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Discoidin domain receptor tyrosine kinases: new players in cancer progression

Cancer and metastasis reviews, 2012-06, Vol.31 (1-2), p.295-321

2012

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Discoidin Domain Receptor 1 (DDR1) Is Necessary for Tissue Homeostasis in Pancreatic Injury and Pathogenesis of Pancreatic Ductal Adenocarcinoma

The American journal of pathology, 2020-08, Vol.190 (8), p.1735-1751

2020

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A Highly Specific Inhibitor of Matrix Metalloproteinase-9 Rescues Laminin from Proteolysis and Neurons from Apoptosis in Transient Focal Cerebral Ischemia

The Journal of neuroscience, 2005-07, Vol.25 (27), p.6401-6408

2005

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Increased initiation and growth of tumor cell lines, cancer stem cells and biopsy material in mice using basement membrane matrix protein (Cultrex or Matrigel) co-injection

Nature protocols, 2012-06, Vol.7 (6), p.1138-1144

2012

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Novel MMP-9 Substrates in Cancer Cells Revealed by a Label-free Quantitative Proteomics Approach

Molecular & cellular proteomics, 2008-11, Vol.7 (11), p.2215-2228

2008

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Processing, shedding, and endocytosis of membrane type 1-matrix metalloproteinase (MT1-MMP)

Journal of cellular physiology, 2004-07, Vol.200 (1), p.2-10

2004

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Discoidin domain receptor 1 is a novel transcriptional target of ZEB1 in breast epithelial cells undergoing H‐Ras‐induced epithelial to mesenchymal transition

International journal of cancer, 2015-03, Vol.136 (6), p.E508-E520

2015

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Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein

The EMBO journal, 2006-09, Vol.25 (17), p.3934-3942

2006

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TIMP-2 (tissue inhibitor of metalloproteinase-2) regulates MMP-2 (matrix metalloproteinase-2) activity in the extracellular environment after pro-MMP-2 activation by MT1 (membrane type 1)-MMP

Biochemical journal, 2003-09, Vol.374 (Pt 3), p.739-745

2003

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Preface - Matrix metalloproteinases

Biochimica et biophysica acta. Molecular cell research, 2017-11, Vol.1864 (11 Pt A), p.1925-1926

Fridman, Rafael

2017

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Expression and subcellular localization of Discoidin Domain Receptor 1 (DDR1) define prostate cancer aggressiveness

Cancer cell international, 2021-09, Vol.21 (1), p.1-507, Article 507

2021

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Galectin-3 Cleavage : A Novel Surrogate Marker for Matrix Metalloproteinase Activity in Growing Breast Cancers

Cancer research (Chicago, Ill.), 2007-12, Vol.67 (24), p.11760-11768

2007

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Discoidin domain receptor 1 activation links extracellular matrix to podocyte lipotoxicity in Alport syndrome

EBioMedicine, 2021-01, Vol.63, p.103162, Article 103162

2021

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Angiotensin‐converting enzyme inhibitors increase anti‐fibrotic biomarkers in African Americans with left ventricular hypertrophy

The journal of clinical hypertension (Greenwich, Conn.), 2021-05, Vol.23 (5), p.1008-1016

2021

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Shedding of RANKL by Tumor-Associated MT1-MMP Activates Src-Dependent Prostate Cancer Cell Migration

Cancer research (Chicago, Ill.), 2010-07, Vol.70 (13), p.5558-5566

2010

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New Concepts on the Interactions of Discoidin Domain Receptors with Collagen

Biochimica et biophysica acta. Molecular cell research, 2019-11, Vol.1866 (11), p.118527-118527, Article 118527

2019

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Selective pharmacological inhibition of DDR1 prevents experimentally-induced glomerulonephritis in prevention and therapeutic regime

Journal of translational medicine, 2018-06, Vol.16 (1), p.148-20, Article 148

2018

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Glycosylation at Asn211 Regulates the Activation State of the Discoidin Domain Receptor 1 (DDR1)

The Journal of biological chemistry, 2014-03, Vol.289 (13), p.9275-9287

2014

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TIMP-1 induces an EMT-like phenotypic conversion in MDCK cells independent of its MMP-inhibitory domain

PloS one, 2012-06, Vol.7 (6), p.e38773-e38773

2012

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Discoidin Domain Receptors in Melanoma: Potential Therapeutic Targets to Overcome MAPK Inhibitor Resistance

Frontiers in oncology, 2020-09, Vol.10, p.1748-1748

2020

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Pro-MMP-9 activation by the MT1-MMP/MMP-2 axis and MMP-3: role of TIMP-2 and plasma membranes

Biochemical and biophysical research communications, 2003-08, Vol.308 (2), p.386-395

2003

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Characterization of the Dimerization Interface of Membrane Type 4 (MT4)-Matrix Metalloproteinase

The Journal of biological chemistry, 2011-09, Vol.286 (38), p.33178-33189

2011

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Potent Mechanism-based Inhibitors for Matrix Metalloproteinases

The Journal of biological chemistry, 2005-10, Vol.280 (40), p.33992-34002

2005

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Increased Expression of Matrix Metalloproteinases (MMP)-2, MMP-9, and the Urokinase-Type Plasminogen Activator Is Associated with Progression from Benign to Advanced Ovarian Cancer

Clinical cancer research, 2001-08, Vol.7 (8), p.2396-2404

2001

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Discoidin domain receptor tyrosine kinases: new players in cancer progression

Discoidin Domain Receptor 1 (DDR1) Is Necessary for Tissue Homeostasis in Pancreatic Injury and Pathogenesis of Pancreatic Ductal Adenocarcinoma

DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome

A Highly Specific Inhibitor of Matrix Metalloproteinase-9 Rescues Laminin from Proteolysis and Neurons from Apoptosis in Transient Focal Cerebral Ischemia

Increased initiation and growth of tumor cell lines, cancer stem cells and biopsy material in mice using basement membrane matrix protein (Cultrex or Matrigel) co-injection

Novel MMP-9 Substrates in Cancer Cells Revealed by a Label-free Quantitative Proteomics Approach

Processing, shedding, and endocytosis of membrane type 1-matrix metalloproteinase (MT1-MMP)

Discoidin domain receptor 1 is a novel transcriptional target of ZEB1 in breast epithelial cells undergoing H‐Ras‐induced epithelial to mesenchymal transition

Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein

TIMP-2 (tissue inhibitor of metalloproteinase-2) regulates MMP-2 (matrix metalloproteinase-2) activity in the extracellular environment after pro-MMP-2 activation by MT1 (membrane type 1)-MMP

Preface - Matrix metalloproteinases

Expression and subcellular localization of Discoidin Domain Receptor 1 (DDR1) define prostate cancer aggressiveness

Galectin-3 Cleavage : A Novel Surrogate Marker for Matrix Metalloproteinase Activity in Growing Breast Cancers

Discoidin domain receptor 1 activation links extracellular matrix to podocyte lipotoxicity in Alport syndrome

Angiotensin‐converting enzyme inhibitors increase anti‐fibrotic biomarkers in African Americans with left ventricular hypertrophy

Shedding of RANKL by Tumor-Associated MT1-MMP Activates Src-Dependent Prostate Cancer Cell Migration

New Concepts on the Interactions of Discoidin Domain Receptors with Collagen

Selective pharmacological inhibition of DDR1 prevents experimentally-induced glomerulonephritis in prevention and therapeutic regime

Glycosylation at Asn211 Regulates the Activation State of the Discoidin Domain Receptor 1 (DDR1)

TIMP-1 induces an EMT-like phenotypic conversion in MDCK cells independent of its MMP-inhibitory domain

Discoidin Domain Receptors in Melanoma: Potential Therapeutic Targets to Overcome MAPK Inhibitor Resistance

Pro-MMP-9 activation by the MT1-MMP/MMP-2 axis and MMP-3: role of TIMP-2 and plasma membranes

Characterization of the Dimerization Interface of Membrane Type 4 (MT4)-Matrix Metalloproteinase

Potent Mechanism-based Inhibitors for Matrix Metalloproteinases

Increased Expression of Matrix Metalloproteinases (MMP)-2, MMP-9, and the Urokinase-Type Plasminogen Activator Is Associated with Progression from Benign to Advanced Ovarian Cancer

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