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Cyclometalated Palladium(II) N-Heterocyclic Carbene Complexes: Anticancer Agents for Potent In Vitro Cytotoxicity and In Vivo Tumor Growth Suppression

Angewandte Chemie (International ed.), 2016-09, Vol.55 (39), p.11935-11939

International ed. in English, 2016

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Controlled cellular redox, repressive hemin utilization and adaptive stress responses are crucial to metronidazole tolerance of Porphyromonas gingivalis persisters

Journal of clinical periodontology, 2018-10, Vol.45 (10), p.1211-1221

2018

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Selection of DNA-encoded chemical libraries against endogenous membrane proteins on live cells

Nature chemistry, 2021-01, Vol.13 (1), p.77

2021

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An Antitumor Bis(N‐Heterocyclic Carbene)Platinum(II) Complex That Engages Asparagine Synthetase as an Anticancer Target

Angewandte Chemie (International ed.), 2019-08, Vol.58 (32), p.10914-10918

International ed. in English, 2019

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Luminescent organoplatinum(II) complexes containing bis(N-heterocyclic carbene) ligands selectively target the endoplasmic reticulum and induce potent photo-toxicity

Chemical communications (Cambridge, England), 2013-01, Vol.49 (47), p.5423-5425

2013

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Cyclometalated Gold(III) Complexes Containing N‐Heterocyclic Carbene Ligands Engage Multiple Anti‐Cancer Molecular Targets

Angewandte Chemie (International ed.), 2017-03, Vol.56 (14), p.3892-3896

International ed. in English, 2017

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Glutarylation of Histone H4 Lysine 91 Regulates Chromatin Dynamics

Molecular cell, 2019-11, Vol.76 (4), p.660-675.e9

2019

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An anticancer gold(III)-activated porphyrin scaffold that covalently modifies protein cysteine thiols

Proceedings of the National Academy of Sciences - PNAS, 2020-01, Vol.117 (3), p.1321-1329

2020

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Introducing aldehyde functionality to proteins using ligand-directed affinity labeling

Chemical communications (Cambridge, England), 2020-06, Vol.56 (45), p.6134-6137

2020

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Triazine-pyridine chemistry for protein labelling on tyrosine

Chemical communications (Cambridge, England), 2022-06, Vol.58 (5), p.766-769

2022

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Traceless and Chemoselective Amine Bioconjugation via Phthalimidine Formation in Native Protein Modification

Organic letters, 2016-06, Vol.18 (11), p.2600-2603

2016

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A Chemical Probe for Lysine Malonylation

Angewandte Chemie (International ed.), 2013-04, Vol.52 (18), p.4883-4886

International ed. in English, 2013

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OPA-Based Bifunctional Linker for Protein Labeling and Profiling

Biochemistry (Easton), 2020-01, Vol.59 (2), p.175-178

2020

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Transition Metal Ions: Charge Carriers that Mediate the Electron Capture Dissociation Pathways of Peptides

Journal of the American Society for Mass Spectrometry, 2011-12, Vol.22 (12), p.2232-2245

2011

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Deacylation Mechanism by SIRT2 Revealed in the 1′-SH-2′-O-Myristoyl Intermediate Structure

Cell chemical biology, 2017-03, Vol.24 (3), p.339-345

2017

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Galectin-1 promotes hepatocellular carcinoma and the combined therapeutic effect of OTX008 galectin-1 inhibitor and sorafenib in tumor cells

Journal of experimental & clinical cancer research, 2019-10, Vol.38 (1), p.423-423, Article 423

2019

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Shotgun Proteomics and Quantitative Pathway Analysis of the Mechanisms of Action of Dehydroeffusol, a Bioactive Phytochemical with Anticancer Activity from Juncus effusus

Journal of proteome research, 2018-07, Vol.17 (7), p.2470-2479

2018

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Cyclometalated Palladium(II) N-Heterocyclic Carbene Complexes: Anticancer Agents for Potent In Vitro Cytotoxicity and In Vivo Tumor Growth Suppression

Angewandte Chemie, 2016-09, Vol.128 (39), p.12114-12118

2016

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TPI1‐reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis

Journal of extracellular vesicles, 2021-08, Vol.10 (10), p.e12135-n/a

2021

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Signaling in Insulin-Secreting MIN6 Pseudoislets and Monolayer Cells

Journal of proteome research, 2013-12, Vol.12 (12), p.5954-5962

2013

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The Proteome of Community Living Candida albicans Is Differentially Modulated by the Morphologic and Structural Features of the Bacterial Cohabitants

Microorganisms (Basel), 2020-10, Vol.8 (10), p.1541

2020

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Dysregulation of clathrin promotes thyroid cell growth and contributes to multinodular goiter pathogenesis

Biochimica et biophysica acta, 2015-08, Vol.1852 (8), p.1676-1686

2015

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An Antitumor Bis(N‐Heterocyclic Carbene)Platinum(II) Complex That Engages Asparagine Synthetase as an Anticancer Target

Angewandte Chemie, 2019-08, Vol.131 (32), p.11030-11034

2019

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A Mechanistic Study of the Electron Capture Dissociation of Oligonucleotides

Journal of the American Society for Mass Spectrometry, 2009-02, Vol.20 (2), p.213-226

2009

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Cyclometalated Palladium(II) N-Heterocyclic Carbene Complexes: Anticancer Agents for Potent In Vitro Cytotoxicity and In Vivo Tumor Growth Suppression

Controlled cellular redox, repressive hemin utilization and adaptive stress responses are crucial to metronidazole tolerance of Porphyromonas gingivalis persisters

Selection of DNA-encoded chemical libraries against endogenous membrane proteins on live cells

An Antitumor Bis(N‐Heterocyclic Carbene)Platinum(II) Complex That Engages Asparagine Synthetase as an Anticancer Target

Luminescent organoplatinum(II) complexes containing bis(N-heterocyclic carbene) ligands selectively target the endoplasmic reticulum and induce potent photo-toxicity

Cyclometalated Gold(III) Complexes Containing N‐Heterocyclic Carbene Ligands Engage Multiple Anti‐Cancer Molecular Targets

Glutarylation of Histone H4 Lysine 91 Regulates Chromatin Dynamics

An anticancer gold(III)-activated porphyrin scaffold that covalently modifies protein cysteine thiols

Introducing aldehyde functionality to proteins using ligand-directed affinity labeling

Triazine-pyridine chemistry for protein labelling on tyrosine

Traceless and Chemoselective Amine Bioconjugation via Phthalimidine Formation in Native Protein Modification

A Chemical Probe for Lysine Malonylation

OPA-Based Bifunctional Linker for Protein Labeling and Profiling

Nidogen 1‐Enriched Extracellular Vesicles Facilitate Extrahepatic Metastasis of Liver Cancer by Activating Pulmonary Fibroblasts to Secrete Tumor Necrosis Factor Receptor 1

Transition Metal Ions: Charge Carriers that Mediate the Electron Capture Dissociation Pathways of Peptides

Deacylation Mechanism by SIRT2 Revealed in the 1′-SH-2′-O-Myristoyl Intermediate Structure

Galectin-1 promotes hepatocellular carcinoma and the combined therapeutic effect of OTX008 galectin-1 inhibitor and sorafenib in tumor cells

Shotgun Proteomics and Quantitative Pathway Analysis of the Mechanisms of Action of Dehydroeffusol, a Bioactive Phytochemical with Anticancer Activity from Juncus effusus

Cyclometalated Palladium(II) N-Heterocyclic Carbene Complexes: Anticancer Agents for Potent In Vitro Cytotoxicity and In Vivo Tumor Growth Suppression

TPI1‐reduced extracellular vesicles mediated by Rab20 downregulation promotes aerobic glycolysis to drive hepatocarcinogenesis

Signaling in Insulin-Secreting MIN6 Pseudoislets and Monolayer Cells

The Proteome of Community Living Candida albicans Is Differentially Modulated by the Morphologic and Structural Features of the Bacterial Cohabitants

Dysregulation of clathrin promotes thyroid cell growth and contributes to multinodular goiter pathogenesis

An Antitumor Bis(N‐Heterocyclic Carbene)Platinum(II) Complex That Engages Asparagine Synthetase as an Anticancer Target

A Mechanistic Study of the Electron Capture Dissociation of Oligonucleotides

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