327-334

1996

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Pharmacokinetics of Sumatriptan Nasal Spray in Adolescents

Journal of clinical pharmacology, 2003-07, Vol.43 (7), p.721-726

2003

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Pharmacokinetics of Sumatriptan Nasal Spray in Children

Journal of clinical pharmacology, 2004-04, Vol.44 (4), p.359-367

2004

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Effect of encapsulation on absorption of sumatriptan tablets : Data from healthy volunteers and patients during a migraine

Clinical therapeutics, 2001-02, Vol.23 (2), p.242-251

2001

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Nocturnal profile of growth hormone secretion during sleep induced by zolpidem: a double-blind study in young adults and children

Hormone research, 1991, Vol.35 (1), p.30-34

1991

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First in man study of EP217609, a new long-acting, neutralisable parenteral antithrombotic with a dual mechanism of action

Neutralization of EP217609, a new dual-action FIIa/FXa anticoagulant, by its specific antidote avidin: a phase I study

Pharmacokinetics and safety of roledumab, a novel human recombinant monoclonal anti-RhD antibody with an optimized Fc for improved engagement of FC[gamma]RIII, in healthy volunteers

EP42675, a synthetic parenteral dual‐action anticoagulant: pharmacokinetics, pharmacodynamics, and absence of interactions with antiplatelet drugs

Pharmacokinetics and safety of roledumab, a novel human recombinant monoclonal anti-RhD antibody with an optimized Fc for improved engagement of FCγRIII, in healthy volunteers

Supporting the recommended paediatric dosing regimen for rufinamide in Lennox–Gastaut syndrome using clinical trial simulation

Clinical pharmacokinetics of intranasal sumatriptan

Comparative clinical pharmacokinetics of single doses of sumatriptan following subcutaneous, oral, rectal and intranasal administration

Modeling and simulation for clinical trial design involving a categorical response : A phase II case study with naratriptan

A population pharmacokinetic-pharmacodynamic analysis of repeated measures time-to-event pharmacodynamic responses : The antiemetic effect of ondansetron

Early clinical experience with subcutaneous naratriptan in the acute treatment of migraine: a dose-ranging study

Meta-Analysis of The Exposure/Efficacy Relationship for Sumatriptan Nasal Spray

Cns Effects of Sumatriptan and Rizatriptan in Healthy Female Volunteers

Safety, tolerability, and pharmacokinetics of sumatriptan in healthy subjects following ascending single intranasal doses and multiple intranasal doses

Pharmacokinetics of Naratriptan in Adolescent Subjects with a History of Migraine

Mixed effect modeling of sumatriptan pharmacokinetics during drug development : II. From healthy subjects to phase 2 dose ranging in patients

Population pharmacokinetics (PPK) of eribulin mesylate in patients with locally advanced or metastatic breast cancer (MBC)

Pharmacokinetic modelling of valproic acid from routine clinical data in Egyptian epileptic patients

Population pharmacokinetics of nelfinavir (NFV) and its metabolite M8 when administered with ritonavir (RTV)

Population pharmacokinetics of onercept in healthy subjects

Plasma and skin suction-blister-fluid pharmacokinetics and time course of the effects of oral mizolastine

Pharmacokinetics of Sumatriptan Nasal Spray in Adolescents

Pharmacokinetics of Sumatriptan Nasal Spray in Children

Effect of encapsulation on absorption of sumatriptan tablets : Data from healthy volunteers and patients during a migraine

Nocturnal profile of growth hormone secretion during sleep induced by zolpidem: a double-blind study in young adults and children

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