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Genetic and pharmacological evidence of a role for GABAB receptors in the modulation of anxiety- and antidepressant-like behavior

Neuropsychopharmacology (New York, N.Y.), 2004-06, Vol.29 (6), p.1050-1062

2004

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Chemistry and Pharmacology of GABAB Receptor Ligands

Advances in Pharmacology, 2010, Vol.58, p.19-62

Froestl, Wolfgang

2010

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Repeated administration of the GABAB receptor agonist CGP44532 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine-seeking in rats

Neuropsychopharmacology (New York, N.Y.), 2005-01, Vol.30 (1), p.119-128

2005

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An historical perspective on GABAergic drugs

Future medicinal chemistry, 2011-02, Vol.3 (2), p.163-175

Froestl, Wolfgang

2011

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Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines

The Journal of pharmacology and experimental therapeutics, 2004-09, Vol.310 (3), p.952

2004

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SGS742: the first GABAB receptor antagonist in clinical trials

Biochemical pharmacology, 2004-10, Vol.68 (8), p.1479-1487

2004

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The effects of GABAB agonists and gabapentin on mechanical hyperalgesia in models of neuropathic and inflammatory pain in the rat

Pain (Amsterdam), 2001-02, Vol.90 (3), p.217-226

2001

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Cognitive enhancers (nootropics). Part 1: drugs interacting with receptors

Journal of Alzheimer's disease, 2012-01, Vol.32 (4), p.793-887

2012

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Novel GABA(B) receptor positive modulators: a patent survey

Expert opinion on therapeutic patents, 2010-08, Vol.20 (8), p.1007-1017

Froestl, Wolfgang

2010

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Novel GABAB receptor positive modulators: a patent survey

Expert opinion on therapeutic patents, 2010-08, Vol.20 (8), p.1007-1017

Froestl, Wolfgang

2010

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Human γ -aminobutyric Acid Type B Receptors are Differentially Expressed and Regulate Inwardly Rectifying K+Channels

Proceedings of the National Academy of Sciences - PNAS, 1998-12, Vol.95 (25), p.14991-14996

1998

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The Development of Medications for Alcohol-Use Disorders Targeting the GABAB Receptor System

Recent patents on CNS drug discovery, 2012-08, Vol.7 (2), p.113-128

2012

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Cognitive enhancers (Nootropics). Part 1: drugs interacting with receptors. Update 2014

Journal of Alzheimer's disease, 2014-01, Vol.41 (4), p.961-1019

2014

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Therapeutic intervention in mice deficient for succinate semialdehyde dehydrogenase (gamma-hydroxybutyric aciduria)

The Journal of pharmacology and experimental therapeutics, 2002-07, Vol.302 (1), p.180-187

2002

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Activation of the GABAB Receptor Prevents Nicotine-Induced Locomotor Stimulation in Mice

Frontiers in psychiatry, 2011, Vol.2

2011

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Cognitive enhancers (nootropics). Part 2: drugs interacting with enzymes. Update 2014

Journal of Alzheimer's disease, 2014-01, Vol.42 (1), p.1-68

2014

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Cognitive enhancers (nootropics). Part 3: drugs interacting with targets other than receptors or enzymes. disease-modifying drugs

Journal of Alzheimer's disease, 2013-01, Vol.34 (1), p.1-114

2013

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Cognitive enhancers (nootropics). Part 2: drugs interacting with enzymes

Journal of Alzheimer's disease, 2013-01, Vol.33 (3), p.547-658

2013

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Reducing effect of the positive allosteric modulator of the GABAB receptor, GS39783, on alcohol self-administration in alcohol-preferring rats

Psychopharmacologia, 2007-08, Vol.193 (2), p.171-178

2007

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Novel GABA B receptor positive modulators: a patent survey

Expert opinion on therapeutic patents, 2010-08, Vol.20 (8), p.1007-1017

Froestl, Wolfgang

2010

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Phosphinic Acid Analogs of GABA. 1. New Potent and Selective GABAB Agonists

Journal of medicinal chemistry, 1995-08, Vol.38 (17), p.3297-3312

1995

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Phosphinic Acid Analogs of GABA. 2. Selective, Orally Active GABAB Antagonists

Journal of medicinal chemistry, 1995-08, Vol.38 (17), p.3313-3331

1995

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Cognitive enhancers (Nootropics). Part 3: drugs interacting with targets other than receptors or enzymes. Disease-modifying drugs. Update 2014

Journal of Alzheimer's disease, 2014-01, Vol.42 (4), p.1079-1149

2014

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Genetic and Pharmacological Evidence of a Role for GABA Receptors in the Modulation of Anxiety- and Antidepressant-Like Behavior

Neuropsychopharmacology (New York, N.Y.), 2004-06, Vol.29 (6), p.1050-1062

2004

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The GABAB receptor-positive modulator GS39783 and the GABAB receptor agonist baclofen attenuate the reward-facilitating effects of cocaine : Intracranial self-stimulation studies in the rat

Neuropsychopharmacology (New York, N.Y.), 2005-11, Vol.30 (11), p.2065-2072

2005

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Genetic and pharmacological evidence of a role for GABAB receptors in the modulation of anxiety- and antidepressant-like behavior

Chemistry and Pharmacology of GABAB Receptor Ligands

Repeated administration of the GABAB receptor agonist CGP44532 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine-seeking in rats

An historical perspective on GABAergic drugs

Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines

SGS742: the first GABAB receptor antagonist in clinical trials

The effects of GABAB agonists and gabapentin on mechanical hyperalgesia in models of neuropathic and inflammatory pain in the rat

Cognitive enhancers (nootropics). Part 1: drugs interacting with receptors

Novel GABA(B) receptor positive modulators: a patent survey

Novel GABAB receptor positive modulators: a patent survey

Human γ -aminobutyric Acid Type B Receptors are Differentially Expressed and Regulate Inwardly Rectifying K+Channels

The Development of Medications for Alcohol-Use Disorders Targeting the GABAB Receptor System

Cognitive enhancers (Nootropics). Part 1: drugs interacting with receptors. Update 2014

Therapeutic intervention in mice deficient for succinate semialdehyde dehydrogenase (gamma-hydroxybutyric aciduria)

Activation of the GABAB Receptor Prevents Nicotine-Induced Locomotor Stimulation in Mice

Cognitive enhancers (nootropics). Part 2: drugs interacting with enzymes. Update 2014

Cognitive enhancers (nootropics). Part 3: drugs interacting with targets other than receptors or enzymes. disease-modifying drugs

Cognitive enhancers (nootropics). Part 2: drugs interacting with enzymes

Reducing effect of the positive allosteric modulator of the GABAB receptor, GS39783, on alcohol self-administration in alcohol-preferring rats

Novel GABA B receptor positive modulators: a patent survey

Phosphinic Acid Analogs of GABA. 1. New Potent and Selective GABAB Agonists

Phosphinic Acid Analogs of GABA. 2. Selective, Orally Active GABAB Antagonists

Cognitive enhancers (Nootropics). Part 3: drugs interacting with targets other than receptors or enzymes. Disease-modifying drugs. Update 2014

Genetic and Pharmacological Evidence of a Role for GABA Receptors in the Modulation of Anxiety- and Antidepressant-Like Behavior

The GABAB receptor-positive modulator GS39783 and the GABAB receptor agonist baclofen attenuate the reward-facilitating effects of cocaine : Intracranial self-stimulation studies in the rat

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