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Increased expression of cytochrome P450 2E1 in nonalcoholic fatty liver disease: Mechanisms and pathophysiological role

Clinics and research in hepatology and gastroenterology, 2011-10, Vol.35 (10), p.630-637

2011

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Drug-induced liver injury in obesity and nonalcoholic fatty liver disease

Advances in pharmacology (1990), 2019, Vol.85, p.75-107

2019

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S07-03 Mitochondrial toxicity as a mechanism of xenobiotic-induced steatosis and steatohepatitis

Toxicology letters, 2023-09, Vol.384, p.S27-S28

Fromenty, B.

2023

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Hepatotoxicity in NAFLD: acetaminophen and other xenobiotics

Toxicology letters, 2021-09, Vol.350, p.S56-S57

Fromenty, B.

2021

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Hépatotoxicité des xénobiotiques : principaux mécanismes et modulation par l’obésité

Annales d'endocrinologie, 2014-10, Vol.75 (5), p.248-249

Fromenty, B

2014

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3D multi-cell-type liver organoids: A new model of non-alcoholic fatty liver disease for drug safety assessments

Toxicology in vitro, 2024-02, Vol.94, p.105728-105728, Article 105728

2024

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Burn after feeding. An old uncoupler of oxidative phosphorylation is redesigned for the treatment of nonalcoholic fatty liver disease

Clinics and research in hepatology and gastroenterology, 2014-10, Vol.38 (5), p.545-549

Fromenty, B

2014

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Bridging the gap between old and new concepts in drug-induced liver injury

Clinics and research in hepatology and gastroenterology, 2013-02, Vol.37 (1), p.6-9

Fromenty, B

2013

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Fat accretion in a subpopulation of hepatocytes as a strategy to protect the whole liver against oxidative stress and lipotoxicity

Clinics and research in hepatology and gastroenterology, 2013-12, Vol.37 (6), p.553-555

Fromenty, B

2013

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Maternal and neonatal outcomes and prognostic factors in acute fatty liver of pregnancy

European Journal of Obstetrics & Gynecology and Reproductive Biology, 2020-09, Vol.252, p.198-205

2020

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Roadmap to DILI research in Europe. A proposal from COST action ProEuroDILINet

Pharmacological research, 2024-02, Vol.200, p.107046-107046, Article 107046

2024

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Mitochondria in Steatohepatitis

Seminars in liver disease, 2001, Vol.21 (1), p.057-070

2001

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The ins and outs of mitochondrial dysfunction in NASH

Diabetes & metabolism, 2004-04, Vol.30 (2), p.121-138

2004

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Pentoxifylline aggravates fatty liver in obese and diabetic ob/ob mice by increasing intestinal glucose absorption and activating hepatic lipogenesis

British journal of pharmacology, 2012-03, Vol.165 (5), p.1361-1374

2012

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Benzo[a]pyrene and ethanol exert a high toxicity potential in steatotic HepaRG cells: possible role of low NDUFA4L2 expression

Journal of hepatology, 2017, Vol.66 (1), p.S402-S402

2017

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Drug-induced effects on mtDNA homeostasis in HepaRG cells and modulation by steatosis

Journal of hepatology, 2017, Vol.66 (1), p.S397-S397

2017

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Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity

Pharmacology & therapeutics (Oxford), 1995, Vol.67 (1), p.101-154

1995

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Acute ethanol administration oxidatively damages and depletes mitochondrial dna in mouse liver, brain, heart, and skeletal muscles: protective effects of antioxidants

The Journal of pharmacology and experimental therapeutics, 2001-08, Vol.298 (2), p.737

2001

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Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease

Hepatology (Baltimore, Md.), 2013-10, Vol.58 (4), p.1497-1507

2013

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Indicators of iron status are correlated with adiponectin expression in adipose tissue of patients with morbid obesity

Diabetes & metabolism, 2016-04, Vol.42 (2), p.105-111

2016

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Drug-induced toxicity on mitochondria and lipid metabolism: Mechanistic diversity and deleterious consequences for the liver

Journal of hepatology, 2011-04, Vol.54 (4), p.773-794

2011

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Inhibition of mitochondrial fatty acid oxidation in drug-induced hepatic steatosis

Liver research, 2019-12, Vol.3 (3-4), p.157-169

Fromenty, Bernard

2019

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NASH : a mitochondrial disease

Journal of hepatology, 2005-06, Vol.42 (6), p.928-940

2005

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Steatohepatitis-inducing drugs cause mitochondrial dysfunction and lipid peroxidation in rat hepatocytes

Gastroenterology (New York, N.Y. 1943), 1998-04, Vol.114 (4), p.764-774

1998

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Xenobiotic-Induced Aggravation of Metabolic-Associated Fatty Liver Disease

International journal of molecular sciences, 2022-01, Vol.23 (3), p.1062

2022

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Increased expression of cytochrome P450 2E1 in nonalcoholic fatty liver disease: Mechanisms and pathophysiological role

Drug-induced liver injury in obesity and nonalcoholic fatty liver disease

S07-03 Mitochondrial toxicity as a mechanism of xenobiotic-induced steatosis and steatohepatitis

Hepatotoxicity in NAFLD: acetaminophen and other xenobiotics

Hépatotoxicité des xénobiotiques : principaux mécanismes et modulation par l’obésité

3D multi-cell-type liver organoids: A new model of non-alcoholic fatty liver disease for drug safety assessments

Burn after feeding. An old uncoupler of oxidative phosphorylation is redesigned for the treatment of nonalcoholic fatty liver disease

Bridging the gap between old and new concepts in drug-induced liver injury

Fat accretion in a subpopulation of hepatocytes as a strategy to protect the whole liver against oxidative stress and lipotoxicity

Maternal and neonatal outcomes and prognostic factors in acute fatty liver of pregnancy

Roadmap to DILI research in Europe. A proposal from COST action ProEuroDILINet

Mitochondria in Steatohepatitis

The ins and outs of mitochondrial dysfunction in NASH

Pentoxifylline aggravates fatty liver in obese and diabetic ob/ob mice by increasing intestinal glucose absorption and activating hepatic lipogenesis

Benzo[a]pyrene and ethanol exert a high toxicity potential in steatotic HepaRG cells: possible role of low NDUFA4L2 expression

Drug-induced effects on mtDNA homeostasis in HepaRG cells and modulation by steatosis

Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity

Acute ethanol administration oxidatively damages and depletes mitochondrial dna in mouse liver, brain, heart, and skeletal muscles: protective effects of antioxidants

Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease

Indicators of iron status are correlated with adiponectin expression in adipose tissue of patients with morbid obesity

Drug-induced toxicity on mitochondria and lipid metabolism: Mechanistic diversity and deleterious consequences for the liver

Inhibition of mitochondrial fatty acid oxidation in drug-induced hepatic steatosis

NASH : a mitochondrial disease

Steatohepatitis-inducing drugs cause mitochondrial dysfunction and lipid peroxidation in rat hepatocytes

Xenobiotic-Induced Aggravation of Metabolic-Associated Fatty Liver Disease

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