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Visualizing reactive astrocytes: Positron emission tomography imaging ligands for imidazoline‐2 binding sites

View (Beijing, China), 2023-12, Vol.4 (6), p.n/a

2023

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[18F]MAGL-4-11 positron emission tomography molecular imaging of monoacylglycerol lipase changes in preclinical liver fibrosis models

Acta pharmaceutica Sinica. B, 2022-01, Vol.12 (1), p.308-315

2022

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Synthesis and Preliminary Evaluation of [11C]GNE‐1023 as a Potent PET Probe for Imaging Leucine‐Rich Repeat Kinase 2 (LRRK2) in Parkinson's Disease

ChemMedChem, 2019-09, Vol.14 (17), p.1580-1585

2019

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Design, Synthesis, and Evaluation of 18F‑Labeled Monoacylglycerol Lipase Inhibitors as Novel Positron Emission Tomography Probes

Journal of medicinal chemistry, 2019-10, Vol.62 (19), p.8866-8872

2019

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Discovery and development of brain-penetrant 18F-labeled radioligands for neuroimaging of the sigma-2 receptors

Acta pharmaceutica Sinica. B, 2022-03, Vol.12 (3), p.1406-1415

2022

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Synthesis, pharmacology and preclinical evaluation of 11C-labeled 1,3-dihydro-2H-benzo[d]imidazole-2-ones for imaging γ8-dependent transmembrane AMPA receptor regulatory protein

European journal of medicinal chemistry, 2018-09, Vol.157, p.898-908

2018

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Synthesis and Preliminary Evaluations of a Triazole-Cored Antagonist as a PET Imaging Probe ([18F]N2B-0518) for GluN2B Subunit in the Brain

ACS chemical neuroscience, 2019-05, Vol.10 (5), p.2263-2275

2019

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Highly Sensitive Near-Infrared Fluorophores for in Vivo Detection of Amyloid‑β Plaques in Alzheimer’s Disease

Journal of medicinal chemistry, 2015-09, Vol.58 (17), p.6972-6983

2015

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Evaluation of molecules based on the electron donor-acceptor architecture as near-infrared β-amyloidal-targeting probes

Chemical communications (Cambridge, England), 2014-10, Vol.50 (80), p.11875-11878

2014

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Amyloid‑β Deposits Target Efficient Near-Infrared Fluorescent Probes: Synthesis, in Vitro Evaluation, and in Vivo Imaging

Analytical chemistry (Washington), 2016-02, Vol.88 (3), p.1944-1950

2016

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Positron Emission Tomography (PET) Ligand Development for Ionotropic Glutamate Receptors: Challenges and Opportunities for Radiotracer Targeting N-Methyl-d-aspartate (NMDA), α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA), and Kainate Receptors

Journal of medicinal chemistry, 2019-01, Vol.62 (2), p.403-419

2019

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Rational design of molecular rotor-based fluorescent probes with bi-aromatic rings for efficient in vivo detection of amyloid-β plaques in Alzheimer's disease

European journal of medicinal chemistry, 2022-12, Vol.243, p.114715-114715, Article 114715

2022

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Near-Infrared Fluorescent Probes with Rotatable Polyacetylene Chains for the Detection of Amyloid‑β Plaques

The journal of physical chemistry. B, 2021-01, Vol.125 (2), p.497-506

2021

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Positron Emission Tomography (PET) Imaging Tracers for Serotonin Receptors

Journal of medicinal chemistry, 2022-08, Vol.65 (16), p.10755-10808

2022

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Visualizing Tumors in Real Time: A Highly Sensitive PSMA Probe for NIR-II Imaging and Intraoperative Tumor Resection

Journal of medicinal chemistry, 2021-06, Vol.64 (11), p.7735-7745

2021

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18F-Labeled o‑aminopyridyl alkynyl radioligands targeting colony-stimulating factor 1 receptor for neuroinflammation imaging

Bioorganic & medicinal chemistry, 2023-04, Vol.83, p.117233-117233, Article 117233

2023

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D‑π-A-Based Trisubstituted Alkenes as Environmentally Sensitive Fluorescent Probes to Detect Lewy Pathologies

Analytical chemistry (Washington), 2022-11, Vol.94 (44), p.15261-15269

2022

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The synthesis and evaluation of near-infrared probes with barbituric acid acceptors for in vivo detection of amyloid plaques

Chemical communications (Cambridge, England), 2015-07, Vol.51 (58), p.11665-11668

2015

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Compounds for imaging amyloid-β deposits in an Alzheimer's brain: a patent review

Expert opinion on therapeutic patents, 2015-04, Vol.25 (4), p.413-423

2015

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Half-curcumin analogues as PET imaging probes for amyloid beta species

Chemical communications (Cambridge, England), 2019-03, Vol.55 (25), p.3630-3633

2019

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Imaging Leucine-Rich Repeat Kinase 2 In Vivo with 18F‑Labeled Positron Emission Tomography Ligand

Journal of medicinal chemistry, 2023-02, Vol.66 (3), p.1712-1724

2023

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Radiosynthesis and preclinical evaluation of a novel 18F-labeled MAGL inhibitor PF-06795071 for MAGL imaging

The Journal of nuclear medicine (1978), 2019-05, Vol.60

2019

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Positron Emission Tomography (PET) Ligand Development for Ionotropic Glutamate Receptors: Challenges and Opportunities for Radiotracer Targeting N -Methyl- d -aspartate (NMDA), α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA), and Kainate Receptors: Miniperspective

Journal of medicinal chemistry, 2019-01, Vol.62 (2), p.403-419

2019

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Imaging Cholinergic Receptors in the Brain by Positron Emission Tomography

Journal of medicinal chemistry, 2023-08, Vol.66 (16), p.10889-10916

2023

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Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a “Tail Switching” Strategy on a Piperazinyl Azetidine Skeleton

Visualizing reactive astrocytes: Positron emission tomography imaging ligands for imidazoline‐2 binding sites

[18F]MAGL-4-11 positron emission tomography molecular imaging of monoacylglycerol lipase changes in preclinical liver fibrosis models

Synthesis and Preliminary Evaluation of [11C]GNE‐1023 as a Potent PET Probe for Imaging Leucine‐Rich Repeat Kinase 2 (LRRK2) in Parkinson's Disease

Design, Synthesis, and Evaluation of 18F‑Labeled Monoacylglycerol Lipase Inhibitors as Novel Positron Emission Tomography Probes

Discovery and development of brain-penetrant 18F-labeled radioligands for neuroimaging of the sigma-2 receptors

Synthesis, pharmacology and preclinical evaluation of 11C-labeled 1,3-dihydro-2H-benzo[d]imidazole-2-ones for imaging γ8-dependent transmembrane AMPA receptor regulatory protein

Synthesis and Preliminary Evaluations of a Triazole-Cored Antagonist as a PET Imaging Probe ([18F]N2B-0518) for GluN2B Subunit in the Brain

Highly Sensitive Near-Infrared Fluorophores for in Vivo Detection of Amyloid‑β Plaques in Alzheimer’s Disease

Evaluation of molecules based on the electron donor-acceptor architecture as near-infrared β-amyloidal-targeting probes

Amyloid‑β Deposits Target Efficient Near-Infrared Fluorescent Probes: Synthesis, in Vitro Evaluation, and in Vivo Imaging

Positron Emission Tomography (PET) Ligand Development for Ionotropic Glutamate Receptors: Challenges and Opportunities for Radiotracer Targeting N-Methyl-d-aspartate (NMDA), α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA), and Kainate Receptors

Rational design of molecular rotor-based fluorescent probes with bi-aromatic rings for efficient in vivo detection of amyloid-β plaques in Alzheimer's disease

Near-Infrared Fluorescent Probes with Rotatable Polyacetylene Chains for the Detection of Amyloid‑β Plaques

Positron Emission Tomography (PET) Imaging Tracers for Serotonin Receptors

Visualizing Tumors in Real Time: A Highly Sensitive PSMA Probe for NIR-II Imaging and Intraoperative Tumor Resection

18F-Labeled o‑aminopyridyl alkynyl radioligands targeting colony-stimulating factor 1 receptor for neuroinflammation imaging

D‑π-A-Based Trisubstituted Alkenes as Environmentally Sensitive Fluorescent Probes to Detect Lewy Pathologies

The synthesis and evaluation of near-infrared probes with barbituric acid acceptors for in vivo detection of amyloid plaques

Compounds for imaging amyloid-β deposits in an Alzheimer's brain: a patent review

Half-curcumin analogues as PET imaging probes for amyloid beta species

Imaging Leucine-Rich Repeat Kinase 2 In Vivo with 18F‑Labeled Positron Emission Tomography Ligand

Radiosynthesis and preclinical evaluation of a novel 18F-labeled MAGL inhibitor PF-06795071 for MAGL imaging

Positron Emission Tomography (PET) Ligand Development for Ionotropic Glutamate Receptors: Challenges and Opportunities for Radiotracer Targeting N -Methyl- d -aspartate (NMDA), α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA), and Kainate Receptors: Miniperspective

Imaging Cholinergic Receptors in the Brain by Positron Emission Tomography

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