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Crystal Structure of 12-Lipoxygenase Catalytic-Domain-Inhibitor Complex Identifies a Substrate-Binding Channel for Catalysis

Structure (London), 2012-09, Vol.20 (9), p.1490-1497

2012

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Structure-based design of a thiazolidinedione which targets the mitochondrial protein mitoNEET

Bioorganic & medicinal chemistry letters, 2010-02, Vol.20 (3), p.819-823

2010

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Identification of novel monoamine oxidase B inhibitors by structure-based virtual screening

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (17), p.5295-5298

2010

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Complexes of the Outer Mitochondrial Membrane Protein MitoNEET with Resveratrol-3-Sulfate

Biochemistry (Easton), 2011-06, Vol.50 (25), p.5806-5811

2011

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Electrospray ionization mass spectrometry of soybean lipoxygenases: N-terminal acetylation, chemical modification, and solution conformation

Proteins, structure, function, and bioinformatics, 2008-02, Vol.70 (3), p.650-658

2008

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A scaffold hopping approach to identify novel monoamine oxidase B inhibitors

Bioorganic & medicinal chemistry letters, 2012-02, Vol.22 (3), p.1380-1383

2012

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EPR spectroscopy and electrospray ionization mass spectrometry reveal distinctive features of the iron site in leukocyte 12-lipoxygenase

Archives of biochemistry and biophysics, 2009-10, Vol.490 (1), p.50-56

2009

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Secondary Alkyl Hydroperoxides as Inhibitors and Alternate Substrates for Lipoxygenase

Biochemistry (Easton), 2008-01, Vol.47 (1), p.331-338

2008

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Structure–activity relationship and docking studies of thiazolidinedione-type compounds with monoamine oxidase B

Bioorganic & medicinal chemistry letters, 2011-08, Vol.21 (16), p.4798-4803

2011

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Three-Dimensional Structure of a Purple Lipoxygenase

Journal of the American Chemical Society, 2001-11, Vol.123 (44), p.10814-10820

2001

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A novel binding assay identifies high affinity ligands to the rosiglitazone binding site of mitoNEET

Bioorganic & medicinal chemistry letters, 2011-09, Vol.21 (18), p.5498-5501

2011

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Interaction between Non-Heme Iron of Lipoxygenases and Cumene Hydroperoxide: Basis for Enzyme Activation, Inactivation, and Inhibition

Journal of the American Chemical Society, 2004-02, Vol.126 (7), p.2006-2015

2004

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Structural and Thermochemical Characterization of Lipoxygenase−Catechol Complexes

Biochemistry (Easton), 1998-12, Vol.37 (51), p.17952-17957

1998

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Peroxy radical cyclization as a model for prostaglandin biosynthesis

Journal of organic chemistry, 1975-11, Vol.40 (24), p.3614-3615

1975

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Leukocyte 12‐lipoxygenase: expression, purification and physical characterization

The FASEB journal, 2008-03, Vol.22 (S1)

2008

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Position 713 Is Critical for Catalysis but Not Iron Binding in Soybean Lipoxygenase 3

Biochemistry (Easton), 1994-12, Vol.33 (50), p.15017-15022

1994

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The formation of cyclic peroxides from unsaturated hydroperoxides: models for prostaglandin biosynthesis

Journal of the American Chemical Society, 1976-09, Vol.98 (19), p.6000-6005

1976

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Structures and spectroscopic characteristics of iron(III) diethylenetriaminepentaacetic acid complexes. A non-heme iron(III) complex with relevance to the iron environment in lipoxygenases

Inorganic chemistry, 1991-10, Vol.30 (20), p.3960-3964

1991

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The lipoxygenases in developing soybean seeds, their characterization and synthesis in vitro

Plant physiology (Bethesda), 1986-12, Vol.82 (4), p.1139-1144

1986

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Role of iron in lipoxygenase catalysis

Journal of the American Chemical Society, 1990-06, Vol.112 (13), p.5375-5376

1990

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Catalysis Sensitive Conformational Changes in Soybean Lipoxygenase Revealed by Limited Proteolysis and Monoclonal Antibody Experiments

Biochemistry (Easton), 1995-11, Vol.34 (45), p.14868-14873

1995

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Limited proteolysis and active-site labeling studies of soybean lipoxygenase 1

Biochemistry (Easton), 1992-08, Vol.31 (33), p.7700-7706

1992

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Oxygenation of trans polyunsaturated fatty acids by lipoxygenase reveals steric features of the catalytic mechanism

Biochemistry (Easton), 1987-10, Vol.26 (21), p.6880-6884

1987

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Interaction between Non-Heme Iron of Lipoxygenases and Cumene Hydroperoxide: Basis for Enzyme Activation, Inactivation, and Inhibition

Journal of the American Chemical Society, 2010-11, Vol.126 ((7) ; 01, 2004)

2010

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Lipoxygenase-1 Inhibition with a Series of Half-Product Analogs

Bioorganic chemistry, 1996-03, Vol.24 (1), p.95-109

1996

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Crystal Structure of 12-Lipoxygenase Catalytic-Domain-Inhibitor Complex Identifies a Substrate-Binding Channel for Catalysis

Structure-based design of a thiazolidinedione which targets the mitochondrial protein mitoNEET

Identification of novel monoamine oxidase B inhibitors by structure-based virtual screening

Complexes of the Outer Mitochondrial Membrane Protein MitoNEET with Resveratrol-3-Sulfate

Electrospray ionization mass spectrometry of soybean lipoxygenases: N-terminal acetylation, chemical modification, and solution conformation

A scaffold hopping approach to identify novel monoamine oxidase B inhibitors

EPR spectroscopy and electrospray ionization mass spectrometry reveal distinctive features of the iron site in leukocyte 12-lipoxygenase

Secondary Alkyl Hydroperoxides as Inhibitors and Alternate Substrates for Lipoxygenase

Structure–activity relationship and docking studies of thiazolidinedione-type compounds with monoamine oxidase B

Three-Dimensional Structure of a Purple Lipoxygenase

A novel binding assay identifies high affinity ligands to the rosiglitazone binding site of mitoNEET

Interaction between Non-Heme Iron of Lipoxygenases and Cumene Hydroperoxide: Basis for Enzyme Activation, Inactivation, and Inhibition

Structural and Thermochemical Characterization of Lipoxygenase−Catechol Complexes

Peroxy radical cyclization as a model for prostaglandin biosynthesis

Leukocyte 12‐lipoxygenase: expression, purification and physical characterization

Position 713 Is Critical for Catalysis but Not Iron Binding in Soybean Lipoxygenase 3

The formation of cyclic peroxides from unsaturated hydroperoxides: models for prostaglandin biosynthesis

Structures and spectroscopic characteristics of iron(III) diethylenetriaminepentaacetic acid complexes. A non-heme iron(III) complex with relevance to the iron environment in lipoxygenases

The lipoxygenases in developing soybean seeds, their characterization and synthesis in vitro

Role of iron in lipoxygenase catalysis

Catalysis Sensitive Conformational Changes in Soybean Lipoxygenase Revealed by Limited Proteolysis and Monoclonal Antibody Experiments

Limited proteolysis and active-site labeling studies of soybean lipoxygenase 1

Oxygenation of trans polyunsaturated fatty acids by lipoxygenase reveals steric features of the catalytic mechanism

Interaction between Non-Heme Iron of Lipoxygenases and Cumene Hydroperoxide: Basis for Enzyme Activation, Inactivation, and Inhibition

Lipoxygenase-1 Inhibition with a Series of Half-Product Analogs

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