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Crystal Structure of an HSA/FcRn Complex Reveals Recycling by Competitive Mimicry of HSA Ligands at a pH-Dependent Hydrophobic Interface

Structure (London), 2013-11, Vol.21 (11), p.1966-1978

2013

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Design of a superior cytokine antagonist for topical ophthalmic use

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (10), p.3913-3918

2013

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Preclinical Development of EBI-005: An IL-1 Receptor-1 Inhibitor for the Topical Ocular Treatment of Ocular Surface Inflammatory Diseases

Eye & contact lens, 2018-05, Vol.44 (3), p.170-181

2018

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Preclinical Pharmacology and Pharmacokinetics of GW433908, a Water-Soluble Prodrug of the Human Immunodeficiency Virus Protease Inhibitor Amprenavir

Antimicrobial Agents and Chemotherapy, 2004-03, Vol.48 (3), p.791-798

2004

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IL-1 blockade for the topical treatment of ocular surface inflammatory disorders and the discovery of EBI-005, a novel IL-1 receptor inhibitor

Expert review of ophthalmology, 2014-04, Vol.9 (2), p.71-79

Furfine, Eric S

2014

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Inhibition of Wild-Type and Mutant Human Immunodeficiency Virus Type 1 Proteases by GW0385 and Other Arylsulfonamides

Biochemistry (Easton), 2004-11, Vol.43 (45), p.14500-14507

2004

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1400W Is a Slow, Tight Binding, and Highly Selective Inhibitor of Inducible Nitric-oxide Synthase in Vitro and in Vivo

The Journal of biological chemistry, 1997-02, Vol.272 (8), p.4959-4963

1997

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Metabolic complications associated with antiretroviral therapy

Antiviral Research, 2001-09, Vol.51 (3), p.151-177

2001

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Effectors of HIV-1 Protease Peptidolytic Activity

Biochemistry (Easton), 2001-09, Vol.40 (37), p.11131-11139

2001

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Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: The discovery of GW0385

Bioorganic & medicinal chemistry letters, 2006-04, Vol.16 (7), p.1788-1794

2006

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Adnectin CT-322 inhibits tumor growth and affects microvascular architecture and function in Colo205 tumor xenografts

International journal of oncology, 2011, Vol.38 (1), p.71-80

2011

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Adnectin CT-322 inhibits tumor growth and affects microvascular architecture and function in Colo205 tumor xenografts

International journal of oncology, 2011-01, Vol.38 (1), p.71

2011

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HIV protease inhibitors block adipogenesis and increase lipolysis in vitro

Antiviral research, 2000-08, Vol.47 (2), p.121-129

2000

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Stimulation of vitamin A1 acid signaling by the HIV protease inhibitor indinavir

Biochemical pharmacology, 2000-05, Vol.59 (9), p.1063-1068

2000

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Substrate Binding Is Required for Release of Product from Mammalian Protein Farnesyltransferase

The Journal of biological chemistry, 1997-04, Vol.272 (15), p.9989-9993

1997

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Protein farnesyltransferase: kinetics of farnesyl pyrophosphate binding and product release

Biochemistry (Easton), 1995-05, Vol.34 (20), p.6857-6862

1995

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N-Phenylamidines as Selective Inhibitors of Human Neuronal Nitric Oxide Synthase: Structure−Activity Studies and Demonstration of in Vivo Activity

Journal of medicinal chemistry, 1998-07, Vol.41 (15), p.2858-2871

1998

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Novel P1 chain-extended HIV protease inhibitors possessing potent anti-HIV activity and remarkable inverse antiviral resistance profiles

Bioorganic & medicinal chemistry letters, 2005-08, Vol.15 (15), p.3496-3500

2005

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Novel arylsulfonamides possessing sub-picomolar HIV protease activities and potent anti-HIV activity against wild-type and drug-resistant viral strains

Bioorganic & medicinal chemistry letters, 2004-02, Vol.14 (4), p.959-963

2004

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Synthesis and antiviral activities of novel N-alkoxy-arylsulfonamide-based HIV protease inhibitors

Bioorganic & medicinal chemistry letters, 2005-08, Vol.15 (15), p.3560-3564

2005

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Substituted N-Phenylisothioureas: Potent Inhibitors of Human Nitric Oxide Synthase with Neuronal Isoform Selectivity

Journal of medicinal chemistry, 1997-06, Vol.40 (12), p.1901-1905

1997

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Optimization of pyrrolidinone based HIV protease inhibitors

Bioorganic & medicinal chemistry letters, 2005-01, Vol.15 (1), p.81-84

2005

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HIV-1 Protease: Characterization of a Catalytically Competent Enzyme−Substrate Intermediate

Biochemistry (Easton), 2002-01, Vol.41 (4), p.1302-1307

2002

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Crystal Structure of an HSA/FcRn Complex Reveals Recycling by Competitive Mimicry of HSA Ligands at a pH-Dependent Hydrophobic Interface

Design of a superior cytokine antagonist for topical ophthalmic use

Preclinical Development of EBI-005: An IL-1 Receptor-1 Inhibitor for the Topical Ocular Treatment of Ocular Surface Inflammatory Diseases

Anti-tumor effect of CT-322 as an Adnectin inhibitor of vascular endothelial growth factor receptor-2

A fibronectin scaffold approach to bispecific inhibitors of epidermal growth factor receptor and insulin-like growth factor-I receptor

Preclinical Pharmacology and Pharmacokinetics of GW433908, a Water-Soluble Prodrug of the Human Immunodeficiency Virus Protease Inhibitor Amprenavir

IL-1 blockade for the topical treatment of ocular surface inflammatory disorders and the discovery of EBI-005, a novel IL-1 receptor inhibitor

Inhibition of Wild-Type and Mutant Human Immunodeficiency Virus Type 1 Proteases by GW0385 and Other Arylsulfonamides

1400W Is a Slow, Tight Binding, and Highly Selective Inhibitor of Inducible Nitric-oxide Synthase in Vitro and in Vivo

Metabolic complications associated with antiretroviral therapy

Effectors of HIV-1 Protease Peptidolytic Activity

Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: The discovery of GW0385

Adnectin CT-322 inhibits tumor growth and affects microvascular architecture and function in Colo205 tumor xenografts

Adnectin CT-322 inhibits tumor growth and affects microvascular architecture and function in Colo205 tumor xenografts

HIV protease inhibitors block adipogenesis and increase lipolysis in vitro

Stimulation of vitamin A1 acid signaling by the HIV protease inhibitor indinavir

Substrate Binding Is Required for Release of Product from Mammalian Protein Farnesyltransferase

Protein farnesyltransferase: kinetics of farnesyl pyrophosphate binding and product release

N-Phenylamidines as Selective Inhibitors of Human Neuronal Nitric Oxide Synthase: Structure−Activity Studies and Demonstration of in Vivo Activity

Novel P1 chain-extended HIV protease inhibitors possessing potent anti-HIV activity and remarkable inverse antiviral resistance profiles

Novel arylsulfonamides possessing sub-picomolar HIV protease activities and potent anti-HIV activity against wild-type and drug-resistant viral strains

Synthesis and antiviral activities of novel N-alkoxy-arylsulfonamide-based HIV protease inhibitors

Substituted N-Phenylisothioureas: Potent Inhibitors of Human Nitric Oxide Synthase with Neuronal Isoform Selectivity

Optimization of pyrrolidinone based HIV protease inhibitors

HIV-1 Protease: Characterization of a Catalytically Competent Enzyme−Substrate Intermediate

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