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The Impact of Preclinical Irreproducibility on Drug Development

Clinical pharmacology and therapeutics, 2015-01, Vol.97 (1), p.16-18

2015

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Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex

Nature (London), 1999-04, Vol.398 (6730), p.824-828

1999

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Human rights, constructive accountability and maternal mortality in the Dominican Republic: a commentary

International journal of gynecology and obstetrics, 2003-07, Vol.82 (1), p.111-114

Freedman, L.P.

2003

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Using human rights in maternal mortality programs: from analysis to strategy

International journal of gynecology and obstetrics, 2001-10, Vol.75 (1), p.51-60

Freedman, L.P

2001

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Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

Nature (London), 1991-08, Vol.352 (6335), p.497-505

1991

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p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells

Genes & development, 2000-10, Vol.14 (20), p.2581-2586

2000

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Discrete Roles for Peroxisome Proliferator-Activated Receptor γ and Retinoid X Receptor in Recruiting Nuclear Receptor Coactivators

Molecular and Cellular Biology, 2000-11, Vol.20 (21), p.8008-8017

2000

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Increasing the Complexity of Coactivation in Nuclear Receptor Signaling

Cell, 1999-04, Vol.97 (1), p.5-8

Freedman, Leonard P

1999

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A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARα and T18 oncoproteins

Nature genetics, 1999-11, Vol.23 (3), p.287-295

1999

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Mediator complexes and transcription

Current Opinion in Cell Biology, 2001-06, Vol.13 (3), p.274-280

2001

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Health care financing and utilization of maternal health services in developing countries

Health policy and planning, 2007-09, Vol.22 (5), p.303-310

2007

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Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937

Genes & development, 1996-01, Vol.10 (2), p.142-153

1996

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Transcriptional repression of the interleukin-2 gene by vitamin D3: direct inhibition of NFATp/AP-1 complex formation by a nuclear hormone receptor

Molecular and Cellular Biology, 1995-10, Vol.15 (10), p.5789-5799

1995

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DNA target selectivity by the vitamin D3 receptor: mechanism of dimer binding to an asymmetric repeat element

Proceedings of the National Academy of Sciences - PNAS, 1993-07, Vol.90 (13), p.6310-6314

1993

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Solution Structure of the Glucocorticoid Receptor DNA-Binding Domain

Science (American Association for the Advancement of Science), 1990-07, Vol.249 (4965), p.157-160

1990

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Melanoma metastasis suppression by chromosome 6: Evidence for a pathway regulated by CRSP3 and TXNIP

Cancer research (Chicago, Ill.), 2003-01, Vol.63 (2), p.432-440

2003

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Mutations in the glucocorticoid receptor zinc finger region that distinguish interdigitated DNA binding and transcriptional enhancement activities

Genes & development, 1989-10, Vol.3 (10), p.1590-1601

1989

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Transcriptional activation of the human p21(WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation

The Journal of biological chemistry, 1996-12, Vol.271 (49), p.31723-31728

1996

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Transcriptional targets of the vitamin D3 receptor-mediating cell cycle arrest and differentiation

The Journal of nutrition, 1999-02, Vol.129 (2), p.581-586

FREEDMAN, L. P

1999

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Anatomy of the steroid receptor zinc finger region

Endocrine reviews, 1992-05, Vol.13 (2), p.129-145

FREEDMAN, L. P

1992

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DNA sequences that act as high affinity targets for the vitamin D3 receptor in the absence of the retinoid X receptor

Molecular endocrinology (Baltimore, Md.), 1994-03, Vol.8 (3), p.265-273

1994

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Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc

Oncogene, 2001-03, Vol.20 (14), p.1688-1702

2001

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The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain

Nature (London), 1988-08, Vol.334 (6182), p.543-546

1988

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Reciprocal Recruitment of DRIP/Mediator and p160 Coactivator Complexes in Vivo by Estrogen Receptor

The Journal of biological chemistry, 2002-04, Vol.277 (17), p.14359-14362

2002

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Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins

The EMBO journal, 1999-10, Vol.18 (19), p.5380-5388

1999

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The Impact of Preclinical Irreproducibility on Drug Development

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex

Human rights, constructive accountability and maternal mortality in the Dominican Republic: a commentary

Using human rights in maternal mortality programs: from analysis to strategy

Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells

Discrete Roles for Peroxisome Proliferator-Activated Receptor γ and Retinoid X Receptor in Recruiting Nuclear Receptor Coactivators

Increasing the Complexity of Coactivation in Nuclear Receptor Signaling

A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARα and T18 oncoproteins

Mediator complexes and transcription

Health care financing and utilization of maternal health services in developing countries

Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937

Transcriptional repression of the interleukin-2 gene by vitamin D3: direct inhibition of NFATp/AP-1 complex formation by a nuclear hormone receptor

DNA target selectivity by the vitamin D3 receptor: mechanism of dimer binding to an asymmetric repeat element

Solution Structure of the Glucocorticoid Receptor DNA-Binding Domain

Melanoma metastasis suppression by chromosome 6: Evidence for a pathway regulated by CRSP3 and TXNIP

Mutations in the glucocorticoid receptor zinc finger region that distinguish interdigitated DNA binding and transcriptional enhancement activities

Transcriptional activation of the human p21(WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation

Transcriptional targets of the vitamin D3 receptor-mediating cell cycle arrest and differentiation

Anatomy of the steroid receptor zinc finger region

DNA sequences that act as high affinity targets for the vitamin D3 receptor in the absence of the retinoid X receptor

Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc

The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain

Reciprocal Recruitment of DRIP/Mediator and p160 Coactivator Complexes in Vivo by Estrogen Receptor

Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins

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