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Conversion of human fibroblasts into functional cardiomyocytes by small molecules

Science (American Association for the Advancement of Science), 2016-06, Vol.352 (6290), p.1216-1220

2016

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Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness

Proceedings of the National Academy of Sciences - PNAS, 2015-10, Vol.112 (41), p.12705-12710

2015

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Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis

Cell, 2016-12, Vol.167 (7), p.1734-1749.e22

2016

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Single cell qPCR reveals that additional HAND2 and microRNA-1 facilitate the early reprogramming progress of seven-factor-induced human myocytes

PloS one, 2017-08, Vol.12 (8), p.e0183000-e0183000

2017

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Direct Reprogramming of Fibroblasts into Cardiomyocytes for Cardiac Regenerative Medicine

Circulation Journal, 2015/01/23, Vol.79(2), pp.245-254

2015

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Ventricular arrhythmias in mouse models of diabetic kidney disease

Scientific reports, 2021-10, Vol.11 (1), p.20570-20570, Article 20570

2021

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Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes

PloS one, 2011-11, Vol.6 (11), p.e27417-e27417

2011

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Direct reprogramming of human fibroblasts toward a cardiomyocyte-like state

Stem cell reports, 2013-09, Vol.1 (3), p.235-247

2013

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Rewiring of 3D Chromatin Topology Orchestrates Transcriptional Reprogramming and the Development of Human Dilated Cardiomyopathy

Circulation (New York, N.Y.), 2022-05, Vol.145 (22), p.1663-1683

2022

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Mechanism-Based Facilitated Maturation of Human Pluripotent Stem Cell–Derived Cardiomyocytes

Circulation. Arrhythmia and electrophysiology, 2013-02, Vol.6 (1), p.191-201

2013

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Ameliorating the Fibrotic Remodeling of the Heart through Direct Cardiac Reprogramming

Cells (Basel, Switzerland), 2019-07, Vol.8 (7), p.679

2019

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Functional Sarcoplasmic Reticulum for Calcium Handling of Human Embryonic Stem Cell‐Derived Cardiomyocytes: Insights for Driven Maturation

Stem cells (Dayton, Ohio), 2007-12, Vol.25 (12), p.3038-3044

2007

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S-phase Synchronization Facilitates the Early Progression of Induced-Cardiomyocyte Reprogramming through Enhanced Cell-Cycle Exit

International journal of molecular sciences, 2018-05, Vol.19 (5), p.1364

2018

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A Heart Failure-Associated SCN5A Splice Variant Leads to a Reduction in Sodium Current Through Coupled-Gating With the Wild-Type Channel

Frontiers in physiology, 2021-03, Vol.12, p.661429-661429

2021

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Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors

Cell, 2010-08, Vol.142 (3), p.375-386

2010

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Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes

PloS one, 2008-10, Vol.3 (10), p.e3474

2008

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Inhibition of CREB-CBP Signaling Improves Fibroblast Plasticity for Direct Cardiac Reprogramming

Cells (Basel, Switzerland), 2021-06, Vol.10 (7), p.1572

2021

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In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

Nature (London), 2012-05, Vol.485 (7400), p.593-598

2012

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Adipogenic Signaling Promotes Arrhythmia Substrates before Structural Abnormalities in TMEM43 ARVC

Journal of personalized medicine, 2022-10, Vol.12 (10), p.1680

2022

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Genetically Modified Porcine Mesenchymal Stem Cells by Lentiviral Tbx18 Create a Biological Pacemaker

Stem cells international, 2019, Vol.2019 (2019), p.1-9

2019

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Production of Cardiomyocyte-Like Cells by Fibroblast Reprogramming with Defined Factors

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2239, p.33

2021

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Bmi1 Is a Key Epigenetic Barrier to Direct Cardiac Reprogramming

Cell stem cell, 2016-03, Vol.18 (3), p.382-395

2016

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A Singular Role of IK1 Promoting the Development of Cardiac Automaticity during Cardiomyocyte Differentiation by IK1 –Induced Activation of Pacemaker Current

Stem cell reviews, 2017-10, Vol.13 (5), p.631-643

2017

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Multilayer control of cardiac electrophysiology by microRNAs

Journal of molecular and cellular cardiology, 2022-05, Vol.166, p.107-115

2022

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Reprogramming of mouse fibroblasts into cardiomyocyte-like cells in vitro

Nature protocols, 2013-06, Vol.8 (6), p.1204-1215

2013

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Conversion of human fibroblasts into functional cardiomyocytes by small molecules

Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness

Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis

Single cell qPCR reveals that additional HAND2 and microRNA-1 facilitate the early reprogramming progress of seven-factor-induced human myocytes

Direct Reprogramming of Fibroblasts into Cardiomyocytes for Cardiac Regenerative Medicine

Ventricular arrhythmias in mouse models of diabetic kidney disease

Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes

Direct reprogramming of human fibroblasts toward a cardiomyocyte-like state

Rewiring of 3D Chromatin Topology Orchestrates Transcriptional Reprogramming and the Development of Human Dilated Cardiomyopathy

Mechanism-Based Facilitated Maturation of Human Pluripotent Stem Cell–Derived Cardiomyocytes

Ameliorating the Fibrotic Remodeling of the Heart through Direct Cardiac Reprogramming

Functional Sarcoplasmic Reticulum for Calcium Handling of Human Embryonic Stem Cell‐Derived Cardiomyocytes: Insights for Driven Maturation

S-phase Synchronization Facilitates the Early Progression of Induced-Cardiomyocyte Reprogramming through Enhanced Cell-Cycle Exit

A Heart Failure-Associated SCN5A Splice Variant Leads to a Reduction in Sodium Current Through Coupled-Gating With the Wild-Type Channel

Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors

Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes

Inhibition of CREB-CBP Signaling Improves Fibroblast Plasticity for Direct Cardiac Reprogramming

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

Adipogenic Signaling Promotes Arrhythmia Substrates before Structural Abnormalities in TMEM43 ARVC

Genetically Modified Porcine Mesenchymal Stem Cells by Lentiviral Tbx18 Create a Biological Pacemaker

Production of Cardiomyocyte-Like Cells by Fibroblast Reprogramming with Defined Factors

Bmi1 Is a Key Epigenetic Barrier to Direct Cardiac Reprogramming

A Singular Role of IK1 Promoting the Development of Cardiac Automaticity during Cardiomyocyte Differentiation by IK1 –Induced Activation of Pacemaker Current

Multilayer control of cardiac electrophysiology by microRNAs

Reprogramming of mouse fibroblasts into cardiomyocyte-like cells in vitro

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