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4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors

Nature medicine, 2015-06, Vol.21 (6), p.581-590

2015

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4-1BBL-Expressing aAPCs Attenuate IL-15-Induced NK Cell Expansion and Cytokine Production In Vitro but Induce NK Cell-Mediated Gvhd In Vivo

Blood, 2010-11, Vol.116 (21), p.2536-2536

2010

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41BBL-Based Activation and Expansion of Autologous Natural Killer Cells Results in Enhanced Activity Against Leukemia Including ALL

Blood, 2014-12, Vol.124 (21), p.2293-2293

2014

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6 - Chimeric Antigen Receptor T-Cell (CAR-T) Therapy Can Render Patients with ALL Into PCR-Negative Remission and Can be an Effective Bridge to Transplant (HCT)

Biology of blood and marrow transplantation, 2018-03, Vol.24 (3), p.S25-S26

2018

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65 - Efficacy and Kinetics of CAR-T Cell Therapy in Children and Young Adults with Extramedullary Acute Lymphoblastic Leukemia (ALL) and Non-Hodgkin Lymphoma (NHL)

Biology of blood and marrow transplantation, 2018-03, Vol.24 (3), p.S75-S76

2018

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IL-7 administration to humans leads to expansion of CD8+ and CD4+ cells but a relative decrease of CD4+ T-regulatory cells

Journal of immunotherapy (1997), 2006-05, Vol.29 (3), p.313-319

2006

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IL-7 comes of age

Blood, 2006-04, Vol.107 (7), p.2587-2588

Fry, Terry J.

2006

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IL-7 in allogeneic transplant: Clinical promise and potential pitfalls

Leukemia & lymphoma, 2006-07, Vol.47 (7), p.1222-1228

2006

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IL-7 increases both thymic-dependent and thymic-independent T-cell regeneration after bone marrow transplantation

Blood, 2001-03, Vol.97 (5), p.1491-1497

2001

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IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected nonhuman primates

Blood, 2003-03, Vol.101 (6), p.2294-2299

2003

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Absence of Replication-Competent Lentivirus in the Clinic: Analysis of Infused T Cell Products

Molecular therapy, 2018-01, Vol.26 (1), p.280-288

2018

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Absence of STAT1 in donor-derived plasmacytoid dendritic cells results in increased STAT3 and attenuates murine GVHD

Blood, 2014-09, Vol.124 (12), p.1976-1986

2014

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Abstract 1332: Pediatric sarcomas are infiltrated with myeloid derived suppressive cells

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.1332-1332

2010

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Abstract 1534: Analysis of CAR 41-BB versus CD28 co-stimulatory domains exposes emergence of extramedullary disease in acute myeloid leukemia

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.1534-1534

2018

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Abstract 1630: FLT3 chimeric antigen receptor T cell therapy induces B to T cell lineage switch in infant acute lymphoblastic leukemia

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.1630-1630

2018

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Abstract 2372: Inflammatory cytokine induced TSLP from bone marrow niches contributes to relapse of high risk TSLPR overexpressing acute lymphoblastic leukemia

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.2372-2372

2015

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Abstract 2734: Modulation of resting T cell status to enhance transduction and CAR T expansion following exposure to CD8-targeted fusosomes

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.2734-2734

2023

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Abstract 2735: Development of a novel, fully human anti-CD19 chimeric antigen receptor for in vivo delivery via CD8-targeted fusosome

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.2735-2735

2023

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Abstract 3143: Alternative splicing of CD19 mRNA in leukemias escaping CART-19 immunotherapy eliminates the cognate epitope and contributes to treatment failure

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.3143-3143

2015

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Abstract 4091: Engineered hypoimmune CAR T cells provide lasting tumor control in immunocompetent allogeneic humanized mice even with re-challenge

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.4091-4091

2023

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Abstract 4231: Factors predictive of CAR T cell associated hemophagocytic lymphohistiocytosis (HLH)

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.4231-4231

2020

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Abstract 4702: 4-1BB costimulation ameliorates exhaustion and prolongs in vivo persistence of chimeric antigen receptor (CAR) expressing T cells

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.4702-4702

2015

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Abstract 4705: Late ALL relapse following CD19 CAR immune-pressure demonstrates reversible pan-antigen loss

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.4705-4705

2015

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Abstract 5598: Engineered hypoimmune allogeneic CAR T cells as potential off-the-shelf CAR T cell immunotherapies

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.5598-5598

2022

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4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors

4-1BBL-Expressing aAPCs Attenuate IL-15-Induced NK Cell Expansion and Cytokine Production In Vitro but Induce NK Cell-Mediated Gvhd In Vivo

41BBL-Based Activation and Expansion of Autologous Natural Killer Cells Results in Enhanced Activity Against Leukemia Including ALL

546 - Cytomegalovirus (CMV) Infection and Disease Incidence and Risk Factors Across Diverse Hematopoietic Cell Transplantation (HCT) Platforms Using a Standardized Monitoring and Treatment Approach: A Comprehensive Evaluation From a Single Institution

6 - Chimeric Antigen Receptor T-Cell (CAR-T) Therapy Can Render Patients with ALL Into PCR-Negative Remission and Can be an Effective Bridge to Transplant (HCT)

65 - Efficacy and Kinetics of CAR-T Cell Therapy in Children and Young Adults with Extramedullary Acute Lymphoblastic Leukemia (ALL) and Non-Hodgkin Lymphoma (NHL)

IL-7 administration to humans leads to expansion of CD8+ and CD4+ cells but a relative decrease of CD4+ T-regulatory cells

IL-7 comes of age

IL-7 in allogeneic transplant: Clinical promise and potential pitfalls

IL-7 increases both thymic-dependent and thymic-independent T-cell regeneration after bone marrow transplantation

IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected nonhuman primates

Absence of Replication-Competent Lentivirus in the Clinic: Analysis of Infused T Cell Products

Absence of STAT1 in donor-derived plasmacytoid dendritic cells results in increased STAT3 and attenuates murine GVHD

Abstract 1332: Pediatric sarcomas are infiltrated with myeloid derived suppressive cells

Abstract 1534: Analysis of CAR 41-BB versus CD28 co-stimulatory domains exposes emergence of extramedullary disease in acute myeloid leukemia

Abstract 1630: FLT3 chimeric antigen receptor T cell therapy induces B to T cell lineage switch in infant acute lymphoblastic leukemia

Abstract 2372: Inflammatory cytokine induced TSLP from bone marrow niches contributes to relapse of high risk TSLPR overexpressing acute lymphoblastic leukemia

Abstract 2734: Modulation of resting T cell status to enhance transduction and CAR T expansion following exposure to CD8-targeted fusosomes

Abstract 2735: Development of a novel, fully human anti-CD19 chimeric antigen receptor for in vivo delivery via CD8-targeted fusosome

Abstract 3143: Alternative splicing of CD19 mRNA in leukemias escaping CART-19 immunotherapy eliminates the cognate epitope and contributes to treatment failure

Abstract 4091: Engineered hypoimmune CAR T cells provide lasting tumor control in immunocompetent allogeneic humanized mice even with re-challenge

Abstract 4231: Factors predictive of CAR T cell associated hemophagocytic lymphohistiocytosis (HLH)

Abstract 4702: 4-1BB costimulation ameliorates exhaustion and prolongs in vivo persistence of chimeric antigen receptor (CAR) expressing T cells

Abstract 4705: Late ALL relapse following CD19 CAR immune-pressure demonstrates reversible pan-antigen loss

Abstract 5598: Engineered hypoimmune allogeneic CAR T cells as potential off-the-shelf CAR T cell immunotherapies

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