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Small molecule induced STING degradation facilitated by the HECT ligase HERC4

Nature communications, 2024-05, Vol.15 (1), p.4584-16, Article 4584

2024

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Discovery of a selective and biologically active low-molecular weight antagonist of human interleukin-1β

Nature communications, 2023-09, Vol.14 (1), p.5497-5497, Article 5497

2023

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Two Antagonistic MALT1 Auto-Cleavage Mechanisms Reveal a Role for TRAF6 to Unleash MALT1 Activation

PloS one, 2017-01, Vol.12 (1), p.e0169026-e0169026

2017

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X‐ray Structures and Feasibility Assessment of CLK2 Inhibitors for Phelan–McDermid Syndrome

ChemMedChem, 2018-09, Vol.13 (18), p.1997-2007

2018

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High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor

PloS one, 2016-09, Vol.11 (9), p.e0163129

2016

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Reversible translocation of p115-RhoGEF by G12/13-coupled receptors

Journal of cellular biochemistry, 2008-08, Vol.104 (5), p.1660-1670

2008

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Identification of cardiac glycoside molecules as inhibitors of c-Myc IRES-mediated translation

Journal of biomolecular screening, 2013-04, Vol.18 (4), p.407-419

2013

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Serum Amyloid A (apoSAA) Expression Is Up-Regulated in Rheumatoid Arthritis and Induces Transcription of Matrix Metalloproteinases

The Journal of immunology (1950), 2001-02, Vol.166 (4), p.2801-2807

2001

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Development of a novel Gateway-based vector system for efficient, multiparallel protein expression in Escherichia coli

Protein expression and purification, 2008-06, Vol.59 (2), p.232-241

2008

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Structural basis of species-selective antagonist binding to the succinate receptor

Nature (London), 2019-10, Vol.574 (7779), p.581-585

2019

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The structure of Ca2+ sensor Case16 reveals the mechanism of reaction to low Ca2+ concentrations

Sensors (Basel, Switzerland), 2010-09, Vol.10 (9), p.8143-8160

2010

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Structural Determinants of MALT1 Protease Activity

Journal of molecular biology, 2012-05, Vol.419 (1-2), p.4-21

2012

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Gift from Nature: Cyclomarin A Kills Mycobacteria and Malaria Parasites by Distinct Modes of Action

Chembiochem : a European journal of chemical biology, 2015-11, Vol.16 (17), p.2433-2436

2015

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Muscle Nicotinic Acetylcholine Receptors containing α1‐V275 or α1‐Y233 Mutants found in a functional Screen reveal enhanced Agonist Potencies

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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Reversible translocation of p115-RhoGEF by G(12/13)-coupled receptors

Journal of cellular biochemistry, 2008-08, Vol.104 (5), p.1660-1670

2008

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Evaluation of two novel tag-based labelling technologies for site-specific modification of proteins

International journal of biological macromolecules, 2006-08, Vol.39 (1), p.66-76

2006

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Inside Cover: Gift from Nature: CyclomarinA Kills Mycobacteria and Malaria Parasites by Distinct Modes of Action

Chembiochem : a European journal of chemical biology, 2015-11, Vol.16 (17), p.2406

2015

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Gift from Nature: CyclomarinA Kills Mycobacteria and Malaria Parasites by Distinct Modes of Action

Chembiochem : a European journal of chemical biology, 2015-11, Vol.16 (17), p.2433-2436

2015

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Inside Cover: Gift from Nature: Cyclomarin A Kills Mycobacteria and Malaria Parasites by Distinct Modes of Action (ChemBioChem 17/2015)

Chembiochem : a European journal of chemical biology, 2015-11, Vol.16 (17), p.2406-2406

2015

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Novel pharmacological insights for adenylyl cyclase 5, a gatekeeper of GPCR signaling

The FASEB journal, 2010-04, Vol.24 (S1), p.lb477-lb477

2010

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HDL-like discs for assaying membrane proteins in drug discovery

Biophysical chemistry, 2012-05, Vol.165-166, p.56-61

2012

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Reversible translocation of p115‐RhoGEF by G 12/13 ‐coupled receptors

Journal of cellular biochemistry, 2008-08, Vol.104 (5), p.1660-1670

2008

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Synthesis and characterization of fluorescent ubiquitin derivatives as highly sensitive substrates for the deubiquitinating enzymes UCH-L3 and USP-2

Analytical biochemistry, 2005-08, Vol.343 (2), p.244-255

2005

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Rapid Identification of Phosphopeptide Ligands for SH2 Domains

The Journal of biological chemistry, 1996-07, Vol.271 (28), p.16500-16505

1996

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Small molecule induced STING degradation facilitated by the HECT ligase HERC4

Discovery of a selective and biologically active low-molecular weight antagonist of human interleukin-1β

Two Antagonistic MALT1 Auto-Cleavage Mechanisms Reveal a Role for TRAF6 to Unleash MALT1 Activation

X‐ray Structures and Feasibility Assessment of CLK2 Inhibitors for Phelan–McDermid Syndrome

High Throughput Random Mutagenesis and Single Molecule Real Time Sequencing of the Muscle Nicotinic Acetylcholine Receptor

Reversible translocation of p115-RhoGEF by G12/13-coupled receptors

Identification of cardiac glycoside molecules as inhibitors of c-Myc IRES-mediated translation

Serum Amyloid A (apoSAA) Expression Is Up-Regulated in Rheumatoid Arthritis and Induces Transcription of Matrix Metalloproteinases

Development of a novel Gateway-based vector system for efficient, multiparallel protein expression in Escherichia coli

Structural basis of species-selective antagonist binding to the succinate receptor

The structure of Ca2+ sensor Case16 reveals the mechanism of reaction to low Ca2+ concentrations

PAX8 and MECOM are interaction partners driving ovarian cancer

Structural Determinants of MALT1 Protease Activity

Gift from Nature: Cyclomarin A Kills Mycobacteria and Malaria Parasites by Distinct Modes of Action

Muscle Nicotinic Acetylcholine Receptors containing α1‐V275 or α1‐Y233 Mutants found in a functional Screen reveal enhanced Agonist Potencies

Reversible translocation of p115-RhoGEF by G(12/13)-coupled receptors

Evaluation of two novel tag-based labelling technologies for site-specific modification of proteins

Inside Cover: Gift from Nature: CyclomarinA Kills Mycobacteria and Malaria Parasites by Distinct Modes of Action

Gift from Nature: CyclomarinA Kills Mycobacteria and Malaria Parasites by Distinct Modes of Action

Inside Cover: Gift from Nature: Cyclomarin A Kills Mycobacteria and Malaria Parasites by Distinct Modes of Action (ChemBioChem 17/2015)

Novel pharmacological insights for adenylyl cyclase 5, a gatekeeper of GPCR signaling

HDL-like discs for assaying membrane proteins in drug discovery

Reversible translocation of p115‐RhoGEF by G 12/13 ‐coupled receptors

Synthesis and characterization of fluorescent ubiquitin derivatives as highly sensitive substrates for the deubiquitinating enzymes UCH-L3 and USP-2

Rapid Identification of Phosphopeptide Ligands for SH2 Domains

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