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Dietary medium chain fatty acid supplementation leads to reduced VLDL lipolysis and uptake rates in comparison to linoleic acid supplementation

PloS one, 2014-07, Vol.9 (7), p.e100376-e100376

2014

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Nutritional systems biology modeling: from molecular mechanisms to physiology

PLoS computational biology, 2009-11, Vol.5 (11), p.e1000554-e1000554

2009

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Quantitative profiling of bile acids in biofluids and tissues based on accurate mass high resolution LC-FT-MS: Compound class targeting in a metabolomics workflow

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008-08, Vol.871 (2), p.306-313

2008

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Association between Consumption of Cruciferous Vegetables and Condiments and Excretion in Urine of Isothiocyanate Mercapturic Acids

Journal of agricultural and food chemistry, 2006-07, Vol.54 (15), p.5350-5358

2006

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A physiologically based biokinetic (PBBK) model for estragole bioactivation and detoxification in rat

Toxicology and applied pharmacology, 2008-09, Vol.231 (2), p.248-259

2008

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Use of Physiologically Based Biokinetic (PBBK) Modeling to Study Estragole Bioactivation and Detoxification in Humans as Compared with Male Rats

Toxicological sciences, 2009-08, Vol.110 (2), p.255-269

2009

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Predicted Serum Folate Concentrations Based on In Vitro Studies and Kinetic Modeling are Consistent with Measured Folate Concentrations in Humans

The Journal of nutrition, 2006-12, Vol.136 (12), p.3074-3078

2006

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Prediction of in vivo embryotoxic effect levels with a combination of in vitro studies and PBPK modelling

Toxicology letters, 2006-08, Vol.165 (1), p.79-87

2006

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New in vitro dermal absorption database and the prediction of dermal absorption under finite conditions for risk assessment purposes

Regulatory toxicology and pharmacology, 2010-07, Vol.57 (2-3), p.200-209

2010

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Improved cholesterol phenotype analysis by a model relating lipoprotein life cycle processes to particle size[S]

Journal of lipid research, 2009-12, Vol.50 (12), p.2398-2411

2009

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Diagnostic markers based on a computational model of lipoprotein metabolism

Journal of clinical bioinformatics, 2011-10, Vol.1 (1), p.29-29

2011

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An in vitro and in silico study on the flavonoid-mediated modulation of the transport of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) through Caco-2 monolayers

Toxicology and applied pharmacology, 2006-12, Vol.217 (2), p.204-215

2006

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Modeling the in vitro intrinsic clearance of the slowly metabolized compound tolbutamide determined in sandwich-cultured rat hepatocytes

Drug metabolism and disposition, 2004-08, Vol.32 (8), p.884-891

2004

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Systematic construction of a conceptual minimal model of plasma cholesterol levels based on knockout mouse phenotypes

Biochimica et biophysica acta, 2010-06, Vol.1801 (6), p.646-654

2010

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Transcriptomics analysis of interactive effects of benzene, trichloroethylene and methyl mercury within binary and ternary mixtures on the liver and kidney following subchronic exposure in the rat

Toxicology and applied pharmacology, 2007-12, Vol.225 (2), p.171-188

2007

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Influence of pH and Other Modifying Factors on the Distribution Behavior of 4-Quinolones to Solid Phases and Humic Acids Studied by “Negligible-Depletion” SPME−HPLC

Environmental science & technology, 2000-12, Vol.34 (23), p.4989-4994

2000

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Developing computational model-based diagnostics to analyse clinical chemistry data

Briefings in bioinformatics, 2010-07, Vol.11 (4), p.403-416

2010

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Quercetin increases the bioavailability of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) in rats

Food and chemical toxicology, 2008-11, Vol.46 (11), p.3422-3428

2008

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Estimating impact of humic acid on bioavailability and bioaccumulation of hydrophobic chemicals in guppies using kinetic solid-phase extraction

Environmental toxicology and chemistry, 1998-06, Vol.17 (6), p.998-1004

1998

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Comparing the Potency of Chemicals with Multiple Modes of Action in Aquatic Toxicology: Acute Toxicity Due to Narcosis versus Reactive Toxicity of Acrylic Compounds

Environmental science & technology, 1999-09, Vol.33 (17), p.3038-3043

1999

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Toxicology of chemical mixtures: a challenging quest along empirical sciences

Environmental toxicology and pharmacology, 2004-12, Vol.18 (3), p.185-192

2004

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Quantitative structure-property relationships for the chemical reactivity of acrylates and methacrylates

Environmental toxicology and chemistry, 1999-06, Vol.18 (6), p.1133-1139

1999

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Hexabody-CD38, a Novel CD38 Antibody with a Hexamerization Enhancing Mutation, Demonstrates Enhanced Complement-Dependent Cytotoxicity and Shows Potent Anti-Tumor Activity in Preclinical Models of Hematological Malignancies

Blood, 2019-11, Vol.134 (Supplement_1), p.3106-3106

2019

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Prediction of isoprene diepoxide levels in vivo in mouse, rat and man using enzyme kinetic data in vitro and physiologically-based pharmacokinetic modelling

Chemico-biological interactions, 2001-12, Vol.138 (3), p.247-265

2001

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Review of the clinical development of alipogene tiparvovec gene therapy for lipoprotein lipase deficiency

Atherosclerosis. Supplement (Amsterdam), 2010-06, Vol.11 (1), p.55-60

2010

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Dietary medium chain fatty acid supplementation leads to reduced VLDL lipolysis and uptake rates in comparison to linoleic acid supplementation

Nutritional systems biology modeling: from molecular mechanisms to physiology

Quantitative profiling of bile acids in biofluids and tissues based on accurate mass high resolution LC-FT-MS: Compound class targeting in a metabolomics workflow

Association between Consumption of Cruciferous Vegetables and Condiments and Excretion in Urine of Isothiocyanate Mercapturic Acids

A physiologically based biokinetic (PBBK) model for estragole bioactivation and detoxification in rat

Use of Physiologically Based Biokinetic (PBBK) Modeling to Study Estragole Bioactivation and Detoxification in Humans as Compared with Male Rats

Predicted Serum Folate Concentrations Based on In Vitro Studies and Kinetic Modeling are Consistent with Measured Folate Concentrations in Humans

Prediction of in vivo embryotoxic effect levels with a combination of in vitro studies and PBPK modelling

New in vitro dermal absorption database and the prediction of dermal absorption under finite conditions for risk assessment purposes

Improved cholesterol phenotype analysis by a model relating lipoprotein life cycle processes to particle size[S]

Diagnostic markers based on a computational model of lipoprotein metabolism

An in vitro and in silico study on the flavonoid-mediated modulation of the transport of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) through Caco-2 monolayers

Modeling the in vitro intrinsic clearance of the slowly metabolized compound tolbutamide determined in sandwich-cultured rat hepatocytes

Systematic construction of a conceptual minimal model of plasma cholesterol levels based on knockout mouse phenotypes

Transcriptomics analysis of interactive effects of benzene, trichloroethylene and methyl mercury within binary and ternary mixtures on the liver and kidney following subchronic exposure in the rat

Influence of pH and Other Modifying Factors on the Distribution Behavior of 4-Quinolones to Solid Phases and Humic Acids Studied by “Negligible-Depletion” SPME−HPLC

Developing computational model-based diagnostics to analyse clinical chemistry data

Quercetin increases the bioavailability of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) in rats

Estimating impact of humic acid on bioavailability and bioaccumulation of hydrophobic chemicals in guppies using kinetic solid-phase extraction

Comparing the Potency of Chemicals with Multiple Modes of Action in Aquatic Toxicology: Acute Toxicity Due to Narcosis versus Reactive Toxicity of Acrylic Compounds

Toxicology of chemical mixtures: a challenging quest along empirical sciences

Quantitative structure-property relationships for the chemical reactivity of acrylates and methacrylates

Hexabody-CD38, a Novel CD38 Antibody with a Hexamerization Enhancing Mutation, Demonstrates Enhanced Complement-Dependent Cytotoxicity and Shows Potent Anti-Tumor Activity in Preclinical Models of Hematological Malignancies

Prediction of isoprene diepoxide levels in vivo in mouse, rat and man using enzyme kinetic data in vitro and physiologically-based pharmacokinetic modelling

Review of the clinical development of alipogene tiparvovec gene therapy for lipoprotein lipase deficiency

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