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Mechanism of Transcription Initiation at an Activator-Dependent Promoter Defined by Single-Molecule Observation

Cell, 2012-02, Vol.148 (4), p.679-689

2012

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Single-molecule studies of origin licensing reveal mechanisms ensuring bidirectional helicase loading

Cell, 2015-04, Vol.161 (3), p.513-525

2015

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A helicase-tethered ORC flip enables bidirectional helicase loading

eLife, 2021-12, Vol.10

2021

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Ordered and Dynamic Assembly of Single Spliceosomes

Science (American Association for the Advancement of Science), 2011-03, Vol.331 (6022), p.1289-1295

2011

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Mechanism and timing of Mcm2-7 ring closure during DNA replication origin licensing

Nature structural & molecular biology, 2017-03, Vol.24 (3), p.309-315

2017

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RNA polymerase approaches its promoter without long-range sliding along DNA

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (24), p.9740-9745

2013

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Dynamics of GreB-RNA polymerase interaction allow a proofreading accessory protein to patrol for transcription complexes needing rescue

Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (7), p.E1081-E1090

2017

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A general mechanism for competitor-induced dissociation of molecular complexes

Nature communications, 2014-10, Vol.5 (1), p.5207-5207, Article 5207

2014

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A conserved Mcm4 motif is required for Mcm2-7 double-hexamer formation and origin DNA unwinding

eLife, 2019-08, Vol.8

2019

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DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7

eLife, 2021-02, Vol.10

2021

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Single-molecule colocalization FRET evidence that spliceosome activation precedes stable approach of 5′ splice site and branch site

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (17), p.6783-6788

2013

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Bayesian machine learning analysis of single-molecule fluorescence colocalization images

eLife, 2022-03, Vol.11

2022

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Alternative Spliceosome Assembly Pathways Revealed by Single-Molecule Fluorescence Microscopy

Cell reports (Cambridge), 2013-10, Vol.5 (1), p.151-165

2013

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Single molecule analysis reveals reversible and irreversible steps during spliceosome activation

eLife, 2016-05, Vol.5

2016

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Synergistic assembly of human pre-spliceosomes across introns and exons

eLife, 2018-06, Vol.7

2018

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The dimerization equilibrium of a ClC Cl(-)/H(+) antiporter in lipid bilayers

eLife, 2016-08, Vol.5

2016

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Design and construction of a multiwavelength, micromirror total internal reflectance fluorescence microscope

Nature protocols, 2014-10, Vol.9 (10), p.2317-2328

2014

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Multi-wavelength single-molecule fluorescence analysis of transcription mechanisms

Methods (San Diego, Calif.), 2015-09, Vol.86, p.27-36

2015

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Single-molecule studies reveal branched pathways for activator-dependent assembly of RNA polymerase II pre-initiation complexes

Molecular cell, 2021-09, Vol.81 (17), p.3576-3588.e6

2021

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Visualizing the splicing of single pre-mRNA molecules in whole cell extract

RNA (Cambridge), 2008-01, Vol.14 (1), p.170-179

2008

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Delayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription

eLife, 2019-02, Vol.8

2019

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RNA polymerase sliding on DNA can couple the transcription of nearby bacterial operons

Proceedings of the National Academy of Sciences - PNAS, 2023-07, Vol.120 (30), p.e2301402120

2023

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Recycling of bacterial RNA polymerase by the Swi2/Snf2 ATPase RapA

Proceedings of the National Academy of Sciences - PNAS, 2023-07, Vol.120 (28), p.e2303849120-e2303849120

2023

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Changing protein-DNA interactions promote ORC binding-site exchange during replication origin licensing

Proceedings of the National Academy of Sciences - PNAS, 2023-07, Vol.120 (30), p.e2305556120-e2305556120

2023

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The Covalent Trimethoprim Chemical Tag Facilitates Single Molecule Imaging with Organic Fluorophores

Biophysical journal, 2014-01, Vol.106 (1), p.272-278

2014

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Mechanism of Transcription Initiation at an Activator-Dependent Promoter Defined by Single-Molecule Observation

Single-molecule studies of origin licensing reveal mechanisms ensuring bidirectional helicase loading

A helicase-tethered ORC flip enables bidirectional helicase loading

Ordered and Dynamic Assembly of Single Spliceosomes

Mechanism and timing of Mcm2-7 ring closure during DNA replication origin licensing

RNA polymerase approaches its promoter without long-range sliding along DNA

Dynamics of GreB-RNA polymerase interaction allow a proofreading accessory protein to patrol for transcription complexes needing rescue

A general mechanism for competitor-induced dissociation of molecular complexes

A conserved Mcm4 motif is required for Mcm2-7 double-hexamer formation and origin DNA unwinding

DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7

Single-molecule colocalization FRET evidence that spliceosome activation precedes stable approach of 5′ splice site and branch site

Bayesian machine learning analysis of single-molecule fluorescence colocalization images

Alternative Spliceosome Assembly Pathways Revealed by Single-Molecule Fluorescence Microscopy

Single molecule analysis reveals reversible and irreversible steps during spliceosome activation

Synergistic assembly of human pre-spliceosomes across introns and exons

The dimerization equilibrium of a ClC Cl(-)/H(+) antiporter in lipid bilayers

Design and construction of a multiwavelength, micromirror total internal reflectance fluorescence microscope

Multi-wavelength single-molecule fluorescence analysis of transcription mechanisms

Single-molecule studies reveal branched pathways for activator-dependent assembly of RNA polymerase II pre-initiation complexes

Visualizing the splicing of single pre-mRNA molecules in whole cell extract

Delayed inhibition mechanism for secondary channel factor regulation of ribosomal RNA transcription

RNA polymerase sliding on DNA can couple the transcription of nearby bacterial operons

Recycling of bacterial RNA polymerase by the Swi2/Snf2 ATPase RapA

Changing protein-DNA interactions promote ORC binding-site exchange during replication origin licensing

The Covalent Trimethoprim Chemical Tag Facilitates Single Molecule Imaging with Organic Fluorophores

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