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Conformational ensembles explain NMR spectra of frozen intrinsically disordered proteins

Protein science, 2023-05, Vol.32 (5), p.e4628-n/a

2023

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In-Cell Sensitivity-Enhanced NMR of Intact Viable Mammalian Cells

Journal of the American Chemical Society, 2021-11, Vol.143 (44), p.18454-18466

2021

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Sensitivity-Enhanced NMR Reveals Alterations in Protein Structure by Cellular Milieus

Cell, 2015-10, Vol.163 (3), p.620-628

2015

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The role of conformational entropy in molecular recognition by calmodulin

Nature chemical biology, 2010-05, Vol.6 (5), p.352-358

2010

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In-Cell NMR of Intact Mammalian Cells Preserved with the Cryoprotectants DMSO and Glycerol Have Similar DNP Performance

Frontiers in molecular biosciences, 2022-01, Vol.8, p.789478-789478

2022

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Orientation of aromatic residues in amyloid cores: Structural insights into prion fiber diversity

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (48), p.17158-17163

2014

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Stability of the nitroxide biradical AMUPol in intact and lysed mammalian cells

Journal of magnetic resonance (1997), 2022-03, Vol.336, p.107150-107150, Article 107150

2022

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DNP-assisted solid-state NMR enables detection of proteins at nanomolar concentrations in fully protonated cellular milieu

Journal of biomolecular NMR, 2024-06, Vol.78 (2), p.95-108

2024

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DNP-Assisted NMR Investigation of Proteins at Endogenous Levels in Cellular Milieu

Methods in enzymology, 2019-01, Vol.615, p.373

2019

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Combining DNP NMR with segmental and specific labeling to study a yeast prion protein strain that is not parallel in-register

Proceedings of the National Academy of Sciences - PNAS, 2017-04, Vol.114 (14), p.3642-3647

2017

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Amyloid fibrils embodying distinctive yeast prion phenotypes exhibit diverse morphologies

FEMS yeast research, 2018-09, Vol.18 (6), p.1

2018

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Cryogenic Sample Loading into a Magic Angle Spinning Nuclear Magnetic Resonance Spectrometer that Preserves Cellular Viability

Journal of visualized experiments, 2020-09 (163)

2020

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Aggregation and Fibril Structure of AβM01–42 and Aβ1–42

Biochemistry (Easton), 2017-09, Vol.56 (36), p.4850-4859

2017

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Michler’s hydrol blue elucidates structural differences in prion strains

Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (47), p.29677-29683

2020

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Sensitivity-Enhanced Dnp NMR for In Situ Structural Biology

Biophysical journal, 2019-02, Vol.116 (3), p.203a-203a

Frederick, Kendra K.

2019

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Distinct Prion Strains Are Defined by Amyloid Core Structure and Chaperone Binding Site Dynamics

Chemistry & biology, 2014-02, Vol.21 (2), p.295-305

2014

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Arylamide Derivatives as Peptidomimetic Inhibitors of Calmodulin

Organic letters, 2006-01, Vol.8 (2), p.223-225

2006

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Stability of the nitroxide bi-radical AMUPol in intact and lysed mammalian cells

Journal of magnetic resonance (1997), 2022-01, Vol.336, p.107150-107150

2022

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Control of Adenosylmethionine-Dependent Radical Generation in Biotin Synthase: A Kinetic and Thermodynamic Analysis of Substrate Binding to Active and Inactive Forms of BioB

Biochemistry (Easton), 2003-03, Vol.42 (9), p.2708-2719

2003

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Cryogenic Sample Loading into a Magic Angle Spinning Nuclear Magnetic Resonance Spectrometer that Preserves Cellular Viability

Journal of visualized experiments, 2020-09 (163)

2020

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Motion and Conformational Entropy in Protein Function: Creation of an NMR-Based Entropy Meter

Biophysical journal, 2015-01, Vol.108 (2), p.60a-60a

2015

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Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases

Cellular signalling, 2006, Vol.18 (1), p.69-82

2006

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Spinal Anesthesia or General Anesthesia for Hip Surgery in Older Adults

The New England journal of medicine, 2021-11, Vol.385 (22), p.2025-2035

2021

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Rates and causes of death after release from incarceration among 1 471 526 people in eight high-income and middle-income countries: an individual participant data meta-analysis

The Lancet (British edition), 2024-05, Vol.403 (10438), p.1779-1788

2024

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Conformational ensembles explain NMR spectra of frozen intrinsically disordered proteins

In-Cell Sensitivity-Enhanced NMR of Intact Viable Mammalian Cells

Sensitivity-Enhanced NMR Reveals Alterations in Protein Structure by Cellular Milieus

The role of conformational entropy in molecular recognition by calmodulin

In-Cell NMR of Intact Mammalian Cells Preserved with the Cryoprotectants DMSO and Glycerol Have Similar DNP Performance

Orientation of aromatic residues in amyloid cores: Structural insights into prion fiber diversity

Stability of the nitroxide biradical AMUPol in intact and lysed mammalian cells

DNP-assisted solid-state NMR enables detection of proteins at nanomolar concentrations in fully protonated cellular milieu

DNP-Assisted NMR Investigation of Proteins at Endogenous Levels in Cellular Milieu

Combining DNP NMR with segmental and specific labeling to study a yeast prion protein strain that is not parallel in-register

Amyloid fibrils embodying distinctive yeast prion phenotypes exhibit diverse morphologies

Cryogenic Sample Loading into a Magic Angle Spinning Nuclear Magnetic Resonance Spectrometer that Preserves Cellular Viability

Aggregation and Fibril Structure of AβM01–42 and Aβ1–42

Michler’s hydrol blue elucidates structural differences in prion strains

Sensitivity-Enhanced Dnp NMR for In Situ Structural Biology

Distinct Prion Strains Are Defined by Amyloid Core Structure and Chaperone Binding Site Dynamics

Arylamide Derivatives as Peptidomimetic Inhibitors of Calmodulin

Stability of the nitroxide bi-radical AMUPol in intact and lysed mammalian cells

Control of Adenosylmethionine-Dependent Radical Generation in Biotin Synthase: A Kinetic and Thermodynamic Analysis of Substrate Binding to Active and Inactive Forms of BioB

Cryogenic Sample Loading into a Magic Angle Spinning Nuclear Magnetic Resonance Spectrometer that Preserves Cellular Viability

Motion and Conformational Entropy in Protein Function: Creation of an NMR-Based Entropy Meter

Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases

Serial assessment of measurable residual disease in medulloblastoma liquid biopsies

Spinal Anesthesia or General Anesthesia for Hip Surgery in Older Adults

Rates and causes of death after release from incarceration among 1 471 526 people in eight high-income and middle-income countries: an individual participant data meta-analysis

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