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Dual Role of the PTPN13 Tyrosine Phosphatase in Cancer

Biomolecules (Basel, Switzerland), 2020-12, Vol.10 (12), p.1659

2020

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PTPN13 Participates in the Regulation of Epithelial–Mesenchymal Transition and Platinum Sensitivity in High-Grade Serous Ovarian Carcinoma Cells

International journal of molecular sciences, 2023-10, Vol.24 (20), p.15413

2023

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PTPN13/PTPL1: an important regulator of tumor aggressiveness

Anti-cancer agents in medicinal chemistry, 2011-01, Vol.11 (1), p.78

2011

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Network Reconstruction and Significant Pathway Extraction Using Phosphoproteomic Data from Cancer Cells

Proteomics (Weinheim), 2019-11, Vol.19 (21-22), p.e1800450-n/a

2019

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Comparison of SYK Signaling Networks Reveals the Potential Molecular Determinants of Its Tumor-Promoting and Suppressing Functions

Biomolecules (Basel, Switzerland), 2021-02, Vol.11 (2), p.308

2021

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The putative tumor suppressor gene PTPN13/PTPL1 induces apoptosis through insulin receptor substrate-1 dephosphorylation

Cancer research (Chicago, Ill.), 2007-07, Vol.67 (14), p.6806-6813

2007

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Involvement of Rac in actin cytoskeleton rearrangements induced by MIM-B

Journal of cell science, 2005-11, Vol.118 (22), p.5393-5403

2005

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Reconstruction and signal propagation analysis of the Syk signaling network in breast cancer cells

PLoS computational biology, 2017-03, Vol.13 (3), p.e1005432-e1005432

2017

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PTPN13 induces cell junction stabilization and inhibits mammary tumor invasiveness

Theranostics, 2020-01, Vol.10 (3), p.1016-1032

2020

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The Syk Kinase Promotes Mammary Epithelial Integrity and Inhibits Breast Cancer Invasion by Stabilizing the E-Cadherin/Catenin Complex

Cancers, 2019-12, Vol.11 (12), p.1974

2019

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Protein-tyrosine Phosphatase PTPL1/FAP-1 Triggers Apoptosis in Human Breast Cancer Cells

The Journal of biological chemistry, 2002-12, Vol.277 (49), p.47861-47869

2002

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Protein tyrosine phosphatases and breast cancer

Critical reviews in oncology/hematology, 2004-10, Vol.52 (1), p.9-17

2004

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Membrane targeting of protein tyrosine phosphatase PTPL1 through its FERM domain via binding to phosphatidylinositol 4,5-biphosphate

Journal of cell science, 2003-06, Vol.116 (Pt 12), p.2519-2530

2003

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High PTPN13 expression in high grade serous ovarian carcinoma is associated with a better patient outcome

Oncotarget, 2017-11, Vol.8 (56), p.95662-95673

2017

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PTPL1/PTPN13 Regulates Breast Cancer Cell Aggressiveness through Direct Inactivation of Src Kinase

Cancer research (Chicago, Ill.), 2010-06, Vol.70 (12), p.5116-5126

2010

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PTPL1, a proapoptotic protein tyrosine phosphatase in breast cancers

Bulletin du cancer, 2004-04, Vol.91 (4), p.325

2004

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Expression of the putative tumor suppressor gene PTPN13/PTPL1 is an independent prognostic marker for overall survival in breast cancer

International journal of cancer, 2009-02, Vol.124 (3), p.638-643

2009

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Catalytically Inactive Human Cathepsin D Triggers Fibroblast Invasive Growth

The Journal of cell biology, 2005-01, Vol.168 (3), p.489-499

2005

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Estrogen-induced lysosomal proteases secreted by breast cancer cells: A role in carcinogenesis?

Journal of cellular biochemistry, 1987-09, Vol.35 (1), p.17-29

1987

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Abstract 4704: Effects of the HDAC inhibitor S78454/PCI-24781 on ER signalling in ERα-positive antiestrogen-sensitive and -resistant breast cancer cells

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.4704-4704

2012

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Downregulation of protein tyrosine phosphatase PTP-BL represses adipogenesis

The international journal of biochemistry & cell biology, 2009-11, Vol.41 (11), p.2173-2180

2009

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PTPL1/PTPN13 regulates breast cancer cell aggressiveness through direct inactivation of Src kinase: PTPL1 inhibits Src activation and tumor aggressiveness

Cancer research (Chicago, Ill.), 2010-06, Vol.70 (12), p.5116-26

2010

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Downregulation of protein tyrosine phosphatase PTP-BL represses adipogenesis

The international journal of biochemistry & cell biology, 2009-11, Vol.41 (11), p.2173-80

2009

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Extinction of Insulin-Like Growth Factor-I Mitogenic Signaling by Antiestrogen-Stimulated Fas-Associated Protein Tyrosine Phosphatase-1 in Human Breast Cancer Cells

Molecular endocrinology (Baltimore, Md.), 1998-04, Vol.12 (4), p.568-579

1998

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Structure, function, regulation and clinical significance of the 52K pro-cathepsin D secreted by breast cancer cells

Biochimie, 1988-07, Vol.70 (7), p.943-949

1988

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Dual Role of the PTPN13 Tyrosine Phosphatase in Cancer

PTPN13 Participates in the Regulation of Epithelial–Mesenchymal Transition and Platinum Sensitivity in High-Grade Serous Ovarian Carcinoma Cells

PTPN13/PTPL1: an important regulator of tumor aggressiveness

Network Reconstruction and Significant Pathway Extraction Using Phosphoproteomic Data from Cancer Cells

Comparison of SYK Signaling Networks Reveals the Potential Molecular Determinants of Its Tumor-Promoting and Suppressing Functions

The putative tumor suppressor gene PTPN13/PTPL1 induces apoptosis through insulin receptor substrate-1 dephosphorylation

Involvement of Rac in actin cytoskeleton rearrangements induced by MIM-B

Reconstruction and signal propagation analysis of the Syk signaling network in breast cancer cells

PTPN13 induces cell junction stabilization and inhibits mammary tumor invasiveness

The Syk Kinase Promotes Mammary Epithelial Integrity and Inhibits Breast Cancer Invasion by Stabilizing the E-Cadherin/Catenin Complex

Protein-tyrosine Phosphatase PTPL1/FAP-1 Triggers Apoptosis in Human Breast Cancer Cells

Protein tyrosine phosphatases and breast cancer

Membrane targeting of protein tyrosine phosphatase PTPL1 through its FERM domain via binding to phosphatidylinositol 4,5-biphosphate

High PTPN13 expression in high grade serous ovarian carcinoma is associated with a better patient outcome

PTPL1/PTPN13 Regulates Breast Cancer Cell Aggressiveness through Direct Inactivation of Src Kinase

PTPL1, a proapoptotic protein tyrosine phosphatase in breast cancers

Expression of the putative tumor suppressor gene PTPN13/PTPL1 is an independent prognostic marker for overall survival in breast cancer

Catalytically Inactive Human Cathepsin D Triggers Fibroblast Invasive Growth

Estrogen-induced lysosomal proteases secreted by breast cancer cells: A role in carcinogenesis?

Abstract 4704: Effects of the HDAC inhibitor S78454/PCI-24781 on ER signalling in ERα-positive antiestrogen-sensitive and -resistant breast cancer cells

Downregulation of protein tyrosine phosphatase PTP-BL represses adipogenesis

PTPL1/PTPN13 regulates breast cancer cell aggressiveness through direct inactivation of Src kinase: PTPL1 inhibits Src activation and tumor aggressiveness

Downregulation of protein tyrosine phosphatase PTP-BL represses adipogenesis

Extinction of Insulin-Like Growth Factor-I Mitogenic Signaling by Antiestrogen-Stimulated Fas-Associated Protein Tyrosine Phosphatase-1 in Human Breast Cancer Cells

Structure, function, regulation and clinical significance of the 52K pro-cathepsin D secreted by breast cancer cells

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