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Molecular engineering of a minimal E-cadherin inhibitor protein derived from Clostridium botulinum hemagglutinin

The Journal of biological chemistry, 2023-03, Vol.299 (3), p.102944, Article 102944

2023

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Functional Analysis of Botulinum Hemagglutinin (HA)

Methods in molecular biology (Clifton, N.J.), 2020, Vol.2132, p.191

2020

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Gut-derived Enterococcus faecium from ulcerative colitis patients promotes colitis in a genetically susceptible mouse host

Genome Biology, 2019-11, Vol.20 (1), p.252-252, Article 252

2019

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Effects of antibiotics on the viability of and toxin production by Clostridium botulinum

Microbiology and immunology, 2021-10, Vol.65 (10), p.432-437

2021

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Botulinum Hemagglutinin: Critical Protein for Adhesion and Absorption of Neurotoxin Complex in Host Intestine

Methods in molecular biology (Clifton, N.J.), 2020, Vol.2132, p.183

2020

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Translocation and dissemination of botulinum neurotoxin from the intestinal tract

Toxicon (Oxford), 2018-06, Vol.147, p.13-18

2018

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Growth prolongation of human induced pluripotent stem cell aggregate in three-dimensional suspension culture system by addition of botulinum hemagglutinin

Journal of bioscience and bioengineering, 2024-02, Vol.137 (2), p.141-148

2024

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Crystal Structure of Clostridium botulinum Whole Hemagglutinin Reveals a Huge Triskelion-shaped Molecular Complex

The Journal of biological chemistry, 2013-12, Vol.288 (49), p.35617-35625

2013

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Maintenance of an undifferentiated state of human-induced pluripotent stem cells through botulinum hemagglutinin-mediated regulation of cell behavior

Journal of bioscience and bioengineering, 2019-06, Vol.127 (6), p.744-751

2019

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Patient-derived Enterococcus faecium with inflammatory genotypes promote colitis

Journal of gastroenterology, 2022-10, Vol.57 (10), p.770-783

2022

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Functional dissection of the Clostridium botulinum type B hemagglutinin complex: identification of the carbohydrate and E-cadherin binding sites

PloS one, 2014-10, Vol.9 (10), p.e111170

2014

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Botulinum toxin A complex exploits intestinal M cells to enter the host and exert neurotoxicity

Nature communications, 2015-02, Vol.6 (1), p.6255, Article 6255

2015

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Botulinum hemagglutinin disrupts the intercellular epithelial barrier by directly binding E-cadherin

The Journal of cell biology, 2010-05, Vol.189 (4), p.691-700

2010

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Botulinum neurotoxin X lacks potency in mice and in human neurons

mBio, 2024-02, Vol.15 (3), p.e0310623

2024

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Botulinum hemagglutinin-mediated selective removal of cells deviating from the undifferentiated state in hiPSC colonies

Scientific reports, 2017-03, Vol.7 (1), p.93-12, Article 93

2017

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Multivalency effects of hemagglutinin component of type B botulinum neurotoxin complex on epithelial barrier disruption

Microbiology and immunology, 2018-02, Vol.62 (2), p.80-89

2018

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Rare toxin A-negative and toxin B-positive strain of Clostridioides difficile from Japan lacking a complete tcdA gene

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2022-05, Vol.28 (5), p.651-656

2022

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Membrane Vesicles Derived From Clostridium botulinum and Related Clostridial Species Induce Innate Immune Responses via MyD88/TRIF Signaling in vitro

Frontiers in microbiology, 2022-02, Vol.13, p.720308-720308

2022

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Oral Corticosteroids Impair Mucin Production and Alter the Posttransplantation Microbiota in the Gut

Digestion, 2022-01, Vol.103 (4), p.269-286

2022

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Clostridium botulinum type C hemagglutinin affects the morphology and viability of cultured mammalian cells via binding to the ganglioside GM3

The FEBS journal, 2015-09, Vol.282 (17), p.3334-3347

2015

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Disruption of the epithelial barrier by botulinum haemagglutinin (HA) proteins - differences in cell tropism and the mechanism of action between HA proteins of types A or B, and HA proteins of type C

Microbiology (Society for General Microbiology), 2009-01, Vol.155 (Pt 1), p.35-45

2009

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Fully Human Monoclonal Antibodies Effectively Neutralizing Botulinum Neurotoxin Serotype B

Toxins, 2020-05, Vol.12 (5), p.302

2020

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Chronic liver disease enables gut Enterococcus faecalis colonization to promote liver carcinogenesis

Nature cancer, 2021-10, Vol.2 (10), p.1039-1054

2021

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HA proteins of botulinum toxin disrupt intestinal epithelial intercellular junctions to increase toxin absorption

Cellular microbiology, 2008-02, Vol.10 (2), p.355-364

2008

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A Simple and Robust Method for Culturing Human‐Induced Pluripotent Stem Cells in an Undifferentiated State Using Botulinum Hemagglutinin

Biotechnology journal, 2018-02, Vol.13 (2), p.n/a

2018

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Molecular engineering of a minimal E-cadherin inhibitor protein derived from Clostridium botulinum hemagglutinin

Functional Analysis of Botulinum Hemagglutinin (HA)

Gut-derived Enterococcus faecium from ulcerative colitis patients promotes colitis in a genetically susceptible mouse host

Effects of antibiotics on the viability of and toxin production by Clostridium botulinum

Botulinum Hemagglutinin: Critical Protein for Adhesion and Absorption of Neurotoxin Complex in Host Intestine

Translocation and dissemination of botulinum neurotoxin from the intestinal tract

Growth prolongation of human induced pluripotent stem cell aggregate in three-dimensional suspension culture system by addition of botulinum hemagglutinin

Crystal Structure of Clostridium botulinum Whole Hemagglutinin Reveals a Huge Triskelion-shaped Molecular Complex

Maintenance of an undifferentiated state of human-induced pluripotent stem cells through botulinum hemagglutinin-mediated regulation of cell behavior

Patient-derived Enterococcus faecium with inflammatory genotypes promote colitis

Functional dissection of the Clostridium botulinum type B hemagglutinin complex: identification of the carbohydrate and E-cadherin binding sites

Botulinum toxin A complex exploits intestinal M cells to enter the host and exert neurotoxicity

Botulinum hemagglutinin disrupts the intercellular epithelial barrier by directly binding E-cadherin

Botulinum neurotoxin X lacks potency in mice and in human neurons

Botulinum hemagglutinin-mediated selective removal of cells deviating from the undifferentiated state in hiPSC colonies

Multivalency effects of hemagglutinin component of type B botulinum neurotoxin complex on epithelial barrier disruption

Rare toxin A-negative and toxin B-positive strain of Clostridioides difficile from Japan lacking a complete tcdA gene

Membrane Vesicles Derived From Clostridium botulinum and Related Clostridial Species Induce Innate Immune Responses via MyD88/TRIF Signaling in vitro

Oral Corticosteroids Impair Mucin Production and Alter the Posttransplantation Microbiota in the Gut

Clostridium botulinum type C hemagglutinin affects the morphology and viability of cultured mammalian cells via binding to the ganglioside GM3

Disruption of the epithelial barrier by botulinum haemagglutinin (HA) proteins - differences in cell tropism and the mechanism of action between HA proteins of types A or B, and HA proteins of type C

Fully Human Monoclonal Antibodies Effectively Neutralizing Botulinum Neurotoxin Serotype B

Chronic liver disease enables gut Enterococcus faecalis colonization to promote liver carcinogenesis

HA proteins of botulinum toxin disrupt intestinal epithelial intercellular junctions to increase toxin absorption

A Simple and Robust Method for Culturing Human‐Induced Pluripotent Stem Cells in an Undifferentiated State Using Botulinum Hemagglutinin

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