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Targeting extracellular glycans: tuning multimeric boronic acids for pathogen-selective killing of Mycobacterium tuberculosis

Chemical science (Cambridge), 2019-06, Vol.10 (23), p.5935-5942

2019

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Multivalent Antimicrobial Polymer Nanoparticles Target Mycobacteria and Gram-Negative Bacteria by Distinct Mechanisms

Biomacromolecules, 2018-01, Vol.19 (1), p.256-264

2018

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Evaluation of the Antimicrobial Activity of Cationic Polymers against Mycobacteria: Toward Antitubercular Macromolecules

Biomacromolecules, 2017-05, Vol.18 (5), p.1592-1599

2017

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Structural and functional determination of homologs of the Mycobacterium tuberculosis N-acetylglucosamine-6-phosphate deacetylase (NagA)

The Journal of biological chemistry, 2018-06, Vol.293 (25), p.9770-9783

2018

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Structural and functional analysis of the solute-binding protein UspC from Mycobacterium tuberculosis that is specific for amino sugars

Open biology, 2016-06, Vol.6 (6), p.160105

2016

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Biochemical and phenotypic characterisation of the Mycobacterium smegmatis transporter UspABC

Cell surface (Amsterdam), 2021-12, Vol.7, p.100052-100052, Article 100052

2021

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Exploration of piperidinols as potential antitubercular agents

Molecules (Basel, Switzerland), 2014-10, Vol.19 (10), p.16274-16290

2014

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Divergence of Cofactor Recognition across Evolution: Coenzyme A Binding in a Prokaryotic Arylamine N-Acetyltransferase

Journal of molecular biology, 2008-01, Vol.375 (1), p.178-191

2008

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Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages

PloS one, 2012-12, Vol.7 (12), p.e52790

2012

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Temperature stability of proteins essential for the intracellular survival of Mycobacterium tuberculosis

Biochemical journal, 2009-03, Vol.418 (2), p.369-378

2009

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Binding of the anti‐tubercular drug isoniazid to the arylamine N‐acetyltransferase protein from Mycobacterium smegmatis

Protein science, 2005-03, Vol.14 (3), p.775-782

2005

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Arylamine N-acetyltransferases in mycobacteria

Current drug metabolism, 2008-07, Vol.9 (6), p.510-519

2008

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Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme

Open biology, 2012-01, Vol.2 (1), p.110026-110026

2012

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Physicochemical properties and Mycobacterium tuberculosis transporters: keys to efficacious antitubercular drugs?

RSC medicinal chemistry, 2020-12, Vol.12 (1), p.43-56

2020

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Physicochemical properties and transporters: keys to efficacious antitubercular drugs?

RSC medicinal chemistry, 2021-02, Vol.12 (1), p.43-56

2021

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Dimeric benzoboroxoles for targeted activity against

Organic & biomolecular chemistry, 2019-11, Vol.17 (43), p.9524-9528

2019

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Targeting extracellular glycans: tuning multimeric boronic acids for pathogen-selective killing of Mycobacterium tuberculosis† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc00415g

Chemical science (Cambridge), 2019-05, Vol.10 (23), p.5935-5942

2019

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Dimeric benzoboroxoles for targeted activity against Mycobacterium tuberculosis

Organic & biomolecular chemistry, 2019-11, Vol.17 (43), p.9524-9528

2019

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Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis

Science (American Association for the Advancement of Science), 2009-05, Vol.324 (5928), p.801-804

2009

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Supramolecular organization and dynamics of mannosylated phosphatidylinositol lipids in the mycobacterial plasma membrane

Proceedings of the National Academy of Sciences - PNAS, 2023-01, Vol.120 (5), p.e2212755120-e2212755120

2023

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Supramolecular organisation and dynamics of mannosylated phosphatidylinositol lipids in the mycobacterial plasma membrane

Biophysical journal, 2023-02, Vol.122 (3), p.136a-136a

2023

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Imaging of antitubercular dimeric boronic acids at the mycobacterial cell surface by click-probe capture

Chemical communications (Cambridge, England), 2022-08, Vol.58 (67), p.9361-9364

2022

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Asymmetric trehalose analogues to probe disaccharide processing pathways in mycobacteria

Organic & biomolecular chemistry, 2020-05, Vol.18 (18), p.367-3612

2020

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Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis

Science translational medicine, 2012-09, Vol.4 (150), p.150ra121

2012

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Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profileElectronic supplementary information (ESI) available: Experimental procedures. See DOI: 10.1039/c5mb00720h

2016-01

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Targeting extracellular glycans: tuning multimeric boronic acids for pathogen-selective killing of Mycobacterium tuberculosis

Multivalent Antimicrobial Polymer Nanoparticles Target Mycobacteria and Gram-Negative Bacteria by Distinct Mechanisms

Evaluation of the Antimicrobial Activity of Cationic Polymers against Mycobacteria: Toward Antitubercular Macromolecules

Structural and functional determination of homologs of the Mycobacterium tuberculosis N-acetylglucosamine-6-phosphate deacetylase (NagA)

Structural and functional analysis of the solute-binding protein UspC from Mycobacterium tuberculosis that is specific for amino sugars

Biochemical and phenotypic characterisation of the Mycobacterium smegmatis transporter UspABC

Exploration of piperidinols as potential antitubercular agents

Divergence of Cofactor Recognition across Evolution: Coenzyme A Binding in a Prokaryotic Arylamine N-Acetyltransferase

Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages

Temperature stability of proteins essential for the intracellular survival of Mycobacterium tuberculosis

Binding of the anti‐tubercular drug isoniazid to the arylamine N‐acetyltransferase protein from Mycobacterium smegmatis

Arylamine N-acetyltransferases in mycobacteria

Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme

Physicochemical properties and Mycobacterium tuberculosis transporters: keys to efficacious antitubercular drugs?

Physicochemical properties and transporters: keys to efficacious antitubercular drugs?

Dimeric benzoboroxoles for targeted activity against

Targeting extracellular glycans: tuning multimeric boronic acids for pathogen-selective killing of Mycobacterium tuberculosis† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc00415g

Dimeric benzoboroxoles for targeted activity against Mycobacterium tuberculosis

Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis

Supramolecular organization and dynamics of mannosylated phosphatidylinositol lipids in the mycobacterial plasma membrane

Supramolecular organisation and dynamics of mannosylated phosphatidylinositol lipids in the mycobacterial plasma membrane

Imaging of antitubercular dimeric boronic acids at the mycobacterial cell surface by click-probe capture

Asymmetric trehalose analogues to probe disaccharide processing pathways in mycobacteria

Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis

Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profileElectronic supplementary information (ESI) available: Experimental procedures. See DOI: 10.1039/c5mb00720h

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