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Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases

Nature biotechnology, 2015-02, Vol.33 (2), p.179-186

2015

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Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes

Cell, 2015-11, Vol.163 (4), p.947-959

2015

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PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line

Proceedings of the National Academy of Sciences - PNAS, 2016-09, Vol.113 (38), p.10619-10624

2016

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Genome-wide Translocation Sequencing Reveals Mechanisms of Chromosome Breaks and Rearrangements in B Cells

Cell, 2011-09, Vol.147 (1), p.107-119

2011

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Mechanism of tandem duplication formation in BRCA1-mutant cells

Nature (London), 2017-11, Vol.551 (7682), p.590-595

2017

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Expanding the editable genome and CRISPR-Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking

Nucleic acids research, 2020-01, Vol.48 (2), p.974-995

2020

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Increased AID results in mutations at the CRLF2 locus implicated in Latin American ALL health disparities

Nature communications, 2024-07, Vol.15 (1), p.6331-15, Article 6331

2024

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DNA End Joining: G0-ing to the Core

Biomolecules (Basel, Switzerland), 2021-10, Vol.11 (10), p.1487

2021

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Lamin A/C and emerin are critical for skeletal muscle satellite cell differentiation

Genes & development, 2006-02, Vol.20 (4), p.486-500

2006

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A-Type Lamins Regulate Retinoblastoma Protein Function by Promoting Subnuclear Localization and Preventing Proteasomal Degradation

Proceedings of the National Academy of Sciences - PNAS, 2004-06, Vol.101 (26), p.9677-9682

2004

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Ectopic expression of RAD52 and dn53BP1 improves homology-directed repair during CRISPR-Cas9 genome editing

Nature biomedical engineering, 2017-11, Vol.1 (11), p.878-888

2017

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Parp3 promotes long-range end joining in murine cells

Proceedings of the National Academy of Sciences - PNAS, 2018-10, Vol.115 (40), p.10076-10081

2018

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Detecting DNA double-stranded breaks in mammalian genomes by linear amplification-mediated high-throughput genome-wide translocation sequencing

Nature protocols, 2016-05, Vol.11 (5), p.853-871

2016

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DNA-PKcs suppresses illegitimate chromosome rearrangements

Nucleic acids research, 2024-05, Vol.52 (9), p.5048-5066

2024

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Shifted PAMs generate DNA overhangs and enhance SpCas9 post-catalytic complex dissociation

Nature structural & molecular biology, 2023-11, Vol.30 (11), p.1707-1718

2023

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Author Correction: Shifted PAMs generate DNA overhangs and enhance SpCas9 post-catalytic complex dissociation

Nature structural & molecular biology, 2024-03, Vol.31 (3), p.578-578

2024

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Cardiomyocyte-specific expression of lamin a improves cardiac function in Lmna-/- mice

PloS one, 2012-08, Vol.7 (8), p.e42918-e42918

2012

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Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease

Science translational medicine, 2021-06, Vol.13 (598)

2021

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Precise and broad scope genome editing based on high-specificity Cas9 nickases

Nucleic acids research, 2021-01, Vol.49 (2), p.1173-1198

2021

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Ku70 suppresses alternative end joining in G1-arrested progenitor B cells

Proceedings of the National Academy of Sciences - PNAS, 2021-05, Vol.118 (21), p.1

2021

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Cell-extrinsic defective lymphocyte development in Lmna(-/-) mice

PloS one, 2010-04, Vol.5 (4), p.e10127-e10127

2010

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Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell development

The Journal of experimental medicine, 2016-08, Vol.213 (9), p.1921-1936

2016

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FLASH-RT does not affect chromosome translocations and junction structures beyond that of CONV-RT dose-rates

Radiotherapy and oncology, 2023-11, Vol.188, p.109906-109906, Article 109906

2023

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ATM and 53BP1 regulate alternative end joining–mediated V(D)J recombination

Science advances, 2024-08, Vol.10 (31), p.eadn4682

2024

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Correction: Cardiomyocyte-Specific Expression of Lamin A Improves Cardiac Function in Lmna −/− Mice

PloS one, 2012-09, Vol.7 (9)

2012

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Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases

Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes

PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line

Genome-wide Translocation Sequencing Reveals Mechanisms of Chromosome Breaks and Rearrangements in B Cells

Mechanism of tandem duplication formation in BRCA1-mutant cells

Expanding the editable genome and CRISPR-Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking

Increased AID results in mutations at the CRLF2 locus implicated in Latin American ALL health disparities

DNA End Joining: G0-ing to the Core

Lamin A/C and emerin are critical for skeletal muscle satellite cell differentiation

A-Type Lamins Regulate Retinoblastoma Protein Function by Promoting Subnuclear Localization and Preventing Proteasomal Degradation

Ectopic expression of RAD52 and dn53BP1 improves homology-directed repair during CRISPR-Cas9 genome editing

Parp3 promotes long-range end joining in murine cells

Detecting DNA double-stranded breaks in mammalian genomes by linear amplification-mediated high-throughput genome-wide translocation sequencing

DNA-PKcs suppresses illegitimate chromosome rearrangements

Shifted PAMs generate DNA overhangs and enhance SpCas9 post-catalytic complex dissociation

Author Correction: Shifted PAMs generate DNA overhangs and enhance SpCas9 post-catalytic complex dissociation

Cardiomyocyte-specific expression of lamin a improves cardiac function in Lmna-/- mice

Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease

Precise and broad scope genome editing based on high-specificity Cas9 nickases

Ku70 suppresses alternative end joining in G1-arrested progenitor B cells

Cell-extrinsic defective lymphocyte development in Lmna(-/-) mice

Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell development

FLASH-RT does not affect chromosome translocations and junction structures beyond that of CONV-RT dose-rates

ATM and 53BP1 regulate alternative end joining–mediated V(D)J recombination

Correction: Cardiomyocyte-Specific Expression of Lamin A Improves Cardiac Function in Lmna −/− Mice

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