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Formation and Signaling Actions of Electrophilic Lipids

Chemical reviews, 2011-10, Vol.111 (10), p.5997-6021

2011

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Enterosalivary nitrate metabolism and the microbiome: Intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health

Free radical biology & medicine, 2017-04, Vol.105, p.48-67

2017

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Transduction of redox signaling by electrophile-protein reactions

Science signaling, 2009-09, Vol.2 (90), p.re7

2009

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Redox-dependent anti-inflammatory signaling actions of unsaturated fatty acids

Annual review of physiology, 2014-01, Vol.76 (1), p.79-105

2014

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Nitro-fatty acids: New drug candidates for chronic inflammatory and fibrotic diseases

Nitric oxide, 2018-09, Vol.79, p.31-37

2018

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Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase

Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (22), p.8167-8172

2014

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Olives and olive oil are sources of electrophilic fatty acid nitroalkenes

PloS one, 2014-01, Vol.9 (1), p.e84884-e84884

2014

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Redox signaling in inflammation: interactions of endogenous electrophiles and mitochondria in cardiovascular disease

Annals of the New York Academy of Sciences, 2010-08, Vol.1203 (1), p.45-52

2010

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Electrophilic Nitro-fatty Acids Activate NRF2 by a KEAP1 Cysteine 151-independent Mechanism

The Journal of biological chemistry, 2011-04, Vol.286 (16), p.14019-14027

2011

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Electrophilic fatty acid nitroalkenes are systemically transported and distributed upon esterification to complex lipids[S]

Journal of lipid research, 2019-02, Vol.60 (2), p.388-399

2019

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Electrophilic nitro-fatty acids inhibit vascular inflammation by disrupting LPS-dependent TLR4 signalling in lipid rafts

Cardiovascular research, 2013-04, Vol.98 (1), p.116-124

2013

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Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples

Nature communications, 2023-11, Vol.14 (1), p.7172-7172, Article 7172

2023

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Electrophilic characteristics and aqueous behavior of fatty acid nitroalkenes

Redox biology, 2021-01, Vol.38, p.101756-101756, Article 101756

2021

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Febuxostat inhibition of endothelial-bound XO: Implications for targeting vascular ROS production

Free radical biology & medicine, 2011-07, Vol.51 (1), p.179-184

2011

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Conjugated Linoleic Acid Is a Preferential Substrate for Fatty Acid Nitration

The Journal of biological chemistry, 2012-12, Vol.287 (53), p.44071-44082

2012

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Convergence of biological nitration and nitrosation via symmetrical nitrous anhydride

Nature chemical biology, 2015-07, Vol.11 (7), p.504

2015

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Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusion

Cardiovascular research, 2010-01, Vol.85 (1), p.155-166

2010

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Generation and dietary modulation of anti-inflammatory electrophilic omega-3 fatty acid derivatives

PloS one, 2014-04, Vol.9 (4), p.e94836

2014

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Synaptic Zn2+ inhibits neurotransmitter release by promoting endocannabinoid synthesis

The Journal of neuroscience, 2013-05, Vol.33 (22), p.9259-9272

2013

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Nitro-oleic acid, a ligand of CD36, reduces cholesterol accumulation by modulating oxidized-LDL uptake and cholesterol efflux in RAW264.7 macrophages

Redox biology, 2020-09, Vol.36, p.101591-101591, Article 101591

2020

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Nitroalkene fatty acids modulate bile acid metabolism and lung function in obese asthma

Scientific reports, 2021-09, Vol.11 (1), p.17788-17788, Article 17788

2021

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Nitrated Fatty Acids: Endogenous Anti-inflammatory Signaling Mediators

The Journal of biological chemistry, 2006-11, Vol.281 (47), p.35686-35698

2006

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Reversible Post-translational Modification of Proteins by Nitrated Fatty Acids in Vivo

The Journal of biological chemistry, 2006-07, Vol.281 (29), p.20450-20463

2006

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Fatty acid nitroalkenes – Multi-target agents for the treatment of sickle cell disease

Redox biology, 2023-12, Vol.68, p.102941-102941, Article 102941

2023

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Formation and Signaling Actions of Electrophilic Lipids

Enterosalivary nitrate metabolism and the microbiome: Intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health

Transduction of redox signaling by electrophile-protein reactions

Redox-dependent anti-inflammatory signaling actions of unsaturated fatty acids

Nitro-fatty acids: New drug candidates for chronic inflammatory and fibrotic diseases

Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase

Olives and olive oil are sources of electrophilic fatty acid nitroalkenes

Redox signaling in inflammation: interactions of endogenous electrophiles and mitochondria in cardiovascular disease

Electrophilic Nitro-fatty Acids Activate NRF2 by a KEAP1 Cysteine 151-independent Mechanism

Electrophilic fatty acid nitroalkenes are systemically transported and distributed upon esterification to complex lipids[S]

Electrophilic nitro-fatty acids inhibit vascular inflammation by disrupting LPS-dependent TLR4 signalling in lipid rafts

Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples

Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation

Electrophilic characteristics and aqueous behavior of fatty acid nitroalkenes

Febuxostat inhibition of endothelial-bound XO: Implications for targeting vascular ROS production

Conjugated Linoleic Acid Is a Preferential Substrate for Fatty Acid Nitration

Convergence of biological nitration and nitrosation via symmetrical nitrous anhydride

Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusion

Generation and dietary modulation of anti-inflammatory electrophilic omega-3 fatty acid derivatives

Synaptic Zn2+ inhibits neurotransmitter release by promoting endocannabinoid synthesis

Nitro-oleic acid, a ligand of CD36, reduces cholesterol accumulation by modulating oxidized-LDL uptake and cholesterol efflux in RAW264.7 macrophages

Nitroalkene fatty acids modulate bile acid metabolism and lung function in obese asthma

Nitrated Fatty Acids: Endogenous Anti-inflammatory Signaling Mediators

Reversible Post-translational Modification of Proteins by Nitrated Fatty Acids in Vivo

Fatty acid nitroalkenes – Multi-target agents for the treatment of sickle cell disease

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